Navigation Links
Gene variant foretells diabetic neuropathy

A gene variant that is linked to an increase in the risk of Alzheimer's disease also predicts which people with diabetes are most likely to suffer neuropathy. In diabetes, impaired circulation may cause neuropathy in the lower limbs - that is, //peripheral nerve damage leading to pain and numbness. In severe cases, amputation may even be necessary. Researchers at Duke University in the US have now identified a gene variant which makes people more likely to suffer from peripheral neuropathy if they have diabetes.

The gene variant is APOE4, which has also been implicated in increased risk for Alzheimer's disease. In the current study, 187 people with diabetes were found to have more severe peripheral neuropathy, if they had the APOE4 variant, compared to those with other variants of APOE. It was as if these patients had had diabetes for 15 years longer, say the researchers. It's not clear how APOE4 is linked with peripheral neuropathy, however. It may be that it somehow blocks the circulation in the lower limb or impairs the secretion of the growth factors which the peripheral nerves need to be healthy.


Page: 1

Related medicine news :

1. Sugar variant may make a world of difference to Alzheimers disease
2. Gene variants hold clues about vulnerability to cardiovascular disease
3. Gastrointestinal ills more common in diabetics
4. Pollution- hazardous for diabetics
5. New treatment for diabetics
6. Breast screening among diabetic women
7. Needle free future for diabetics
8. Care for footwear not required diabetic patients
9. Nightlights could ward diabetic blindness
10. Protein in diabetic neuropathy treatment
11. New target for antidiabetic agents identified
Post Your Comments:

(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be ...
(Date:6/24/2016)... ... ... makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum ... by 2020 and then adjusting it yearly to increase at the same rate as the ... wage floor does not erode again, and make future increases more predictable. , The company ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The ... published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative ... has initiated cultivation and processing operations at its production facility, and opened its ... Puradigm is the manufacturer of a complete system of proactive air and surface ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners ... extensive sequencing and genomics experience, as Vice President of North American Capital Sales at ... responsible for leading the sales team in the commercialization of the HTG EdgeSeq system ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 ... today announced the appointment of Dr. Edward ... as a Non-Executive Director, effective June 23, 2016.Dr. ... Compensation and Nominations and Governance Committees.  As a ... will provide independent expertise and strategic counsel to ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
Breaking Medicine Technology: