Navigation Links
Gene causes moles to become cancerous

According to recent finding, researchers have identified a gene that causes benign moles on the skin to become cancerous. This could allow doctors to treat more effectively patients with early stages of melanoma.

A team of scientists lead by Dr. Rhoda Alani of Johns Hopkins University, found a gene known as Id1 that causes cancer cells to grow in melanoma. Id1 blocks a tumor suppressor gene that ordinarily keeps precancerous moles from progressing to melanoma or skin cancer.// The study found that high levels of the Id1 protein were expressed only in the first stages of melanoma when the disease lies on the surface of skin.

According to the American Cancer Society, patients who have melanoma that has not spread below the skin have a survival rate of 97 percent beyond five years. But as the tumor begins to grow, the survival rate falls to 50 percent if it has reached the lymph nodes below the skin and 20 percent if it has spread to other organs in the body. On a larger scale, this will be very useful in the early diagnosis and cure of the disease.

According to researchers a person's risk of melanoma is influenced by: * family history * exposure to the sun * number of moles *sensitivity of the skin Researchers studied Id1 protein levels in 21 human tissue samples including precancerous moles and various stages of melanoma. Accorind to Journal, diagnostic tools could be designed to monitor Id1 because it is only activated in early stages of melanoma, and not precancerous moles or later stages of the disease.

Id1 also may cause various mutations to occur in the cancer cells, making the suppressor gene damaged beyond repair. As the cancer grows, researchers reason, Id1 levels decrease because it is no longer needed to block the suppressor gene.

According to Alani a larger study of several hundred patients will be conducted in order to verify the Id1 gene's role in melanoma before designing a method to t est for it. This is important because the diagnosis of melanoma is very difficult and treatment varies based on the degree to which it has progressed. Physicians generally have a difficult time determining if a mole is cancerous. She feels that by developing a test to monitor for the presence of Id1, doctors will be able to better treat patients with the disease.

She said that Melanoma tumors spread very quickly, and the best treatment is to surgically remove the cancer because patients have not responded well to chemotherapy and radiation treatments.


'"/>




Related medicine news :

1. Lack of solar radiation causes cancer
2. Defective heart valve causes problems
3. Abortion made easy pill causes alarm in state
4. Research on causes for falling helps develop preventive strategies
5. Whiplash injury causes persistent
6. Study shows that interventions from health workers can bring about changes in asthma causes
7. Giving up smoking is good for health, but causes weight gain too
8. Prenatal exposure to air pollution causes chromosomal damage
9. Smoking during pregnancy causes reduced birthweight
10. Exposure to tobacco smoke causes genetic damage in fetus
11. Repeated checking causes memory distrust
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/26/2017)... ... April 26, 2017 , ... Intalere, the healthcare ... podcast, “Make Plans for MACRA,” highlighting the impact of the Medicare ... and how physicians and other clinicians are reimbursed for the care they deliver ...
(Date:4/26/2017)... ... April 26, 2017 , ... CareSet Labs today is releasing ... measured in Part D Medicare data. The dataset, called PaPR (Providers and Prescribing ... faxes or paper. The PaPR (pronounced "paper") data set aggregates this information ...
(Date:4/26/2017)... ... April 26, 2017 , ... The National Business Research Institute ... Registry of Emergency Medical Technicians and welcomes this organization to the NBRI ... G. West, Ph.D. , CEO & Organizational Psychologist at NBRI. “This award is ...
(Date:4/26/2017)... ... ... RawTrition now brings you BioEnergy which is a powder capsule whole food ... RawTrition is taking nutrients to the next level! The superfoods in RawTrition's BioEnergy ... (unlike the synthetically made options that are on the market). , Founder of RawTrition, ...
(Date:4/26/2017)... Doylestown, Pa. (PRWEB) , ... ... ... Solutions division, which provides an agile ecosystem and domain expertise for sponsors ... end-to-end, configurable randomization and trial supply management (RTSM) software platform. Bioclinica ...
Breaking Medicine News(10 mins):
(Date:4/24/2017)... UNION CITY, Calif. , April 24, 2017 /PRNewswire/ ... providing durability, grip, protection, and comfort, announces the release ... the Powerform S8+. This most recent example of leading ... high density grip pattern for 200% more tactile grip ... in user protection and durability. With TracTek and a ...
(Date:4/20/2017)... 20, 2017  Cogentix Medical, Inc. (NASDAQ: CGNT), ... the Urology, Uro/Gyn and Gynecology markets with innovative ... has joined the Company as Senior Vice President, ... position, Mr. Keswani will report directly to ... "Our organization is delighted that Ash has joined ...
(Date:4/20/2017)... DUBLIN , April 20, 2017 ... the "Global Biosimilar Pipeline and Market Prospects: Addressing ... report to their offering. ... "Global Biosimilar Pipeline and Market ... by Design" provides an in-depth assessment of the current ...
Breaking Medicine Technology: