Navigation Links
Genes May Trigger Repeated Premature Birth In Blacks

Black women may be genetically predisposed to giving birth prematurely, according to a new study from Washington University//.

The research is an important first step toward identifying women at risk for delivering babies too early and eventually could lead to treatments.

Researchers at the university examined 711,015 records of births between 1989 and 1997 kept by the Missouri Department of Health and Senior Services. The data showed that African-American women were nearly three times more likely than white women to have a baby prematurely.

Scientists have known there is a racial disparity, but they debate its cause. The Washington University researchers, led by Dr. Louis J. Muglia, wanted to find out whether genetics played a role. Previous studies have hinted that genetic factors might be important, but none has shown proof, Muglia said. He directs the new Center for Preterm Birth Research at Washington University.

His group decided to look at women for whom genetics was most likely to play a role — women who had more than one baby prematurely. Having one baby prematurely is the greatest risk factor for having another preterm birth. That's true for all women.

But the study showed that black women are at even higher risk of having more than one preterm baby. The rate of recurring preterm births for African-American women was 21.5 percent, in whites 9.2 percent. Even after adjusting for variables such as social and economic status, education levels, smoking and maternal medical problems, including diabetes and high blood pressure, black women were still four times more likely to have recurrent preterm births.

The black women also delivered two weeks earlier than white women with multiple preterm babies. The black mothers gave birth, on average, at 31 weeks gestation, while white moms averaged 33 weeks gestation.

Preterm birth is usually defined as delivery at less than 37 weeks of gestation. Th e new study used 34 weeks gestation as a cut-off to avoid any errors in calculating the due date. The researchers considered 37 weeks gestation to 42 weeks full-term.

The study appears today in the American Journal of Obstetrics and Gynecology. The March of Dimes funded the study.

The data also revealed that a woman who had multiple preterm births tended to deliver at about the same stage in each pregnancy. Almost half of the mothers in the study had their babies within two weeks of the gestation time of their first premature child. It is unlikely that infections or other environmental factors would trigger premature births during such a narrow window, said Dr. Michael P. Nageotte, the immediate past president of the Society for Maternal-Fetal Medicine.

That clustering raises the possibility that a genetic clock controls the timing of birth and gets turned on too early in some women, Nageotte said.

The researchers concluded that genetics are the underlying reason for premature births.

Source-Bio-Bio Technology
SRI
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/17/2017)... ... August 17, 2017 , ... Georgia Urology, ... Dr. Kristi Hebert to its newest location in East Cobb (4800 ... Dr. Hebert come aboard,” said Dr. Mark A. Haber, Georgia Urology’s managing partner. “She ...
(Date:8/17/2017)... Houston, Texas (PRWEB) , ... August 17, 2017 ... ... Dr. Rukmini “Vinaya” Rednam distinguishes herself once more by being among Houston’s first ... clientele receives the highest quality plastic surgery care without disrupting busy schedules and ...
(Date:8/17/2017)... ... ... SeQuel Response announced today that for the fourth consecutive year, ... companies in the U.S., putting it in the top 10 percent of applicants nationwide. ... Inc. 5000 over the years, only a fraction have made the list more ...
(Date:8/17/2017)... ... 2017 , ... CareAcademy, a provider of specialized online training ... in seed funding to further expand its course portfolio and increase its market ... the company’s primary investors. , Founded in 2016, CareAcademy currently serves ...
(Date:8/17/2017)... Ca (PRWEB) , ... August 17, 2017 , ... Centrifugation ... useful tools in the laboratory that we can no longer do without. And just ... the lifetime of your device. , In this webinar, attendees will learn about the ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 ... from continuing operations Second-quarter ... $110 million Second-quarter 2017 ... Second-quarter 2017 adjusted diluted ... percent to $0.93 Second-quarter ...
(Date:8/7/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO ) today ... effective Aug. 7, 2017. ... interests and will serve as president emeritus during a planned, ... in multiple leadership roles since he joined Diplomat with the ... provided decisive, strategic leadership which continues to benefit our patients ...
(Date:8/4/2017)... , Aug. 4, 2017 The search ... shortly after a physician/patient consult has long been the ... was a notable focus of the largest meeting of ... according to healthcare market research firm Kalorama Information.  The ... testing (POCT) offerings or related supplies and software were ...
Breaking Medicine Technology: