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Gene glitches connecting pot with Schizophrenia

rgeted treatments to emerge for the illness.

It appears malfunctions in the brain's marijuana-linked circuitry may make one vulnerable to schizophrenia, Ujike said. This holds especially true for a condition called hebephrenic schizophrenia, which is marked by deterioration of personality, senseless laughter, disorganized thought and lack of motivation. These symptoms are similar to psychotic behavior sometimes triggered by severe cannabis abuse, which could mean the marijuana receptors in schizophrenics are far more active than they should be. Ujike stressed there is no evidence yet these genetic abnormalities can affect how the marijuana receptor actually acts in the brain.


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