Navigation Links
Gene Variation Associated With Better Mobility For Older Individuals

Research shows that elderly people who exercise regularly and have a certain gene variety have the tendency to have fewer problems in their movements than the people who lack the gene expression.

The research done by the scientists of Wake Forest University School of Medicine was published // in the latest issue of JAMA.

Mobility limitation (i.e., difficulty walking and climbing steps) is common and is strongly related to major health outcomes, and may represent a stage in the disablement process amenable to intervention, according to background information in the article.

The people reporting such difficulty in walking are at nearly 4 times the risk of nursing home placement and 3 times the risk of death over 2 years compared with those reporting no difficulty. In older adults, more physical activity is consistently associated with less functional decline.

Despite exercise’s general benefit, individual responses to exercise vary. The basis for this is unclear, but there appears to be a strong genetic component. A certain gene variation (an insertion [I]/deletion [D] polymorphism in intron 16 of the angiotensin-converting enzyme [ACE]) gene has been identified as a potential marker for differential response to exercise in younger adults.

The Health Aging and Body Composition (Health ABC) Cohort Study, conducted in the metropolitan areas of Memphis, Tenn., and Pittsburgh, Pa., included 3,075 well-functioning community-dwelling adults aged 70 through 79 years. The participants were enrolled from 1997 to 1998 and had an average follow-up of 4.1 years. Mobility limitation, which 1,204 participants developed, was defined as difficulty walking a quarter of a mile or walking up 10 steps, as reported on 2 consecutive semi-annual interviews.

The researchers report that in older well-functioning men and women, a high level of physical activity was associated with the preservation of physical function. Althoug h physical activity was associated with less mobility limitation for all ACE I/D genotypes, the improved risk benefit was significantly greater for those possessing the ID or DD genotypes compared with the II genotype. The physiological basis for these findings is uncertain. However, among the physically active participants, the II genotype was also associated with higher levels of total adiposity [body fat] and inter-muscular thigh fat.

Source: Newswise
'"/>




Related medicine news :

1. Variation in breast cancer
2. Risk Of Schizophrenia due to Gene Variation
3. Variations In ingredients From Brand to Brand
4. Tamoxifen Ineffective In Presence Of Genetic Variation in Breast Cancer
5. Seasonal Variation In Exercise And Eating Habits Identified
6. Genetic Variation In Bitter-Taste Receptor Gene Increases Alcoholic Risk
7. Gene Variations Raise the Risk of Childhood Cancer Survivors
8. Genetic Variations In Detoxifying Genes Lead To Lou Gehrigs diseases
9. Food Costs At Hospitals Show Mystifying Variations
10. Genetic Variation Linked to Age-Related Macular Degeneration
11. Stroke Risk Higher with Gene Variations
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/7/2018)... ... October 07, 2018 , ... Guruji Mahendra Trivedi is an ... at practical and spiritual levels. Founder of the Trivedi Effect®, Guruji Mahendra Trivedi ... inspired by Navratri, is a mystical time when Divine Energy is at its ...
(Date:10/5/2018)... ... October 05, 2018 , ... Ophthalmic Instruments, Inc. ... the 14th annual Major Rob Soltes Memorial Golf Tournament benefitting the Blinded Veterans ... held on Columbus Day, Monday, October 8th at Oak Creek Golf Club in ...
(Date:10/5/2018)... ... ... The American Orthopaedic Society for Sports Medicine ( AOSSM ) is proud to ... of the Sports Medicine Licensure Clarity Act (H.R.302) which was signed into law this ... protection for traveling team physicians and safeguards injured athletes’ timely access to the health ...
(Date:10/5/2018)... (PRWEB) , ... October 05, 2018 , ... ... Aimee Grimm, OD to its Tampa practice. Dr. Grimm specializes in comprehensive ... hybrid, scleral lenses, and corneal refractive therapy (CRT) lenses. Dr. Grimm treats patients ...
(Date:10/3/2018)... ... October 03, 2018 , ... ... solution provider, announces the release of IntelliMarket™ – a web-based tool that ... healthcare claims records. Using IntelliMarket™, healthcare strategy and marketing groups can quickly ...
Breaking Medicine News(10 mins):
(Date:10/3/2018)... ... 2018 , ... The Point of Grace Academy resides in rural Kisumu along ... highest levels of HIV/AIDS in all of Kenya. Also, while the school sits on ... heavy farm runoff, toxic chemicals, and algae blooms have rendered the water unsafe. ...
(Date:10/2/2018)... WEST MELBOURNE, Fla. (PRWEB) , ... October 02, ... ... are excited to announce the opening of The Refinery Medspa & Wellness, dedicated ... wellness treatments. , Grounded in science, The Refinery offers results-driven skin care ...
(Date:10/2/2018)... ... October 02, 2018 , ... The Honey Space for Moms is a ... for women in the community to meet the Honey Space for Moms team at ... Honey Space provides support groups for moms regarding work and life balance, miscarriage, adjusting ...
Breaking Medicine Technology: