Navigation Links
Gene enchances radiation therapy - A novel approach to fight cancer

In the era of fighting battle against cancer, researchers of Virginia have come out with a novel approach to execute the destiny. Radiation therapy is used to treat many types of cancer. An experimental form of gene therapy makes cancer cells more susceptible to radiation therapy.

Although radiation kills cancer cells, it has unwanted side effects that could counter its positive effects. Dr. Rupert K. Schmidt-Ullrich, of Virginia Commonwealth University in Richmond, and colleagues found that radiation activates the EGFR, or epidermal growth factor receptor, which is a part of a repair mechanism that can undo some of the destruction that radiation causes in cancer cells.//

The researchers in their experiment injected the mice with mutant form of EGFR, called EGFR-CD533 that prevents the repair mechanism in cancer cells from being activated by radiation and then they irradiated them. They found that the mice that had received the gene therapy had a nearly threefold decrease in activation of the EGFR repair system. They also found that tumor cells in the mice treated with the mutant gene were 46% less likely to survive than those in untreated mice.

The study shows that disrupting the EGFR system in cancer cells "can enhance the effectiveness of radiotherapy, a major treatment form for many cancers," Schmidt-Ullrich said.

Drs. Stephen P. Ethier and Theodore S. Lawrence, of the University of Michigan at Ann Arbor stated that such mutated gene therapy causing radiation boosting effects targeted against growth factor receptors offers an exciting potential advance in cancer treatment. This type of approach "offers the potential for a dramatic improvement in the outcome of treatment that, while not yet in our hands, is within our reach," they lamented. Hope this sooner gets into the application to humans to put an end to the cancer morbidiity and mortality.

Let us hope that future collaborations bet ween the Yale and University of Pennsylvania research teams will result in further understanding the disease.

"This is the future of how we will come to understand the pathology of diabetes."


'"/>




Related medicine news :

1. Antioxidants protect health tissue in people undergoing radiation therapy.
2. Low-radiation treatment for brain tumours
3. Lack of solar radiation causes cancer
4. Microwave radiation has no hazards
5. Rectal Cancer treated with radiation
6. Ways to counter radiation effects with new molecule discovery
7. Partial-Breast Irradiation an Unproven Therapy
8. New and easier method of radiation
9. Medulloblastoma Irradiation In Young Children Found To Impair IQ And Reading Skills
10. Apollo Hospital to collaborate with US cancer center to open new radiation therapy department
11. Risk of Thyroid cancer is increased after Childhood Irradiation of Neck region
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and Financial ... financial preparation services, is providing an update on a charitable event that began ... Rescue is a locally recognized nonprofit that provides shelter and care for animals ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... process to promote standards of excellence for the field of eating disorders, announces ... 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of ... part of a disaster drill on October 3rd. , Apple Rehab participated with the ... as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017   Divoti USA ... up to the standard of the latest FDA requirements, which stipulates ... Anyone in need of Medical ID jewelry such as ... Jewelry are engraved in terms of the new FDA ... Divoti offers this ...
(Date:10/11/2017)... 11, 2017  BioPharmX Corporation (NYSE MKT: BPMX) researchers ... an innovative way to use nonlinear optical imaging to ... new drugs. ... will show how researchers from BioPharmX and the Wellman ... used a suite of imaging techniques in what is ...
(Date:10/11/2017)... FRISCO, Texas , Oct. 11, 2017 /PRNewswire/ ... healthcare services, has amplified its effort during National ... patients about hereditary cancer risks. ... Journal of Clinical Oncology calculated that more than ... to have inherited mutations in BRCA1 or BRCA2 and ...
Breaking Medicine Technology: