Navigation Links
Gene May Regulate Cellular Aging

ounger animals.' In mice with an excess of p16INK4a, 'islet cells aged prematurely; they stopped dividing early.' 'This suggests that if we could attenuate p16INK4a expression in some way in humans, it could lead to enhanced islet re-growth in adults and a possible new treatment for diabetes,' Sharpless said.

Similar results were found in the other studies, which focused on brain stem cells and blood stem cells.

The Michigan researchers, led by Dr. Sean Morrison, examined the role played by p16INK4a in neural stem cells, progenitor cells that can form new neurons and other brain cells. The team showed that p16INK4a increases markedly in those cells with aging. Moreover, p16INK4a -deficient neural stem cells work better and don't age to the same extent that wild-type (normal) stem cells do, Sharpless said.

Dr. Janakiraman Krishnamurthy, lead author of the UNC study and a postdoctoral scientist in the Sharpless lab, was a co-author of the Michigan report. The Harvard team, led by Dr. David Scadden, studied the role of p16INK4a in hematopoietic stem cells, which proliferate continuously during the adult lifespan and produce massive amounts of new blood cells on an hourly basis. Their results suggest that p16INK4a is the molecular basis for an old-age 'signal' previously observed in blood stem cells. The Harvard study also showed that blood stem cells from old mice lacking p16INK4a functioned better than old cells from wild-type mice, suggesting p16INK4a causes aging of these cells as well.

Sharpless cautions that any promise of a potential new aging treatment based on p16INK4a should include two important caveats. 'First, even though old mice lacking p16INK4a show enhanced stem cell function, they do not live longer. This is because p16INK4a is an important cancer-suppressor gene, and mice lacking p16INK4a develop more cancers than old, normal mice,' he said.

'Secondly, in all three studies, p16INK4a l
'"/>




Page: 1 2 3

Related medicine news :

1. Brain Enzyme Found To Regulate Weight
2. Chemical Signaling Helps Regulate Sensory Map Formation In The Brain
3. Researchers Purify Protein That Could Regulate Male Hormones
4. Ayurveda Massage Centres in Kerala to be Regulated
5. A Protein In Brain Regulates Anxiety And The Consumption Of Alcohol
6. Study States That CNS Could Regulate Arthritis
7. Gene Involved In Common Birth Defect Also Regulates Skin Biology
8. A New System To Regulate Use Of Chemicals
9. Screening by Private Companies Must Be Regulated: NSC
10. Tobacco Control Laws to Be Regulated in India
11. Use of Cellular Phones associated with Increased risk of Brain Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene May Regulate Cellular Aging

(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company ... to follow it on Facebook, Twitter, and Pinterest. The fans ... Angelweddingdress draws a lottery every week. , Moreover, the company ... 2015. Click Angelweddingdress homepage for more information. ...
(Date:1/22/2015)... York (PRWEB) January 22, 2015 The federal ... in the U.S. District Court, Southern District of West Virginia ... Inc. in that proceeding’s first bellwether trial. In an Order ... a new trial after finding that C.R. Bard had not ...
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo ... the federal multidistrict litigation underway in U.S. District Court, ... an Order dated January 20th, the Court has remanded ...
(Date:1/22/2015)... 2015 Carinsurancesavings.biz has released a new blog ... dismemberment insurance . , Purchasing an accidental death and ... advantageous. This type of rider provides benefits if the insured ... considered a lesser form of life insurance. , AD&D ...
(Date:1/22/2015)... 22, 2015 Yesterday, Senator Holly ... and Kristin Olsen (R-Modesto) were honored by the ... advancing biotechnology, biomedical science, medical device and pharmaceutical ... received the “2014 Life Sciences Champion” award from ...
Breaking Medicine News(10 mins):Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3
... Understanding Not Confusion, FOLSOM, Calif., Feb. 20 ... California Walnut Commission: Given the state of the,national waistline, ... is clear. We welcome new independent nutrition rating systems,that ... While some fear,that this will be confusing, our research ...
... Health Solutions study finds anxiety over financial, preparedness; consumers ... ... presidential election, WASHINGTON, Feb. 20 American consumers want ... online,connection to health care providers and medical records, customized,insurance coverage and ...
... Latest procedures and techniques discussed at surgeons, conference, ... Achilles,tendon surgery patients are getting back on their ... The introduction of tissue graft products, bone anchors, ... with,less invasive treatments and speedier recovery times. More ...
... Feb. 20 Varian Medical,Systems (NYSE: VAR ... about,its revolutionary RapidArc(TM) radiotherapy technology for faster and ... opportunity,to learn more about a technology that makes ... two to eight,times faster than is possible with ...
... 012,Smile.Communications (Nasdaq: SMLC ) today announced ... Tuesday , February 26, 2008, before the,market is ... an interactive,teleconference to discuss the results at 09:00 ... following access numbers several minutes before the,call begins: ...
... The American Cancer Societys annual cancer statistics report finds that ... by 18.4 percent among men and by 10.5 percent among ... 1990s, which translates to the avoidance of more than half ... Society epidemiologists predict that in the U.S. in 2008 there ...
Cached Medicine News:Health News:Walnuts Rank High on New Nutrition Scales 2Health News:Walnuts Rank High on New Nutrition Scales 3Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 2Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 3Health News:Groundbreaking Deloitte Survey Reveals Many U.S. Consumers Want Major Changes in Health Care Design, Delivery 4Health News:Achilles Tendon Surgery Advances Speed Recovery 2Health News:Varian Medical Systems Announces Symposia on RapidArc Technology for Faster, More Precise Radiotherapy Treatments 2Health News:Varian Medical Systems Announces Symposia on RapidArc Technology for Faster, More Precise Radiotherapy Treatments 3Health News:012 Smile.Communication's Fourth Quarter Earnings Release and Conference Call Scheduled for February 26, 2008 2Health News:012 Smile.Communication's Fourth Quarter Earnings Release and Conference Call Scheduled for February 26, 2008 3Health News:Report says half a million cancer deaths have been averted since death rate drop 2Health News:Report says half a million cancer deaths have been averted since death rate drop 3Health News:Report says half a million cancer deaths have been averted since death rate drop 4Health News:Report says half a million cancer deaths have been averted since death rate drop 5
(Date:1/23/2015)... Inc. (ICBU) has repositioned itself as a holding company with ... in the hydroponic, hemp and medical marijuana sectors. By acquiring ... sector, and recently partnering with the Chippewa Tribe Nation to ... iMD is committing to bring its vision to the market ...
(Date:1/23/2015)... Jan. 23, 2015 Cord Blood America, Inc. ( www.cordblood-america.com ... the "Company")  filed a Preliminary Proxy Statement, Schedule 14A, with ... and provides an update for shareholders detailing why a "YES" ... Dear Shareholders, As we reflect upon ...
(Date:1/23/2015)... , Jan. 23, 2015  CytoSorbents Corporation (NASDAQ CM: ... CytoSorb® extracorporeal cytokine adsorber to reduce deadly inflammation ... receipt of $385,642, net of transaction costs, in ... Technology Business Tax Certificate Transfer Program sponsored by ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3
The flexible EXXCEL ePTFE Vascular Access Graft material is designed to offer textile-like handling characteristics-cuts neatly for a clean edge, retains fully open lumen shape, and sutures smoothly....
... intended for monitoring the accuracy and precision of ... in vitro diagnostic use only. Provided in a ... up to ten days stability at 2 ... used in accordance with the directions accompanying the ...
PowerMed is a billing software....
Managed care is a billing and tracking system....
Medicine Products: