Navigation Links
Gene therapy restores sight

US scientists report they have successfully used gene therapy to restore sight to animals with a rare inherited form of blindness. A team of scientists led by Jean Bennett, at the University of Pennsylvania, reported their success in this month's Nature Genetics.Their experiment involved dogs with Leber congenital amaurosis (LCA), a form of blindness, that also affects human infants and for which there is no treatment.//

The disease involves a defect in the genes responsible for the retina's ability to translate light into nerve impulses. In humans, LCA causes severe rapid onset of blindness, a process which begins before birth so infants are born partially blind.

Bennett's team injected the eyeballs of dogs born with LCA with cells modified to contain the appropriate functional genes which restored the animals' sight.Humans are next"This is a dog model of a human disease," said Dr Jonathon Stone of Sydney University who studies the environmental factors contributing to blindness. "It's impressive that the researchers have shown such a degree of improvement in sight - a several fold increase."

However, Dr Stone told ABC Science Online that applying this work to humans would not be immediate nor straightforward."In the dog, LCA shows a slow progression and so the researchers were able to work with adult dogs," he said. "In humans, any gene therapy would have to occur before birth".

Dr Stone said a further challenge would be identifying the exact genetic defect for LCA. "Different people with LCA have defects in different genes, or different parts of the same gene, and this varies from one continent to another," he said. He was confident, nevertheless, that geneticists could achieve this.


'"/>




Page: 1

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Antioxidants protect health tissue in people undergoing radiation therapy.
3. Distraction therapy found very effective in postoperative patients
4. Acupuncture superseeds massage therapy for short term relief of pain
5. Ovarian cancer in relationship with Hormone therapy
6. New therapy better at increasing bone density
7. Gene therapy - Aim to improve blood flow
8. Gene therapy restores sight
9. Heat therapy relieves back pain
10. Radiotherapy helps in colon cancer
11. New therapy for pimples
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... ... April 28, 2017 , ... ... (UCAOA) and College of Urgent Care Medicine will host industry leaders for the ... speakers will help those in the industry adapt to the issues currently affecting ...
(Date:4/28/2017)... ... April 28, 2017 , ... Researchers at ... of ActiGraph’s CentrePoint Data Hub in a sample of participants enrolled ... wearable activity and sleep monitoring solutions for the global scientific community. The company’s ...
(Date:4/28/2017)... , ... April 28, 2017 , ... Rob Lowe is ... now he has leant his presence to an educational purpose as the host of ... important one being cancer. In a recent episode, the series focuses on thyroid cancer. ...
(Date:4/27/2017)... ... April 27, 2017 , ... Healthcare companies are trying to meet talent shortages ... outdated healthcare executive resume. , “If you’re a healthcare executive open to new opportunities ... if it’s as ready as you are for a new job search. I’ve heard ...
(Date:4/27/2017)... ... April 27, 2017 , ... Goodcents Deli Fresh Subs announced ... Lincoln, Neb. area this year. , The first new location will open at ... will open at 84th and Northern Lights Drive this fall. And the third location ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... LUND, Sweden , April 20, 2017 /PRNewswire/ ... OTCQX: NEVPF) ("NeuroVive") today announced positive preclinical ... company,s preclinical compound for non-alcoholic steatohepatitis (NASH), ... NV556 has previously ... STAM™ NASH model. Today, NeuroVive,s scientists present ...
(Date:4/19/2017)... Calif. , April 19, 2017  IRIDEX Corporation ... will release financial results for the first quarter 2017 ... 2017.  The Company,s management team will host a corresponding ... p.m. ET. Investors interested in listening to ... 707-0665 for domestic callers or (703) 326-3030 for international ...
(Date:4/19/2017)...  Sorrento Therapeutics, Inc. (NASDAQ: SRNE ... new treatments for cancer and other unmet medical ... announced underwritten public offering of 23,625,084 shares of ... of $2.00 per share, before deducting underwriting discounts ... Sorrento.  The net proceeds to Sorrento from this ...
Breaking Medicine Technology: