Navigation Links
Gene therapy restores sight

US scientists report they have successfully used gene therapy to restore sight to animals with a rare inherited form of blindness. A team of scientists led by Jean Bennett, at the University of Pennsylvania, reported their success in this month's Nature Genetics.Their experiment involved dogs with Leber congenital amaurosis (LCA), a form of blindness, that also affects human infants and for which there is no treatment.

The disease involves a defect in the genes responsible for the retina's ability to translate light into nerve impulses.// In humans, LCA causes severe rapid onset of blindness, a process which begins before birth so infants are born partially blind.

Bennett's team injected the eyeballs of dogs born with LCA with cells modified to contain the appropriate functional genes which restored the animals' sight.Humans are next"This is a dog model of a human disease," said Dr Jonathon Stone of Sydney University who studies the environmental factors contributing to blindness. "It's impressive that the researchers have shown such a degree of improvement in sight - a several fold increase."

However, Dr Stone told ABC Science Online that applying this work to humans would not be immediate nor straightforward."In the dog, LCA shows a slow progression and so the researchers were able to work with adult dogs," he said. "In humans, any gene therapy would have to occur before birth".

Dr Stone said a further challenge would be identifying the exact genetic defect for LCA. "Different people with LCA have defects in different genes, or different parts of the same gene, and this varies from one continent to another," he said. He was confident, nevertheless, that geneticists could achieve this.


'"/>




Page: 1

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Antioxidants protect health tissue in people undergoing radiation therapy.
3. Distraction therapy found very effective in postoperative patients
4. Acupuncture superseeds massage therapy for short term relief of pain
5. Ovarian cancer in relationship with Hormone therapy
6. New therapy better at increasing bone density
7. Gene therapy - Aim to improve blood flow
8. Heat therapy relieves back pain
9. Radiotherapy helps in colon cancer
10. New therapy for pimples
11. Support therapy helps breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/15/2018)... ... September 14, 2018 , ... ... campaign will showcase the innovative work being done within rare diseases research, diagnostics, ... for those living with rare diseases. , Clay Matthews, Super ...
(Date:9/13/2018)... Mont. (PRWEB) , ... September 13, 2018 , ... Pulsara ... Annual Health IT + Revenue Cycle Conference on September 19-22 in Chicago. Dr. ... separate panels as well as a talk titled, “Your Clinical Communication & Collaboration (CC&C) ...
(Date:9/12/2018)... (PRWEB) , ... September 13, 2018 , ... Donaldson Plastic ... companies, as well as Columbus Business First's Fast 50 list of central Ohio's fastest ... with a 3-year growth rate of 81 percent. It is the only medical practice ...
(Date:9/7/2018)... ... September 07, 2018 , ... ... , the only OSHA authorized OTI Education Center headquartered in Northern California, is ... who feel they have experienced retaliation in response to engaging in activity protected ...
(Date:9/2/2018)... ... September 02, 2018 , ... Eaton Hotel in Washington, DC ... itself, which opened this week, inspires creativity and innovation among its guests, whether ... Hotel DC currently features 209 hotel rooms, a wellness center, a radio station, ...
Breaking Medicine News(10 mins):
(Date:9/15/2018)... ... September 14, 2018 , ... ... sequencing to enable greater library coverage. However, severe gaps and limitations associated ... remain. , Multiplexed phage display provides a simple, robust, and seamless high-throughput-ready ...
(Date:9/13/2018)... ... , ... Dr. Rod J. Rohrich is pleased to announce that registration is ... experts from around the world, will take place from March 22nd and 23rd, 2019. ... anatomy to complex surgical procedures and detailed analysis of revision rhinoplasty . Formats ...
(Date:9/12/2018)... ... September 12, 2018 , ... ... of Express Surveys as part of its Population Engage patient experience suite. ... feedback from patients, giving the provider organization a wealth of strategic and tactical ...
Breaking Medicine Technology: