Navigation Links
Gene mutation identified for inherited pain syndrome

Researchers have identified the single mutation of the gene involved in causing// the condition of inherited pain syndrome or primary erythromelalgia.

Investigators from Yale School of Medicine have reported in their research findings that the single mutation of the gene for sodium channel Nav1.7 is responsible for people to suffer from the chronic condition of primary erythromelalgia. Researchers have studied the DNA samples from 36 members of a same family in which 17 members suffer from the condition. The genetic mutation makes the pain sensing neurons to be hyper excited and trigger rapids signals even at lower than normal stimulating sensations.

Primary erythromelalgia is a disorder where the symptoms are intense burning pain felt in the hands and feet. The other symptoms of the condition are redness, sensations of heat, and swelling. Anything like standing, walking, exposure to heat may trigger an episode of sudden pain. An inherited condition, erythromelalgia may be only symptomatically treated.

Previous studies have identified two mutations in the gene coding for sodium channel Nav1.7 that is linked with erythromelalgia. The new study identifies the new mutation of the gene responsible. The identification of the mutations of the gene makes it easier to develop treatment for this condition which otherwise had no treatments.

Reference: Brain, July 2005
'"/>




Page: 1

Related medicine news :

1. Minor mutations in HIV virus
2. Genetic mutation to the fountain of youth discovered
3. Success of HIV may depend in its mutations
4. BRAC2 mutations is also linked with cancers in men
5. Familial Breast cancer without gene mutation not found to cause ovarian cancer.
6. Skin Cancer caused by mutations in a single Gene
7. H-ras gene mutation linked to Costello Syndrome
8. Autoimmune disorder caused due to mutation in cryopyrin protein
9. Uterine cancer may be associated with inherited mutations and a risk of many cancers
10. Special proteins to fight TB identified
11. A new growth factor identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Global law ... magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition are ... , Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their ... Award, an essay contest in which patients and their families pay tribute to a ... the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... Frederick, Maryland (PRWEB) , ... June 24, 2016 ... ... Mid-Atlantic Angels is actively feeding the Frederick area economy by obtaining investment capital ... support over the past 2½ years that have already resulted in more than ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has ... by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), ... Parenteral) - Global Forecast to 2021" report to ... The global pharmaceutical excipients market is projected to reach ... 6.1% in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, 2016 ... Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, the ... announced today online at www.diabetesscholars.org by the ... diabetes stand in the way of academic and community ... Foundation,s scholarship program since 2012, and continues to advocate ...
Breaking Medicine Technology: