Navigation Links
Gene variant foretells diabetic neuropathy

A gene variant that is linked to an increase in the risk of Alzheimer's disease also predicts which people with diabetes are most likely to suffer neuropathy. In diabetes, impaired circulation may cause neuropathy in the lower limbs - that is, //peripheral nerve damage leading to pain and numbness. In severe cases, amputation may even be necessary. Researchers at Duke University in the US have now identified a gene variant which makes people more likely to suffer from peripheral neuropathy if they have diabetes.

The gene variant is APOE4, which has also been implicated in increased risk for Alzheimer's disease. In the current study, 187 people with diabetes were found to have more severe peripheral neuropathy, if they had the APOE4 variant, compared to those with other variants of APOE. It was as if these patients had had diabetes for 15 years longer, say the researchers. It's not clear how APOE4 is linked with peripheral neuropathy, however. It may be that it somehow blocks the circulation in the lower limb or impairs the secretion of the growth factors which the peripheral nerves need to be healthy.


'"/>




Page: 1

Related medicine news :

1. Sugar variant may make a world of difference to Alzheimers disease
2. Gene variants hold clues about vulnerability to cardiovascular disease
3. Gastrointestinal ills more common in diabetics
4. Pollution- hazardous for diabetics
5. New treatment for diabetics
6. Breast screening among diabetic women
7. Needle free future for diabetics
8. Care for footwear not required diabetic patients
9. Nightlights could ward diabetic blindness
10. Protein in diabetic neuropathy treatment
11. New target for antidiabetic agents identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... Viejo, California (PRWEB) , ... June 26, 2016 , ... ... Final Cut Pro X. , "Film editors can give their videos a whole new ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women ... diagnosed with endometriosis. These women need a treatment plan to not only alleviate ... that can help for preservation of fertility and ultimately achieving a pregnancy. The ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... RIDGE, Ill. and INDIANAPOLIS ... of students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship ... The 2016 scholarship winners, announced today online at ... to let type 1 diabetes stand in the way ... Diabetes has supported the Foundation,s scholarship program since 2012, ...
(Date:6/23/2016)... 2016 The vast majority of dialysis patients ... Treatments are usually 3 times a week, with treatment ... travel time, equipment preparation and wait time.  This regimen ... for patients who are elderly and frail.  Many elderly ... rehabilitation centers for some duration of time. ...
Breaking Medicine Technology: