Navigation Links
Gene Test Shown to Measure Heart Function After Transplant

New research suggests a genomic test may provide detailed information on how well a transplanted heart is performing.// The gene expression profiling (GEP) test, known as the Allomap test, is currently used to detect the absence of heart transplant rejection instead of routine invasive heart muscle biopsies, but has now been shown to correlate with oxygen saturation levels, the pressure in the heart before pumping, and the electrical properties of the transplanted heart. These measures are crucial to understanding how well the transplanted heart is functioning.

The research was presented, at the American College of Cardiology’s 56th Annual Scientific Session in New Orleans. The presentation is based on preliminary data on 80 patients who received the GEP test. Physicians hope to confirm these results in future studies.

“Understanding how the GEP score differentiates heart transplant function may provide a valuable tool to help tailor therapies to meet the specific needs of each heart transplant patient,” said Dr. Deng.

Until recently, following a heart transplant, patients had to go through invasive heart-muscle biopsies to check for organ rejection. The GEP test is a non-invasive alternative that provides a molecular score measuring the body’s immune response to the heart transplant. A below-threshold test score identifies transplant patients who are at very low risk for rejecting their transplanted hearts and who can be monitored and managed using noninvasive methods such as the GEP test. Those patients may benefit from being more aggressively weaned off intensive immunosuppressive regimens. This new research suggests that the use of this test may have much greater potential than simply identifying patients without rejection.

Approximately 30 percent of all heart transplant patients reject their new heart at least once in the first year after transplantation. Transplant patients are then treated with anti-reject ion medications, which increase the potential for medication side effects.

The GEP test is covered by Medicare and is available to heart transplant patients, ages 15 and older, after two months post-transplantation.

Source-Newswise
RM
'"/>




Related medicine news :

1. Link Shown Between Military Service And Risk For ALS
2. Poor Preventive Measures Taken By Diabetics
3. Study On Self Measurement Of Blood Pressure
4. Diabetics Should Adopt Better Preventive Measures
5. Experts Recommend Preventive Measures For Avian Flu To Begin From Farms
6. Bird Flu: Orissa Initiates Protective Measures
7. Germany Institutes Tough Measures To Tackle Bird Flu
8. LDH Measurement Can Predict Outlook Of Patients With SCD
9. Protection Measures against Elder Abuse
10. Pakistan Enforces Strict Bird Flu Measures, Poultry Import Banned
11. Novel Metal Detector To Measure Zinc Level In Humans
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users ... - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 ... Pro X . Simply select a ProHand generator and drag it above media or ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
Breaking Medicine Technology: