Navigation Links
Genes May Trigger Repeated Premature Birth In Blacks

Black women may be genetically predisposed to giving birth prematurely, according to a new study from Washington University//.

The research is an important first step toward identifying women at risk for delivering babies too early and eventually could lead to treatments.

Researchers at the university examined 711,015 records of births between 1989 and 1997 kept by the Missouri Department of Health and Senior Services. The data showed that African-American women were nearly three times more likely than white women to have a baby prematurely.

Scientists have known there is a racial disparity, but they debate its cause. The Washington University researchers, led by Dr. Louis J. Muglia, wanted to find out whether genetics played a role. Previous studies have hinted that genetic factors might be important, but none has shown proof, Muglia said. He directs the new Center for Preterm Birth Research at Washington University.

His group decided to look at women for whom genetics was most likely to play a role — women who had more than one baby prematurely. Having one baby prematurely is the greatest risk factor for having another preterm birth. That's true for all women.

But the study showed that black women are at even higher risk of having more than one preterm baby. The rate of recurring preterm births for African-American women was 21.5 percent, in whites 9.2 percent. Even after adjusting for variables such as social and economic status, education levels, smoking and maternal medical problems, including diabetes and high blood pressure, black women were still four times more likely to have recurrent preterm births.

The black women also delivered two weeks earlier than white women with multiple preterm babies. The black mothers gave birth, on average, at 31 weeks gestation, while white moms averaged 33 weeks gestation.

Preterm birth is usually defined as delivery at less than 37 weeks of gestation. Th e new study used 34 weeks gestation as a cut-off to avoid any errors in calculating the due date. The researchers considered 37 weeks gestation to 42 weeks full-term.

The study appears today in the American Journal of Obstetrics and Gynecology. The March of Dimes funded the study.

The data also revealed that a woman who had multiple preterm births tended to deliver at about the same stage in each pregnancy. Almost half of the mothers in the study had their babies within two weeks of the gestation time of their first premature child. It is unlikely that infections or other environmental factors would trigger premature births during such a narrow window, said Dr. Michael P. Nageotte, the immediate past president of the Society for Maternal-Fetal Medicine.

That clustering raises the possibility that a genetic clock controls the timing of birth and gets turned on too early in some women, Nageotte said.

The researchers concluded that genetics are the underlying reason for premature births.

Source-Bio-Bio Technology

Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:

(Date:11/29/2015)... , ... November 29, 2015 , ... Khanna Vision Institute ... Board of Ophthalmology on November 25th 2015. Peer Certification by the Board is ... his specialty. Certification in Ophthalmology is first obtained after the completion of three years ...
(Date:11/29/2015)... IL (PRWEB) , ... November 29, 2015 , ... Effective ... In addition starting on Black Friday Target is offering a “Buy One ... This is a rare opportunity to purchase IguanaMed at a discounted price. ...
(Date:11/28/2015)... ... November 28, 2015 , ... Trying to relax on ... the COUCH BUDDY. "I conceived of this design due to personal experience with a ... users. It promotes relaxation and convenience, as well as increases support. It also makes ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the conversation at the recent 2015 American Dental Association meeting in Washington D.C. revolved ... can help protect a patient’s overall health. The talk stressed the link between periodontal ...
(Date:11/27/2015)... , ... November 27, 2015 , ... A team of ... ways to treat it. Surviving Mesothelioma has just posted the findings on the website. ... Hospital Zurich analyzed the cases of 136 mesothelioma patients who were treated with chemotherapy ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Cell Surface Testing Market: Supplier Shares, ... their offering.  --> ... the  "2016 Future Horizons and Growth ...
(Date:11/26/2015)... , Nov. 26, 2015 Research and ... the "Advanced Wound Care Market by Type (Dressings, ... End User (In-Patient Facility, Out-Patient Facility), and Geography - ... --> --> ... description, definition and forecast of the global advanced wound ...
(Date:11/26/2015)... ) has announced ... High Viscosity Drugs" report to their offering. ... addition of the "Self Administration of High ... --> Research and Markets ( ) ... Administration of High Viscosity Drugs" report to ...
Breaking Medicine Technology: