Navigation Links
Gene Variation Associated With Better Mobility For Older Individuals

Research shows that elderly people who exercise regularly and have a certain gene variety have the tendency to have fewer problems in their movements than the people who lack the gene expression.

The research done by the scientists of Wake Forest University School of Medicine was published // in the latest issue of JAMA.

Mobility limitation (i.e., difficulty walking and climbing steps) is common and is strongly related to major health outcomes, and may represent a stage in the disablement process amenable to intervention, according to background information in the article.

The people reporting such difficulty in walking are at nearly 4 times the risk of nursing home placement and 3 times the risk of death over 2 years compared with those reporting no difficulty. In older adults, more physical activity is consistently associated with less functional decline.

Despite exercise’s general benefit, individual responses to exercise vary. The basis for this is unclear, but there appears to be a strong genetic component. A certain gene variation (an insertion [I]/deletion [D] polymorphism in intron 16 of the angiotensin-converting enzyme [ACE]) gene has been identified as a potential marker for differential response to exercise in younger adults.

The Health Aging and Body Composition (Health ABC) Cohort Study, conducted in the metropolitan areas of Memphis, Tenn., and Pittsburgh, Pa., included 3,075 well-functioning community-dwelling adults aged 70 through 79 years. The participants were enrolled from 1997 to 1998 and had an average follow-up of 4.1 years. Mobility limitation, which 1,204 participants developed, was defined as difficulty walking a quarter of a mile or walking up 10 steps, as reported on 2 consecutive semi-annual interviews.

The researchers report that in older well-functioning men and women, a high level of physical activity was associated with the preservation of physical function. Althoug h physical activity was associated with less mobility limitation for all ACE I/D genotypes, the improved risk benefit was significantly greater for those possessing the ID or DD genotypes compared with the II genotype. The physiological basis for these findings is uncertain. However, among the physically active participants, the II genotype was also associated with higher levels of total adiposity [body fat] and inter-muscular thigh fat.

Source: Newswise
'"/>




Related medicine news :

1. Variation in breast cancer
2. Risk Of Schizophrenia due to Gene Variation
3. Variations In ingredients From Brand to Brand
4. Tamoxifen Ineffective In Presence Of Genetic Variation in Breast Cancer
5. Seasonal Variation In Exercise And Eating Habits Identified
6. Genetic Variation In Bitter-Taste Receptor Gene Increases Alcoholic Risk
7. Gene Variations Raise the Risk of Childhood Cancer Survivors
8. Genetic Variations In Detoxifying Genes Lead To Lou Gehrigs diseases
9. Food Costs At Hospitals Show Mystifying Variations
10. Genetic Variation Linked to Age-Related Macular Degeneration
11. Stroke Risk Higher with Gene Variations
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2017)... ... January 20, 2017 , ... Michael and Betsy Brauser ... Cancer Institute. For Betsy, the clinical trial has been life-saving as she has ... worsened. , Betsy Brauser was diagnosed with ovarian cancer in 2009. She underwent ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Code Word: Chocolate Biscuit”: a biographical account following a man who ... the creation of published author, Marlyn Ivey, born in Lynn Haven, Florida and at the ... and at 19 years of age, he joined the Navy and got married right out ...
(Date:1/20/2017)... ... ... “Knowledge is God’s Lighthouse”: a moving and colorful collection of prayers that reminds ... published author, Gene Gaapf, a retired truck driver, and a long-time writer, whose published ... high school and have many different titles,” Gaapf mentions about his different works. “I ...
(Date:1/19/2017)... ... ... Next week after January 20th, the fear for many is that the humane ... of over 30 million. Many interviews with Dr. Carol Francis at the Los Angeles ... suppose to prioritize. Interviews provided below. , Among those present was Senator ...
(Date:1/19/2017)... ... January 19, 2017 , ... WhoHaha , a digital media ... American Heart Association (AHA) to produce a three-part video series that uses humor to ... part of the launch of AHA’s Healthy For Good™ movement, which is designed to ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... January 18, 2017 , , Marks E-QURE ... distribution agreement, following similar agreements in Israel ... Wound care is $2 5 billion ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment of ... Médica Equipos Médicos S.A.S. (TeckMedica) in Colombia for the ...
(Date:1/19/2017)... -- The Global Therapy Partnering Terms and Agreements since ... and agreements entered into by the world,s leading healthcare ... deals by value - Deals listed by company A-Z, ... report provides understanding and access to the partnering deals ... companies. The report provides an analysis of partnering ...
(Date:1/19/2017)... Jan. 18, 2017   Synthetic Biologics, Inc. ... developing therapeutics designed to preserve the microbiome to ... confirmed plans to initiate a Phase 2b/3 adaptive ... of lovastatin lactone designed to reduce methane production ... the gut to treat the underlying cause of ...
Breaking Medicine Technology: