Navigation Links
Gene Variation Associated With Better Mobility For Older Individuals

Research shows that elderly people who exercise regularly and have a certain gene variety have the tendency to have fewer problems in their movements than the people who lack the gene expression.

The research done by the scientists of Wake Forest University School of Medicine was published // in the latest issue of JAMA.

Mobility limitation (i.e., difficulty walking and climbing steps) is common and is strongly related to major health outcomes, and may represent a stage in the disablement process amenable to intervention, according to background information in the article.

The people reporting such difficulty in walking are at nearly 4 times the risk of nursing home placement and 3 times the risk of death over 2 years compared with those reporting no difficulty. In older adults, more physical activity is consistently associated with less functional decline.

Despite exercise’s general benefit, individual responses to exercise vary. The basis for this is unclear, but there appears to be a strong genetic component. A certain gene variation (an insertion [I]/deletion [D] polymorphism in intron 16 of the angiotensin-converting enzyme [ACE]) gene has been identified as a potential marker for differential response to exercise in younger adults.

The Health Aging and Body Composition (Health ABC) Cohort Study, conducted in the metropolitan areas of Memphis, Tenn., and Pittsburgh, Pa., included 3,075 well-functioning community-dwelling adults aged 70 through 79 years. The participants were enrolled from 1997 to 1998 and had an average follow-up of 4.1 years. Mobility limitation, which 1,204 participants developed, was defined as difficulty walking a quarter of a mile or walking up 10 steps, as reported on 2 consecutive semi-annual interviews.

The researchers report that in older well-functioning men and women, a high level of physical activity was associated with the preservation of physical function. Althoug h physical activity was associated with less mobility limitation for all ACE I/D genotypes, the improved risk benefit was significantly greater for those possessing the ID or DD genotypes compared with the II genotype. The physiological basis for these findings is uncertain. However, among the physically active participants, the II genotype was also associated with higher levels of total adiposity [body fat] and inter-muscular thigh fat.

Source: Newswise
'"/>




Related medicine news :

1. Variation in breast cancer
2. Risk Of Schizophrenia due to Gene Variation
3. Variations In ingredients From Brand to Brand
4. Tamoxifen Ineffective In Presence Of Genetic Variation in Breast Cancer
5. Seasonal Variation In Exercise And Eating Habits Identified
6. Genetic Variation In Bitter-Taste Receptor Gene Increases Alcoholic Risk
7. Gene Variations Raise the Risk of Childhood Cancer Survivors
8. Genetic Variations In Detoxifying Genes Lead To Lou Gehrigs diseases
9. Food Costs At Hospitals Show Mystifying Variations
10. Genetic Variation Linked to Age-Related Macular Degeneration
11. Stroke Risk Higher with Gene Variations
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2017)... FRANCISCO AND TEL AVIV (PRWEB) , ... June ... ... 3D-imaging sensor company whose technology makes it possible to see through objects, has ... challenging makers to create consumer apps with its fully programmable, Raspberry Pi-enabled 3D ...
(Date:6/28/2017)... ... 2017 , ... Drs. Steven Crandall, Karen Johnson and Kathy Lopez are now ... St. Clair, PA, without a referral. The doctors address jaw pain and ... joint and facial muscles that support it. , Jaw pain can be debilitating, ...
(Date:6/28/2017)... ... ... B. Sosin, a founding partner at the law firm Sosin, Arnold & Schoenbeck, ... the Illinois State Bar Association , in accordance with the organization’s rules of succession. ... a state-wide election and served in that capacity for the past year prior to his ...
(Date:6/28/2017)... ... 28, 2017 , ... Schneider Insurance and Financial, a Yellowstone ... southern Montana, is announcing a focused charity effort to gather regional support for ... by Zoo Montana provide students with current knowledge on the characteristics and behaviors ...
(Date:6/27/2017)... ... June 27, 2017 , ... Nearly 70 percent of ... released today by the American Society for Dermatologic Surgery (ASDS). , ... of consumers considering a cosmetic medical procedure has doubled since 2013. , “Cosmetic ...
Breaking Medicine News(10 mins):
(Date:6/5/2017)... 2017 Kohll,s Pharmacy & Homecare is the first distributor ... States . The Raizer is a simple battery operated ... to an almost-standing position within a few minutes. ... assistant and does not require any extra effort besides ... child can operate it, and lightweight and portable ...
(Date:5/30/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will present at the Goldman ... June 13, 2017, in Rancho Palos Verdes, California ... executive officer, is scheduled to present at 3:20 p.m. Pacific ... at http://ir.hill-rom.com/events.cfm . A recorded replay will be available ... 13, 2017. About ...
(Date:5/24/2017)... HAMPTON, Va. , May 24, 2017 /PRNewswire/ ... ivWatch Original Equipment Manufacturer (OEM) Board to enable ... technology with patient monitoring systems, infusion pumps and ... products, OEMs will be able to help health ... care and reduced risks related to IV therapy. ...
Breaking Medicine Technology: