Navigation Links
Gene causes moles to become cancerous

According to recent finding, researchers have identified a gene that causes benign moles on the skin to become cancerous. This could allow doctors to treat more effectively patients with early stages of melanoma.

A team of scientists lead by Dr. Rhoda Alani of Johns Hopkins University, found a gene known as Id1 that causes cancer cells to grow in melanoma. Id1 blocks a tumor suppressor gene that ordinarily keeps precancerous moles from progressing to melanoma or skin cancer.// The study found that high levels of the Id1 protein were expressed only in the first stages of melanoma when the disease lies on the surface of skin.

According to the American Cancer Society, patients who have melanoma that has not spread below the skin have a survival rate of 97 percent beyond five years. But as the tumor begins to grow, the survival rate falls to 50 percent if it has reached the lymph nodes below the skin and 20 percent if it has spread to other organs in the body. On a larger scale, this will be very useful in the early diagnosis and cure of the disease.

According to researchers a person's risk of melanoma is influenced by: * family history * exposure to the sun * number of moles *sensitivity of the skin Researchers studied Id1 protein levels in 21 human tissue samples including precancerous moles and various stages of melanoma. Accorind to Journal, diagnostic tools could be designed to monitor Id1 because it is only activated in early stages of melanoma, and not precancerous moles or later stages of the disease.

Id1 also may cause various mutations to occur in the cancer cells, making the suppressor gene damaged beyond repair. As the cancer grows, researchers reason, Id1 levels decrease because it is no longer needed to block the suppressor gene.

According to Alani a larger study of several hundred patients will be conducted in order to verify the Id1 gene's role in melanoma before designing a method to t est for it. This is important because the diagnosis of melanoma is very difficult and treatment varies based on the degree to which it has progressed. Physicians generally have a difficult time determining if a mole is cancerous. She feels that by developing a test to monitor for the presence of Id1, doctors will be able to better treat patients with the disease.

She said that Melanoma tumors spread very quickly, and the best treatment is to surgically remove the cancer because patients have not responded well to chemotherapy and radiation treatments.


'"/>




Related medicine news :

1. Lack of solar radiation causes cancer
2. Defective heart valve causes problems
3. Abortion made easy pill causes alarm in state
4. Research on causes for falling helps develop preventive strategies
5. Whiplash injury causes persistent
6. Study shows that interventions from health workers can bring about changes in asthma causes
7. Giving up smoking is good for health, but causes weight gain too
8. Prenatal exposure to air pollution causes chromosomal damage
9. Smoking during pregnancy causes reduced birthweight
10. Exposure to tobacco smoke causes genetic damage in fetus
11. Repeated checking causes memory distrust
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2017)... , ... January 20, 2017 , ... ... ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in a study indicating ... Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive Expiratory Pressure Devices ...
(Date:1/20/2017)... ... ... Christmas:” a beautiful and enchanting tale that teaches children the true meaning of Christmas. “Journey ... Oklahoma City, and a devoted woman of faith. , “Becoming a parent changes you. ... of my mind for years, but actually doing it might have been a while in ...
(Date:1/20/2017)... ... ... “The Land of More and More”: a brilliant story for children ... the simple and achievable answer. “The Land of More and More” is the creation ... in Angola, Indiana where he works with the children’s ministry department. , Michael ...
(Date:1/19/2017)... ... ... Today, the Centers for Medicare & Medicaid Services (CMS) announced over 359,000 clinicians ... Clinicians who participate in APMs are paid for the quality of care they give ... build a system that delivers better care and one in which clinicians work together ...
(Date:1/19/2017)... Los Angeles (PRWEB) , ... January 19, 2017 , ... ... Care Act will be repealed by Congressional political games that circumvent health needs of ... First Stand Rally” capture the human anxieties and needs government public servants were suppose ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 2017 Conference Call and Webcast to Follow ... it will release results for the fourth quarter of 2016 on ... ... call at 4:30 PM ET on Wednesday, February 15, 2017, during ... financial results and other corporate activities. To participate in the conference ...
(Date:1/19/2017)... BioTherapeutics Inc. ( Stealth ), a clinical-stage biopharmaceutical company ... additions to its senior leadership team: W. Douglas ... Daniel Geffken as interim Chief Financial Officer. In ... has been promoted to Chief Clinical Development Officer. ... Daniel to our management team, as both will be ...
(Date:1/19/2017)... 2017  Abaxis, Inc. (NasdaqGS: ABAX ), ... and consumables for the medical and veterinary markets worldwide, ... results for the third quarter fiscal year 2017, ended ... p.m. ET on Thursday, January 26, 2017.  The Company ... year 2017 after the market closes on Thursday, January ...
Breaking Medicine Technology: