Navigation Links
Genes And Environmental Factors Determine Stress Response

Researchers from Duke university Medical Center have established that an individual’s health and well being is largely influenced by a complex interplay between genetic and environmental factors//. In addition, genes might play a crucial role in determining the psychological and biological response to a stressful environment.

The results of four such studies that examined the genetic-environment association were presented at the annual meeting of the American Psychosomatic Society. The National Institute on Aging and the National Heart Lung and Blood Institute funded the studies.

The researchers examined the effect of mutation of a gene that produces monoamine oxidase-A. The enzyme is responsible for breakdown of serotonin and other neurotransmitters. Mutation of this gene can lead to either enhanced or decreased production of the chemical.

Neurotransmitters, as the name suggests are substances that communicate information to the brain. Therefore any change in level of these chemical substances can have a profound impact on brain function and other physiological functions, mediated by the brain such as glucose metabolism.

The mutation of the MAOA-uVNTR gene was found to determine the serotonin levels that had an indirect effect on blood levels of insulin, glucose and body mass index. This means that people who have a specific version of the gene could have an increased risk for development of diabetes and obesity.

Another study that examined the MAOA gene mutation in two different group of individuals; primary caregivers for spouses or relatives with Alzheimer’s disease and those who were similar to caregivers, but had no responsibility of care giving. It was found that the levels of stress hormones, more specifically in men were to a large extent dependent on the type of MAOA gene mutation. Men with less active MAOA gene were at increased risk of developing health problems owing to their inability to cope up with the stress related to care giving.

The result of a study that evaluated the effect of a family of genes, known to influence stress response and high blood pressure (hypertension) was also presented at the symposium. The researchers hypothesize that genes which remain dormant when life is still and calm can become active under stress.

The importance of using genetic markers to identify at risk individuals for development of stress (those under acute/chronic stress, in addition to environmental factors such as high-calorie diet) was further highlighted. This could eventually pave way for effective treatment strategies or can assist in closely monitoring onset of diabetes or obesity.


Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Genes for Vision discovered
5. Genes Found To Help Leukemia Treatment
6. Cardiac Valve Disease Linked To Genes
7. Genes Linked To Cigarette Addiction
8. Genes from saliva may predict oral and breast cancer
9. Genes More Important Than Exercise for Bad Cholesterol
10. Genes responsible for social behavior of us
11. Genes to Extend Longevity Discovered
Post Your Comments:

(Date:11/28/2015)... ... November 28, 2015 , ... Safe storage for contraceptive ... two inventors, one from Lakewood, New Jersey and the other from Bradley Beach, New ... PROTECTOR to save the expense of having to replace NuvaRings more often than necessary. ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published November ... meeting in Washington D.C. revolved around the fact that proper dental care, both at-home ... stressed the link between periodontal disease (more commonly referred to as gum disease) and ...
(Date:11/27/2015)... ... November 27, 2015 , ... An inventor, from Hopkinsville, Ky., ... medications at home, so he invented the patent-pending ELECTRONIC M.D. , The ELECTRONIC ... In doing so, it could help to prevent potential overdose situations. As a ...
(Date:11/27/2015)... ... , ... MPWH, the No.1 Herpes-only dating community in the world, revealed that over 50% of ... than 3.7 billion people under the age of 50 – or 67% of the population ... global estimates of HSV-1 infection . , "The data shocks us highly!" said Michelle ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in ... for mental health and wellness consultation, has collaborated with a leading web-based marketplace ... knowledge gap experienced by parents and bring advice from parenting experts within their ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 --> ... SyMRI to find optimal contrast weighting of MRI for ... has signed a research agreement with SyntheticMR in order to ... SyMRI, it is possible to generate multiple contrast images from ... patient has left, thus making it possible to both fine ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Testing Market: Supplier Shares, Competitive ... offering.  --> ) ... "2016 Future Horizons and Growth Strategies ...
(Date:11/26/2015)... PUNE, India , November 26, ... --> --> ... Research Report" and "Investigation Report on ... 2019 and 2021 forecasts data and ... library. . ...
Breaking Medicine Technology: