Navigation Links
Gene Mutation Linked With Risks of Stroke

A Danish study shows that if you happen to posses a certain gene mutation, your risks of getting a stroke// double.

The gene in question is a specific variation for hereditary hemochromatosis. This is an autosomal recessive disease associated with increased iron accumulation, which affects how the body metabolizes iron, which results an iron build-up in the liver.

Without treatment, the condition causes liver enlargement that can lead to cirrhosis or liver cancer. The disease can also cause diabetes, heart disease, arthritis, and other serious conditions.

The study focused on two variations in the hemochromatosis gene - H63D and C282Y.

The report published the journal Neurology, says that of all the various combinations of these mutations, only patients with two copies of H63D were found to have a significantly increased risk of cerebrovascular disease and ischemic stroke (a stroke caused by a blockage in an artery in the brain, which cuts off the blood supply).

Says senior author Borge G. Nordestgaard, from Herlev University Hospital: “This type of gene has previously been associated with brain diseases such as Alzheimer's disease, Parkinson disease, ALS, multiple sclerosis, and cerebrovascular disease, but this is the first time we've been able to determine this gene predicts such a significant increased risk of stroke".

The researchers followed the health of 9,178 people over 24 years. Of the sample 393 had a stroke during that time. Those with a particular mutation to the HFE gene (also known as the haemochromatosis gene) were found to be two to three times more likely to develop the condition.

Yet, the researchers do not know how this genetic defect, which is carried by about a quarter of people in northern Europe, might cause a stroke. They agree that its involvement may give researchers new leads for understanding and preventing strokes as well as the potential for genetic tests to predict who is most at risk.

Strokes are the leading cause of disability in the UK and the third most common cause of death after cancer and heart disease. Smoking, obesity, excessive alcohol intake, lacks of exercise, diabetes, high blood cholesterol and high blood pressure is all known to increase the risk.
ANN
'"/>




Related medicine news :

1. Mutation connected to Osteoporosis
2. Stem Cells Have Few Mutations
3. Gene Mutation Causes Ovarian Failure
4. Mutations in NOTCH1 cause an early developmental defect in the aortic valve
5. A Word Of Caution: Routine Screening For Breast Cancer Mutation Not Advisdable
6. Coffee Reduces Risk of Breast Cancer in BRCA1 Mutation Carriers
7. CCR5 Mutation Confers Immunity Against HIV But Not Against West Nile Virus Illness
8. Wound Healing Accelerated By Mutation In Deafness Gene
9. No Mutation Of Bird Flu Virus: WHO
10. Gene Mutation May Influence Age at Onset of Parkinsons Disease
11. Menin Gene Mutation made Insulin Secreting Cells to Proliferate
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson ... offers insurance and financial preparation services, is providing an update on a charitable ... , Rock City Rescue is a locally recognized nonprofit that provides shelter and ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
Breaking Medicine Technology: