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Gene Therapy Helps To Cure 'Incurable' Illness

k to make this technology available to all patients. Chronic granulomatous disorder (CGD) is a rare immunodeficiency disease caused by a defective gene on the maternally inherited X chromosome. In this condition their bodies cannot kill invading bacteria and fungi and they often have internal infections. Currently the disease is treated using bone-marrow transplants. The new technique involved the scientists to take blood stem cells from the men and introduced a healthy gene to the cells. The cells were then re-injected into the men. The key to the technique was a new, more efficient method of inserting the genes in many cells at the same time. Concern remains that such therapy could have a negative side effect like causing cancer of the blood. Research is continuing on how to make such techniques safer. Professor Adrian Thrasher of the Great Ormond Street Hospital in London says that further improvements and refinements in the technology are now being done and studied so as to maximise the effectiveness and safety of the system.
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