Navigation Links
Gene therapy restores sight

US scientists report they have successfully used gene therapy to restore sight to animals with a rare inherited form of blindness. A team of scientists led by Jean Bennett, at the University of Pennsylvania, reported their success in this month's Nature Genetics.Their experiment involved dogs with Leber congenital amaurosis (LCA), a form of blindness, that also affects human infants and for which there is no treatment.

The disease involves a defect in the genes responsible for the retina's ability to translate light into nerve impulses.// In humans, LCA causes severe rapid onset of blindness, a process which begins before birth so infants are born partially blind.

Bennett's team injected the eyeballs of dogs born with LCA with cells modified to contain the appropriate functional genes which restored the animals' sight.Humans are next"This is a dog model of a human disease," said Dr Jonathon Stone of Sydney University who studies the environmental factors contributing to blindness. "It's impressive that the researchers have shown such a degree of improvement in sight - a several fold increase."

However, Dr Stone told ABC Science Online that applying this work to humans would not be immediate nor straightforward."In the dog, LCA shows a slow progression and so the researchers were able to work with adult dogs," he said. "In humans, any gene therapy would have to occur before birth".

Dr Stone said a further challenge would be identifying the exact genetic defect for LCA. "Different people with LCA have defects in different genes, or different parts of the same gene, and this varies from one continent to another," he said. He was confident, nevertheless, that geneticists could achieve this.


'"/>




Page: 1

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Antioxidants protect health tissue in people undergoing radiation therapy.
3. Distraction therapy found very effective in postoperative patients
4. Acupuncture superseeds massage therapy for short term relief of pain
5. Ovarian cancer in relationship with Hormone therapy
6. New therapy better at increasing bone density
7. Gene therapy - Aim to improve blood flow
8. Heat therapy relieves back pain
9. Radiotherapy helps in colon cancer
10. New therapy for pimples
11. Support therapy helps breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco dentists, ... cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated to ... breathing. Oral appliances can offer significant relief to about 75 percent of people ...
(Date:10/12/2017)... ... 12, 2017 , ... Asante, a nationally recognized health system ... their existing home health joint venture through an agreement, effective October 1, 2017, ... venture home health company with Asante, delivering clinically integrated care, for the past ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the ... – Miles by Moonlight to raise money for the American Heart Association Heart Walk. ... , Teams will work together to keep their treadmills moving for 5 hours. Treadmills ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 25, 2017  EpiVax, Inc., a leader in ... immune-engineering today announced the launch of EpiVax Oncology ... personalized therapeutic cancer vaccines. EpiVax has provided $500,000 ... to enabling technologies to the new precision immunotherapy ... EpiVax Oncology as Chief Executive Officer. Gad brings ...
(Date:9/22/2017)... 2017  As the latest Obamacare repeal effort moves ... (R-LA) and Lindsey Graham (R-SC) medical ... device industry is in an odd place.  The industry ... excise tax on medical device sales passed along with ... patients, increased visits and hospital customers with the funding ...
(Date:9/19/2017)... ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device ... precise destruction of targeted tissues, announced three leadership team developments today:   ... Stopek, PhD ... ... Veteran medical device executive ...
Breaking Medicine Technology: