Navigation Links
Gene glitches connecting pot with Schizophrenia

According to Japanese researchers, genetic abnormalities bound with marijuana-activated brain chemicals appear connected to schizophrenia. Hiroshi Ujike, a lead researcher, of the Okayama University, observed that this result supplies genetic evidence that marijuana// use can result in schizophrenia or a considerablelly increased risk of schizophrenia.

Schizophrenia is one of the greatest mental health challenges in the world, affecting roughly one of every 80 people and filling about a quarter of all hospital beds in the United States. For years, clinical scientists have known that abusing marijuana, also known as cannabis, can trigger hallucinations and delusions similar to symptoms often found in schizophrenia. Prior studies also show that cannabis used before age 20 raises the risk of schizophrenia six-fold.

According to the researchers, the hallucinogenic properties of marijuana, are connected to a biochemical found abundantly in the brain. The chemical, called cannabinoid receptor protein, studs the surfaces of brain cells and latches onto the active chemical within marijuana known as THC.

These sites are where marijuana acts on the brain.Ujike and his team examined the gene for the marijuana receptor in 115 Japanese patients with schizophrenia and an average age of 40.When they compared this gene in schizophrenics with the same gene in 130 normal men and woman of the same average age, they found distinct abnormalities in DNA sequences called nucleotides among the schizophrenics. Some of their nucleotides in the marijuana receptor gene appeared significantly more often than normal while others appeared less frequency.

Clinical neuroscientist, Carol Tamming at the University of Maryland, found that this was the first to report a potential abnormality of the cannabinoid system in schizophrenia. The importance of a finding here cannot be overstated, in that it would form a tissue target for drug development and allow ta rgeted treatments to emerge for the illness.

It appears malfunctions in the brain's marijuana-linked circuitry may make one vulnerable to schizophrenia, Ujike said. This holds especially true for a condition called hebephrenic schizophrenia, which is marked by deterioration of personality, senseless laughter, disorganized thought and lack of motivation. These symptoms are similar to psychotic behavior sometimes triggered by severe cannabis abuse, which could mean the marijuana receptors in schizophrenics are far more active than they should be. Ujike stressed there is no evidence yet these genetic abnormalities can affect how the marijuana receptor actually acts in the brain.


'"/>




Related medicine news :

1. Sex exploitation connected to Schizophrenia
2. Schizophrenia detected early
3. An insight about Schizophrenia
4. Risk Of Schizophrenia due to Gene Variation
5. Factors That Might Increase The Risk Of Schizophrenia
6. Identifying The Risks Of Developing Schizophrenia
7. Dads Age Found To Affect The Childs Risk for Schizophrenia
8. Famine May Be A Cause For Schizophrenia
9. Schizophrenia Gets A New Diagnostic Tool
10. Gene Activity connected to Schizophrenia
11. Prose Memory Deficits Found To Be Associated With Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: