Navigation Links
Gene Mutation Linked With Risks of Stroke

A Danish study shows that if you happen to posses a certain gene mutation, your risks of getting a stroke// double.

The gene in question is a specific variation for hereditary hemochromatosis. This is an autosomal recessive disease associated with increased iron accumulation, which affects how the body metabolizes iron, which results an iron build-up in the liver.

Without treatment, the condition causes liver enlargement that can lead to cirrhosis or liver cancer. The disease can also cause diabetes, heart disease, arthritis, and other serious conditions.

The study focused on two variations in the hemochromatosis gene - H63D and C282Y.

The report published the journal Neurology, says that of all the various combinations of these mutations, only patients with two copies of H63D were found to have a significantly increased risk of cerebrovascular disease and ischemic stroke (a stroke caused by a blockage in an artery in the brain, which cuts off the blood supply).

Says senior author Borge G. Nordestgaard, from Herlev University Hospital: “This type of gene has previously been associated with brain diseases such as Alzheimer's disease, Parkinson disease, ALS, multiple sclerosis, and cerebrovascular disease, but this is the first time we've been able to determine this gene predicts such a significant increased risk of stroke".

The researchers followed the health of 9,178 people over 24 years. Of the sample 393 had a stroke during that time. Those with a particular mutation to the HFE gene (also known as the haemochromatosis gene) were found to be two to three times more likely to develop the condition.

Yet, the researchers do not know how this genetic defect, which is carried by about a quarter of people in northern Europe, might cause a stroke. They agree that its involvement may give researchers new leads for understanding and preventing strokes as well as the potential for genetic tests to predict who is most at risk.

Strokes are the leading cause of disability in the UK and the third most common cause of death after cancer and heart disease. Smoking, obesity, excessive alcohol intake, lacks of exercise, diabetes, high blood cholesterol and high blood pressure is all known to increase the risk.
ANN
'"/>




Related medicine news :

1. Mutation connected to Osteoporosis
2. Stem Cells Have Few Mutations
3. Gene Mutation Causes Ovarian Failure
4. Mutations in NOTCH1 cause an early developmental defect in the aortic valve
5. A Word Of Caution: Routine Screening For Breast Cancer Mutation Not Advisdable
6. Coffee Reduces Risk of Breast Cancer in BRCA1 Mutation Carriers
7. CCR5 Mutation Confers Immunity Against HIV But Not Against West Nile Virus Illness
8. Wound Healing Accelerated By Mutation In Deafness Gene
9. No Mutation Of Bird Flu Virus: WHO
10. Gene Mutation May Influence Age at Onset of Parkinsons Disease
11. Menin Gene Mutation made Insulin Secreting Cells to Proliferate
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, ... journal articles published in Emergency Medicine Practice and Pediatric Emergency Medicine ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data derived ... Assessment of major trends with potential impact on the market ... of market segmentation which comprises of sub markets, regional and ...
Breaking Medicine Technology: