Navigation Links
Gene therapy restores sight

US scientists report they have successfully used gene therapy to restore sight to animals with a rare inherited form of blindness. A team of scientists led by Jean Bennett, at the University of Pennsylvania, reported their success in this month's Nature Genetics.Their experiment involved dogs with Leber congenital amaurosis (LCA), a form of blindness, that also affects human infants and for which there is no treatment.

The disease involves a defect in the genes responsible for the retina's ability to translate light into nerve impulses.// In humans, LCA causes severe rapid onset of blindness, a process which begins before birth so infants are born partially blind.

Bennett's team injected the eyeballs of dogs born with LCA with cells modified to contain the appropriate functional genes which restored the animals' sight.Humans are next"This is a dog model of a human disease," said Dr Jonathon Stone of Sydney University who studies the environmental factors contributing to blindness. "It's impressive that the researchers have shown such a degree of improvement in sight - a several fold increase."

However, Dr Stone told ABC Science Online that applying this work to humans would not be immediate nor straightforward."In the dog, LCA shows a slow progression and so the researchers were able to work with adult dogs," he said. "In humans, any gene therapy would have to occur before birth".

Dr Stone said a further challenge would be identifying the exact genetic defect for LCA. "Different people with LCA have defects in different genes, or different parts of the same gene, and this varies from one continent to another," he said. He was confident, nevertheless, that geneticists could achieve this.


'"/>




Page: 1

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Antioxidants protect health tissue in people undergoing radiation therapy.
3. Distraction therapy found very effective in postoperative patients
4. Acupuncture superseeds massage therapy for short term relief of pain
5. Ovarian cancer in relationship with Hormone therapy
6. New therapy better at increasing bone density
7. Gene therapy - Aim to improve blood flow
8. Heat therapy relieves back pain
9. Radiotherapy helps in colon cancer
10. New therapy for pimples
11. Support therapy helps breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2016)... (PRWEB) , ... May 23, 2016 , ... ... care retirement community, dedicated its new $11.5 million, 64-room assisted living center. After ... ceremony and ribbon cutting. , The new building provides the latest in ...
(Date:5/23/2016)... ... , ... According to an article published May 12th on the Medical Daily, as ... hygiene. The article points out that, as long as patients are brushing as they should ... frayed. Of course, these worn-out bristles won’t clean teeth and gum tissue as effectively, so ...
(Date:5/23/2016)... CA (PRWEB) , ... May 23, 2016 , ... Researchers ... is so routine. A fresh look at this technique may yield big benefits. ... reproducibility of experiments in a cell culture laboratory—and lessen the risk of ...
(Date:5/23/2016)... ... ... NYDNRehab, a New York City-based physical therapy clinic , is introducing ... type of technology, which was developed by world-renowned researcher Dr. Christopher Powers of University ... With over 10 million sport injuries per year in the United States, ...
(Date:5/23/2016)... ... May 23, 2016 , ... ComplianceOnline, the leading governance, risk and compliance advisory ... on September 15 and 16, 2016 in San Diego, CA. The two day ... will be one of the largest gatherings of medical device companies, suppliers, professionals and ...
Breaking Medicine News(10 mins):
(Date:5/19/2016)... AVIV, Israel , May 19, 2016 ... or the "Company"), an emerging global ophthalmic company focused ... product candidates which address ophthalmic conditions, announced today that ... Italy ) for the manufacturing, distribution, ... product for the treatment of dry eye syndrome (DES) ...
(Date:5/19/2016)... May 19, 2016 A new ... Heart Failure (CHF) Treatment Devices Market - Opportunities and ... devices market would reach $14.8 billion by 2022, at ... cardioverter-defibrillator (ICDs) segment is expected to dominate the world ... North America is projected to continue ...
(Date:5/19/2016)... 2016 A new report ... Robotics and Computer-Assisted Surgery Market - Opportunities and ... robotics and computer-assisted surgery market would reach $20.5 ... the highest revenue-generating segment, accounting for nearly half ... expected to maintain its dominance throughout the forecast ...
Breaking Medicine Technology: