Navigation Links
Gene glitches connecting pot with Schizophrenia

According to Japanese researchers, genetic abnormalities bound with marijuana-activated brain chemicals appear connected to schizophrenia. Hiroshi Ujike, a lead researcher, of the Okayama University, observed that this result supplies genetic evidence that marijuana// use can result in schizophrenia or a considerablelly increased risk of schizophrenia.

Schizophrenia is one of the greatest mental health challenges in the world, affecting roughly one of every 80 people and filling about a quarter of all hospital beds in the United States. For years, clinical scientists have known that abusing marijuana, also known as cannabis, can trigger hallucinations and delusions similar to symptoms often found in schizophrenia. Prior studies also show that cannabis used before age 20 raises the risk of schizophrenia six-fold.

According to the researchers, the hallucinogenic properties of marijuana, are connected to a biochemical found abundantly in the brain. The chemical, called cannabinoid receptor protein, studs the surfaces of brain cells and latches onto the active chemical within marijuana known as THC.

These sites are where marijuana acts on the brain.Ujike and his team examined the gene for the marijuana receptor in 115 Japanese patients with schizophrenia and an average age of 40.When they compared this gene in schizophrenics with the same gene in 130 normal men and woman of the same average age, they found distinct abnormalities in DNA sequences called nucleotides among the schizophrenics. Some of their nucleotides in the marijuana receptor gene appeared significantly more often than normal while others appeared less frequency.

Clinical neuroscientist, Carol Tamming at the University of Maryland, found that this was the first to report a potential abnormality of the cannabinoid system in schizophrenia. The importance of a finding here cannot be overstated, in that it would form a tissue target for drug development and allow ta rgeted treatments to emerge for the illness.

It appears malfunctions in the brain's marijuana-linked circuitry may make one vulnerable to schizophrenia, Ujike said. This holds especially true for a condition called hebephrenic schizophrenia, which is marked by deterioration of personality, senseless laughter, disorganized thought and lack of motivation. These symptoms are similar to psychotic behavior sometimes triggered by severe cannabis abuse, which could mean the marijuana receptors in schizophrenics are far more active than they should be. Ujike stressed there is no evidence yet these genetic abnormalities can affect how the marijuana receptor actually acts in the brain.


'"/>




Related medicine news :

1. Sex exploitation connected to Schizophrenia
2. Schizophrenia detected early
3. An insight about Schizophrenia
4. Risk Of Schizophrenia due to Gene Variation
5. Factors That Might Increase The Risk Of Schizophrenia
6. Identifying The Risks Of Developing Schizophrenia
7. Dads Age Found To Affect The Childs Risk for Schizophrenia
8. Famine May Be A Cause For Schizophrenia
9. Schizophrenia Gets A New Diagnostic Tool
10. Gene Activity connected to Schizophrenia
11. Prose Memory Deficits Found To Be Associated With Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... ... 2016 , ... A man who has struggled to quit smoking, a man who has struggled ... to find solutions to his problems – and he did. Now Nabat, a serial entrepreneur ... introduce his breakthrough inventions to the world and better people's lives. His own experience with ...
(Date:2/8/2016)... ... February 08, 2016 , ... The Bell Agency, a ... latest beneficiary of their ongoing community enrichment program. The current campaign fundraises for ... Donations are now being accepted at: http://www.angelsanddoves.com/donate.html . , Angels & Doves ...
(Date:2/8/2016)... ... February 08, 2016 , ... Eating disorders ... significant number of women and men with eating disorders report a history of ... predicts the development of an eating disorder. , At the 2016 iaedp ...
(Date:2/8/2016)... ... 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to a product ... from a cluster of melanin when exposed to sunlight. Although most moles are benign ... of embarrassment. Historically, mole removal has involved a painful, often expensive visit ...
(Date:2/7/2016)... ... February 07, 2016 , ... Women’s Excellence ... and the most minimally invasive approaches. , Women who have had multiple vaginal ... risk factors include surgery to the pelvic floor, connective tissue disorders, and obesity. ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... 2016 In a historic vote among its members this weekend, ... medical cannabis cultivation facility and dispensary on tribal land near ... as a provider for patients in the state,s Medical Cannabis Program. ... a provider for patients in the state,s Medical Cannabis Program. ... the project and pursue designation from the State of New ...
(Date:2/8/2016)... 2016 http://www.researchandmarkets.com/research/x6mkjm/knee ) has ... Devices Market by Product Type (Primary (Cemented & ... Canada, Eu-5, Japan, Bric, Turkey, Indonesia - Global ... their offering. --> http://www.researchandmarkets.com/research/x6mkjm/knee ) ... Reconstruction Devices Market by Product Type (Primary (Cemented ...
(Date:2/8/2016)... ARBOR, Mich. , Feb. 8, 2016  The ... Arbor announced today that, as part of ... become one of the first hospitals in the U.S. ... Karin Muraszko , M.D., U-M,s chair of neurosurgery. ... chair of neurosurgery. --> The BrightMatter ...
Breaking Medicine Technology: