Navigation Links
Gene Test to Spot Adults Who Might Get Diabetes

A set of genes that appear to raise the risk of adult-onset diabetes has been identified, promising a test that can predict// who is likely to develop the disease.

An international team of scientists has identified five different genetic variants that are linked to the condition, which is caused both by family inheritance and lifestyle factors such as poor diet, obesity and smoking. The five variants are thought together to account for about 70 per cent of the genetic risk of type 2 diabetes, the form of the disease that generally strikes in adulthood.

The findings are important as they pave the way for a blood test that could be used to identify people who are predisposed to developing diabetes.

Such a test could be used in a screening programme to pick up those who are most at risk, who could then alter their diet and exercise patterns accordingly. Professor Philippe Froguel of Imperial College, London, one of the leaders of the study, said: 'The two major reasons why people develop type 2 diabetes are obesity and a family link. Our new findings mean that we can create a good genetic test to predict people’s risk of developing this type of diabetes.

'If we can tell someone that their genetics mean they are predisposed towards type 2 diabetes, they will be much more motivated to change things such as their diet to reduce their chances of developing the disorder.'

The results, which are published in the journal Nature, also point towards at least one potential cause of the disease.

One of the five genes, SLC30A8, is involved in transporting the mineral zinc in the body, and is known to be involved in secreting insulin, a hormone that is important to metabolising sugar.

As type 2 diabetes is associated with an insulin deficiency, it could be possible to treat it by fixing the faulty zinc transporter. 'We can also use what we know about the specific genetic mutations associated with t ype2 diabetes to develop better treatments,' Professor Froguel said.

Diabetes, which affects at least two million people in Britain comes in two forms. In type 1, which accounts for between 5 per cent and 15 per cent of cases and usually starts in childhood, the body cannot make insulin at all, and regular injections of the hormone are needed.

Type 2 diabetes is much more common, accounting for between 85 per cent and 95 per cent of cases, and generally begins after the age of 40. While the body still makes some insulin, it either does not make enough, or the body becomes resistant to its effects.

It is usually linked to obesity, though a family history of the condition is also known to raise the risk. It is not normally treatable with insulin injections or other drugs, and must usually be controlled by switching to a healthier diet or by losing weight.

This is indeed a very important discovery. Since there have been friends who were not obese, who did not smoke and followed a healthy diet and still developed type 2 diabetes, the genetic factor is the probable explanation. A thank you to the scientists working on this project.

Source-Bio-Bio Technology
'"/>




Related medicine news :

1. The Key To Prevention Of Heart Disease In Adults
2. The Harmful Effects Of Stress in Young Adults
3. Obese Adults Undergo Less Medical Tests And More Vulnerable To Diseases
4. New Drug Found To Improve Driving Performance In Young Adults With ADHD
5. Neglect In Childhood Could Cause Abnormal Behaviour In Adults
6. Wounds Heal 25% Faster In Older Adults Who Exercise Regularly
7. After Cardiac Arrest, Children Fare Better Than Adults
8. Older Adults Get Distracted More Easily
9. Bird-Flu: A Child and Two Adults, Quarantined At Jalgaon
10. Link Between Pesticides And Cancer Minimal For Adults
11. Dissatisfied Marriage Have a Bad Effect on the Health of Older Adults
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical ... the "Company"), which develops, markets and sells medical devices ... , signed a strategic cooperation agreement with Hongyuan ... "Hongyuan Supply Chain") on June 20, 2016, to develop ... the strategic cooperation agreement, Dehaier will leverage Hongyuan Supply ...
Breaking Medicine Technology: