Navigation Links
Gene variation simulates cholesterol response to oestrogen

According to a new study shows that women with a specific gene variant have a dramatic increase in 'good' cholesterol when they take oestrogen.// Previous research suggests that hormone replacement therapy (HRT) might protect women from heart disease. Now doctors at Forest University have discovered a strong genetic influence in how a woman's cholesterol profile responds to HRT.

An analysis of over 300 women with heart problems who took HRT or placebo showed that those with a specific gene variant had dramatic increases in high density lipoprotein (HDL or 'good' cholesterol). The gene concerned is called the oestrogen receptor alpha and, in this study, 20 per cent of the women carried it. They had a two to three times greater increase in HDL compared to women who did not have this variant of the gene.

Having high HDL should decrease the risk of heart disease although it is not yet known whether the current findings will mean fewer heart attacks for these women. The study may explain why previous research has shown no particular benefit from HRT in women with established heart disease - such research focusses on all women, not just the subgroup with the gene variant. The dramatic increases in HRT in this group would be diluted by results from those women who don't respond so well.

More research is needed before genetic testing for oestrogen receptor alpha can be recommended for women considering HRT. But this study promises a way of detecting those women who can most benefit from hormone replacement.


'"/>




Page: 1

Related medicine news :

1. Lifestyle variation can cut diabetes hazard
2. Differing reactions to anti clotting drugs may be due to genetic variation.
3. A better way to measure cholesterol
4. Genetics and cholesterol levels
5. Frequent meals can reduce cholesterol
6. Lecithin lowers cholesterol absorption in body
7. Step Aerobics Increases good cholesterol
8. Women are at risk with raised cholesterol
9. Functional foods reduce cholesterol
10. Exercise has a undeniable effect on cholesterol
11. Discovering cholesterol-absorbing genes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... ... April 25, 2017 , ... Splashtop ... Mirroring360 Pro . This new addition to the Mirroring360 product family combines device ... business. , Mirroring360 Pro enables educators, business professionals and individuals to stream or ...
(Date:4/25/2017)... ... April 25, 2017 , ... As President ... are preparing for how his administration could impact the employee benefits industry. James ... changes are most likely to make it through Congress. His discussion will focus ...
(Date:4/25/2017)... ... April 25, 2017 , ... Patients who would like to ... a fraction of the time as traditional braces – Wilckodontics®. Dr. Victoria Chen, ... offers this revolutionary treatment with or without a referral. , Wilckodontics is ...
(Date:4/25/2017)... ... 2017 , ... Buyers and sellers in the thriving multi-billion dollar cannabis marketplace ... help but be heartened by the industry’s current surge. But another thing that unifies ... smell.” At last they can simply, safely and effectively end their aroma anguish ...
(Date:4/25/2017)... Fl (PRWEB) , ... April 25, 2017 , ... There ... Memorial Regional Hospital, according to a special report in the May issue of Consumer ... its highest quality ranking for results achieved during and after coronary bypass and ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... Tenn. and DALLAS , April 19, 2017 ... announced that the first patients in Nashville ... device in the Lower Esophageal Sphincter Stimulation for GERD ... implantable device designed to provide long-term reflux control by ... GERD affects nearly 65 million people in ...
(Date:4/19/2017)... SAN DIEGO , April 19, 2017 /PRNewswire/ ... ("Sorrento"), an antibody-centric, clinical-stage biopharmaceutical company developing new ... today announced the closing of its previously announced ... common stock at a public offering price of ... commissions and estimated offering expenses payable by Sorrento.  ...
(Date:4/19/2017)... 2017  New research provides evidence that an old drug ... a study released today that will be presented at the ... Boston , April 22 to 28, 2017. ... Parkinson,s disease, the oral drug levodopa has long been considered ... as the disease progresses, the effects of the medication can ...
Breaking Medicine Technology: