Navigation Links
Gene May Regulate Cellular Aging

ounger animals.' In mice with an excess of p16INK4a, 'islet cells aged prematurely; they stopped dividing early.' 'This suggests that if we could attenuate p16INK4a expression in some way in humans, it could lead to enhanced islet re-growth in adults and a possible new treatment for diabetes,' Sharpless said.

Similar results were found in the other studies, which focused on brain stem cells and blood stem cells.

The Michigan researchers, led by Dr. Sean Morrison, examined the role played by p16INK4a in neural stem cells, progenitor cells that can form new neurons and other brain cells. The team showed that p16INK4a increases markedly in those cells with aging. Moreover, p16INK4a -deficient neural stem cells work better and don't age to the same extent that wild-type (normal) stem cells do, Sharpless said.

Dr. Janakiraman Krishnamurthy, lead author of the UNC study and a postdoctoral scientist in the Sharpless lab, was a co-author of the Michigan report. The Harvard team, led by Dr. David Scadden, studied the role of p16INK4a in hematopoietic stem cells, which proliferate continuously during the adult lifespan and produce massive amounts of new blood cells on an hourly basis. Their results suggest that p16INK4a is the molecular basis for an old-age 'signal' previously observed in blood stem cells. The Harvard study also showed that blood stem cells from old mice lacking p16INK4a functioned better than old cells from wild-type mice, suggesting p16INK4a causes aging of these cells as well.

Sharpless cautions that any promise of a potential new aging treatment based on p16INK4a should include two important caveats. 'First, even though old mice lacking p16INK4a show enhanced stem cell function, they do not live longer. This is because p16INK4a is an important cancer-suppressor gene, and mice lacking p16INK4a develop more cancers than old, normal mice,' he said.

'Secondly, in all three studies, p16INK4a l
'"/>




Page: 1 2 3

Related medicine news :

1. Brain Enzyme Found To Regulate Weight
2. Chemical Signaling Helps Regulate Sensory Map Formation In The Brain
3. Researchers Purify Protein That Could Regulate Male Hormones
4. Ayurveda Massage Centres in Kerala to be Regulated
5. A Protein In Brain Regulates Anxiety And The Consumption Of Alcohol
6. Study States That CNS Could Regulate Arthritis
7. Gene Involved In Common Birth Defect Also Regulates Skin Biology
8. A New System To Regulate Use Of Chemicals
9. Screening by Private Companies Must Be Regulated: NSC
10. Tobacco Control Laws to Be Regulated in India
11. Use of Cellular Phones associated with Increased risk of Brain Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene May Regulate Cellular Aging

(Date:8/20/2014)... August 20, 2014 With 3943.8% growth, Connexion ... of the nation’s fastest growing companies. The Inc. 500 ranks ... care sector. Connexion Point is the #1 fastest growing company ... Medicare and Medicaid, and its clients include four of the ... employs 1,000 people and has offices and contact centers in ...
(Date:8/20/2014)... a novel approach to treating cancer - using Botox. ... Science Translational Medicine shows that cancer growth ... nerves that are linked to cancer stem cells. The ... made the treatment cheap, safe and efficient. The researchers ... will soon start testing on humans. , The nervous ...
(Date:8/20/2014)... of endophthalmitis, a potentially blinding condition that can occur ... the well-known staphylococci ("staph") and streptococci ... in the August issue of Ophthalmology and ... at New York Eye and Ear Infirmary of Mount ... gram-positive bacteria, which include staph and strep infections, accounted ...
(Date:8/20/2014)... A common approach to treating kidney ... not improve survival chances for people who suddenly developed ... the University of Pittsburgh School of Medicine. ... journal PLOS One , suggest acute hemodialysis, an ... sudden kidney failure, may not provide a definitive benefit ...
(Date:8/20/2014)... UK (PRWEB) August 20, 2014 The ... to increase considerably in the offing across the top ... as of 2013 to around USD 8 billion by ... period. The growth is projected to be driven by ... which is currently lacking efficient treatment, unlike the non-squamous ...
Breaking Medicine News(10 mins):Health News:With 3943.8% Growth, Connexion Point, a Leader in Contact Centers for Health Care, Ranks 86th on the Inc. 500 List as One of the Nation’s Fastest Growing Companies 2Health News:Treating gastric cancer -- with Botox 2Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 2Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 3Health News:Pitt Analysis Questions Use of Acute Hemodialysis Treatment 2Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 2Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 3Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 4
... kill cervical cancer cells missed by chemotherapy , , TUESDAY, ... Avastin to radiation and chemotherapy improves results for patients ... mifepristone (RU-486, the so-called abortion pill) to chemotherapy kills ... are the conclusions of two reports on new trends ...
... OrthoSynetics(TM), the largest,provider of business services to orthodontic ... by hiring four new team members with,extensive experience ... year, we have bolstered our leadership team and,infrastructure ... said Chris Roussos, president and CEO of OrthoSynetics. ...
... Primary Less Than One Week Away, AARP Members,Gather ... They Debate,In Philadelphia., PHILADELPHIA, April 15 ... primary vote, the nation will be,watching Sen. Barack ... for,the Democratic Party,s presidential nomination during a debate ...
... Va., April 15 The American,Chemistry Council (ACC) ... Toxicology Program,s (NTP) Center for the Evaluation of,Risks ... last year,yesterday,s release of the draft NTP Brief ... or high level concerns for adverse effects of,bisphenol ...
... colon cancer, premature aging poses worries for manned missions ... -- Astronauts may be at increased risk of colon ... in space, a new report says. , The study, ... for Cancer Research annual meeting in San Diego, has ...
... tumors may be a factor, experts suggest, , , TUESDAY, ... of breast cancer dropped dramatically after millions of American ... doesn,t seem to have benefited black women. ... stayed essentially the same for black women from 2002 ...
Cached Medicine News:Health News:Extra Drug Improves Rectal Cancer Treatment 2Health News:Extra Drug Improves Rectal Cancer Treatment 3Health News:OrthoSynetics(TM) Expands Sales Team; Prepares to Grow 2Health News:AARP to Host Discussion and Debate Watch Event 2Health News:AARP to Host Discussion and Debate Watch Event 3Health News:Draft National Toxicology Program Report Supports Safety of Bisphenol A 2Health News: Space Radiation a Risk for Astronauts 2Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 2Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 3
(Date:8/20/2014)... 20, 2014 Reportlinker.com announces that ... in its catalogue: Personal Accident ... and Opportunities to 2017 ... The report provides in depth market analysis, ... accident and health insurance segment, including: • ...
(Date:8/20/2014)... , Aug. 20, 2014 The National Necrotizing ... Fernando Davila has been successfully treated for a life ... Dr, Anibal R. Gauto , Medical Director of Inpatient ... Eisenhower Medical Center in Rancho Mirage, California ... pioneered by Dr. John Crew at Seton Hospital ...
(Date:8/20/2014)... 20, 2014   Ventana Medical Systems, Inc. ... announced that its VENTANA System for Primary Diagnosis ... European Union for routine pathology, including primary diagnosis ... VENTANA Virtuoso software coupled with either the VENTANA ... scanner, provides automated digital slide creation, case management ...
Breaking Medicine Technology:Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 2Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 3Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 4Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 5Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 6Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3
... Md., July 26, 2011 Vapotherm announced today ... device developed specifically for homecare and other low ... the U.S. and European markets. ... patients in home and other extended care environments. ...
... July 26, 2011 Patients at Resurrection Medical Center (RMC), ... now receive non-invasive, whole-body PET/CT scans in just minutes. The ... in the world, the new 128-slice PET/CT scanner is a ... imaging techniques within a single machine. The ...
Cached Medicine Technology:Vapotherm Announces Commercial Launch of Flowrest® Homecare Device 2Resurrection Medical Center First in Chicago - 8th in the World - to Offer 128-Slice PET/CT Scanner Technology 2
... drying system, 220-240 V, includes Model 583 gel ... 583 gel dryer is a vacuum-based gel dryer ... cm with variable temperature control and three preprogrammed ... vacuum pump used for pulling vacuum on gel ...
... system utilizes a hot air drying device for ... to four drying frames at once. Gels are ... viewing. The assembly table is recessed to provide ... frame. This 230 V, 50 Hz system includes ...
The GelAir™ dryer is a component of the GelAir drying system. Supplied as a 115 V, 60 Hz gel drying oven....
... voltage power supply, the 105 is very simple ... switch control the output, which is variable in ... two-position switch toggles the bright LED display from ... is equipped with an over current detector for ...
Medicine Products: