Navigation Links
Gene Therapy Helps To Cure 'Incurable' Illness

The immune systems of two men who were born with an "incurable" genetic disorder that made them almost defenceless against bacterial and fungal infections has been repaired with Gene therapy. // Sixteen months after an operation to repair a defective gene, the once severely ill patients show signs of complete recovery, a German-based team of scientists said Sunday. Scientists believe that this latest success will lead to further operations for treating other such chronic and incurable conditions due to inheritance of defective genes. These cutting-edge techniques have mainly been used in the past to help sick children. Dorothee von Laer, gene therapy coordinator at the Georg Speyer laboratory in Frankfurt, said two males, aged 25 and 26, had been treated for a hereditary autoimmune disease over the past two years at Frankfurt University Hospital. She said the new technique might prove suitable for other diseases where people are born with a defective gene. Gene therapy is a procedure involving the alteration of a person's genome to repair or replace a mutated gene. After years research, the technique has finally seems to have proven its potential with a handful of successful operations. The treatment of two men with chronic granulomatous disorder (CGD) is the latest success. The men suffered repeated life-threatening infections from bacteria and fungi from an early age had to rely on powerful antibiotics and antifungal medicines. After their operations 16 months ago, both patients have gained weight and have been free of the severe infections that have plagued them since childhood. Manual Grez of the Institute for Biomedical Research in Frankfurt, one of the leaders of the study published in the journal Nature Medicine, said the results suggest that it may be possible to use gene therapy to treat other similar inherited diseases. Stating that the work was a landmark study he said that though the results are very positive there still has to be a lot of wor k to make this technology available to all patients. Chronic granulomatous disorder (CGD) is a rare immunodeficiency disease caused by a defective gene on the maternally inherited X chromosome. In this condition their bodies cannot kill invading bacteria and fungi and they often have internal infections. Currently the disease is treated using bone-marrow transplants. The new technique involved the scientists to take blood stem cells from the men and introduced a healthy gene to the cells. The cells were then re-injected into the men. The key to the technique was a new, more efficient method of inserting the genes in many cells at the same time. Concern remains that such therapy could have a negative side effect like causing cancer of the blood. Research is continuing on how to make such techniques safer. Professor Adrian Thrasher of the Great Ormond Street Hospital in London says that further improvements and refinements in the technology are now being done and studied so as to maximise the effectiveness and safety of the system.
'"/>




Related medicine news :

1. Cancer Doctors Okays Controversial Prostate Therapy
2. Consensus on "Combination Therapy" for Breast Cancer
3. Gene Therapy shows promise in treating Hemophilia
4. "Make AIDS Therapy affordable" - Physicians demand
5. Hormone replacement Therapy a headache
6. Simple Therapy
7. Therapy for stopping the spread of cancer cells
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Letrozole Beats Tamoxifen in Breast Cancer Therapy
10. Garlic Supplements Impede HIV Therapy
11. Gene Therapy For Cystic Fibrosis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
(Date:6/24/2016)... Georgia (PRWEB) , ... June 24, 2016 , ... ... awards today at the Clinical Decision Making in Emergency Medicine conference in Ponte ... have authored journal articles published in Emergency Medicine Practice and Pediatric ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions today ... cultivation and processing operations at its production facility, and opened its first two ... the manufacturer of a complete system of proactive air and surface purification solutions ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone ... executive with extensive sequencing and genomics experience, as Vice President of North American Capital ... will be responsible for leading the sales team in the commercialization of the HTG ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 The Biotechnology industry ... to present great opportunities to investors. Stock-Callers.com assesses the ... Corp. (NYSE: XON ), Vertex Pharmaceuticals Inc. ... ARNA ), and Regeneron Pharmaceuticals Inc. (NASDAQ: ... and receive your complimentary trade alerts at: ...
(Date:6/23/2016)... SAN DIEGO , June 23, 2016 /PRNewswire/ ... advancing programs that address medical conditions resulting from ... that it has appointed Greg Doyle ... member of Leading BioSciences, executive management team and ... officer and chief financial officer. He will provide ...
(Date:6/23/2016)... , June 23, 2016 Research ... Distribution in Europe 2016 Edition: The New Global Agenda " ... OTC Distribution in Europe ... that explores and tracks change. It identifies the driving factors ... for the consumer healthcare industry now and in the future. ...
Breaking Medicine Technology: