Navigation Links
Gene Fusion Test to screen children’s with Acute Lymphoblastic Leukemi

Dr Moorman and his colleagues from Southampton University have found a new gene based test for identifying DNA fusion, in which DNA of two or more genes fuse. The research team is focusing on detection of genes // linked to the most common form of childhood leukemia, which is called as Acute Lymphoblastic Leukemia (ALL). The researchers took more than 6 years to develop this genetic test. The treatment is given by chemotherapy which kills the leukemia cells and allows the bone marrow to produce non cancerous cells.

Chemotherapy can get rid of the leukaemia cells in about three-quarters of people with ALL, putting them into disease remission. This new gene test helps to detect more resistant and serious ALL disease which helps to provide more effective and specialised treatment options. The gene test detects gene fusion of gene etv6 with runx1, bcr joining with abl and a gene called mill that can fuse with several different partners.

A complete epidemiological study involving more than By looking at more than 1,000 children’s with ALL were screened for gene fusion and found the pattern and type of gene fusion predicted the severity and prognosis to treatment. Children’s with fusion of etv6 with runx 1 - about 20% of children with ALL - had better outcomes than others. Those with multiple copies of runx 1 had some of the poorest outcomes.

"It's an important confirmatory test to the traditional method of cytogenetics, which looks at chromosome numbers and structure.”As a result of our work, doctors now use these three gene fusion tests as standard and will treat their patient accordingly,” said Dr. Mooran.
'"/>




Page: 1

Related medicine news :

1. A sunscreen from the sea
2. Need for Colon cancer screening
3. DNA biochip for genetic screening
4. Breast screening among diabetic women
5. Fast screening for macular degeneration
6. Inadequate proof to justify routine prostate screen
7. New virtual colonoscopy procedure for easier colon screening
8. Hearing loss can be detected by simple screening
9. MRI screenings may be better to identify breast cancer
10. Oral cancer screenings to reduce the mortality rates
11. Appendectomy need reduced with CT screening
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... ... ... A stressful work environment can hurt the physical and emotional health of employees. ... workplace. The goal of Clearview Resolution Services has always been to help others, starting ... will be shutting down the office early on Fridays. The Clearview team will use ...
(Date:4/25/2017)... ... April 25, 2017 , ... A recent report ... score performance for the 2015-16 school year across Wisconsin’s public schools, charter schools, ... highlights important patterns in student test score performance, the report’s limited analyses fail ...
(Date:4/25/2017)... ... April 25, 2017 , ... Lake Park Dental is now accepting new ... in Lutz, FL. With the help of this highly-effective, yet convenient system, patients ... complications, more discretion and less pain. , Drs. Sarah Jockin, Nicole Morganti, Sara ...
(Date:4/25/2017)... , ... April 25, 2017 , ... ... they rely on contracted partners to help with process innovation in drug formulation ... drug formulation experience along with state-of-the-art analytical equipment in support of their development ...
(Date:4/25/2017)... GA (PRWEB) , ... April 25, 2017 , ... ... their neck and back pain with a reputable physician in their area, announces the ... CRM protects patient information for patients who are looking for reputable physicians to help ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  Sorrento Therapeutics, ... antibody-centric, clinical-stage biopharmaceutical company developing new treatments for ... the closing of its previously announced underwritten public ... at a public offering price of $2.00 per ... estimated offering expenses payable by Sorrento.  The net ...
(Date:4/18/2017)... , April 18, 2017  Cardinal Health (NYSE: ... 1 fiscal 2017 earnings per share (EPS) guidance ... 2019.  This is in conjunction with this morning,s announcement ... Vein Thrombosis and Nutritional Insufficiency businesses. Cardinal ... continuing operations will be at the bottom of its ...
(Date:4/18/2017)... BLOOMINGTON, Minn. , April 18, 2017 ... ) ("Imprimis"), an ophthalmology-focused pharmaceutical company, and Cameron ... announced the signing of a three-year exclusive sales ... deploy a dedicated sales team to introduce Imprimis, ... primarily focused in 13 states in the U.S. ...
Breaking Medicine Technology: