Navigation Links
Gene Behind Lincoln’s Diseas

Nerve cells possess a protein that keeps nerve fibers flexible and a gene is responsible for the synthesis of this special type of protein, according to a study//.

A University of Utah study found that when the gene was disabled in tiny nematode worms, their nerve cells literally broke.

The discovery may provide a new explanation for spinocerebellar ataxia type 5 (SCA5), a disease previously tied to a human version of the gene and identified in 11 generations of U.S. President Abraham Lincoln's family, starting with his paternal grandparents. SCA5 may have afflicted Lincoln himself. The new study suggests how.

"Were Lincoln's nerves shattered? We don't know. But our study raises the possibility that they were," says biology Professor Michael Bastiani, the study's senior author and a member of the Brain Institute at the University of Utah.

The study involved a worm gene named unc-70 that makes a protein named beta spectrin. Humans have four beta spectrin genes, and mutations in one of them was identified previously as the cause of SCA5, a neurodegenerative disease that develops between ages 10 and 68; destroys nerve cells in the part of the brain that controls movements; causes loss of coordination in walking, speaking, writing and swallowing; and puts some patients in wheelchairs.

Earlier research showed beta spectrin makes red blood cells flexible so they don't burst, and that people with a beta spectrin mutation suffer a form of anemia.

The Utah biologists showed in nematode worms, frequently used as genetic stand-ins for humans, that loss of beta spectrin leaves neurons (nerve cells) prone to breakage. They found the microscopic protein acts like a tiny Slinky spring toy within the coating of nerve cells, giving them strength.

When 1-millimeter-long nematode worms were bred with the mutant gene, they lacked beta spectrin, resulting in breakage of their nerve cells' axons, the l
'"/>




Page: 1 2 3

Related medicine news :

1. The Logic Behind The Spread Of SARS
2. Understanding The Mystery Behind Sleepless Nights
3. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
4. Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss
5. Molecule Behind Multiple Sclerosis Discovered
6. Annual Dental Checkups in Children Lagging Behind
7. Mystery Behind The Déjà Vu Phenomenon Yet To Be Resolvd
8. NHS Says Government Advice Behind Refusal of Cancer Drug
9. Know The Brain Behind The Human Growth Hormone!
10. Vital Facts of Short Term Diets - Catch The Vitamin Behind An Ample Waist!
11. The Secret Behind Extension of Earthly Life
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene Behind Lincoln Diseas

(Date:9/2/2015)... ... September 02, 2015 , ... The 2015 ... day international investment and business conference will be hosted at five star Beijing ... The full-weekend networking conference will feature leading EB-5 industry professionals and Chinese private ...
(Date:9/2/2015)... ... September 02, 2015 , ... SonicSurg Innovations, ... market, announced today that more than 600 successful patient procedures have been performed ... Plus, nearly 70 of these procedures have been on triggering thumbs. , ...
(Date:9/2/2015)... ... ... On September 9, 2015, over 27,000 people from all over the world ... date for the state of Utah. , “We are thrilled with the overwhelming response ... doTERRA CEO. “One of the most exciting elements of our convention is the opportunity ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... ... PAYROLL FITNESS" and will provide two days of payroll education covering legislative updates, ... technology changes. The speakers, which include representatives from Ceridian, Ultimate Software, the American ...
(Date:9/2/2015)... ... ... Dr. Robert G. Schwartz , the principal of Piedmont Physical Medicine ... martial art system that is also a philosophy of life that focuses on reducing ... to the 10th century, is a Russian Martial Art that has four key principles ...
Breaking Medicine News(10 mins):Health News:The 2015 China Overseas Investment and Entrepreneurship Summit (COIES) Announced 2Health News:Trigger Tome Surpasses 600 Successful Patient Procedures 2Health News:doTERRA to Host the Largest Single-Company Convention in the State of Utah 2Health News:23rd Annual NJ Statewide Payroll Conference in Vernon, NJ at the Minerals Hotel on October 15-16, 2015 2Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 2Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 3
... Today, Tuesday, January 27, 2009, 9:30 A.M.** Elected ... Community Based Health System for Embracing Courageous New Direction ... Accord Includes Free and Fair Union ... Conference to announce historic hospital accords. WHEN: Today, ...
... seize billions from state, construct prison health care centers ... lawsuit was filed this week to prevent a federal ... dollars from California,s treasury for the sole purpose of ... Safe Ventura County opposes the proposal to construct seven ...
... Fitness Industry Leader Champions Gupta,s Commitment to Enriching Quality ... 27 The American Council on Exercise (ACE), America,s ... fitness certification, education and training organizations in the world, ... Dr. Sanjay Gupta , chief medical correspondent for the ...
... (NYSE: SGP ) today reported that it ... study, a pivotal Phase III study in treatment-naive patients. ... III study in patients who failed prior treatment that ... enrolled its registration studies for boceprevir, its lead investigational ...
... (NYSE Alternext US: ILI) today announced that the Company has ... "Exchange") that outlines the Company,s strategy to regain compliance with ... Exchange to formally respond to the submitted plan within 45 ... able to continue its listing up to June 23, 2010 ...
... ANTHEM, Ariz., Jan. 27 Prime Companies, Inc. ... , The Company has begun receiving income ... , The web site is now accessible ... , , "These are major achievements and ...
Cached Medicine News:Health News:Caritas Christi, 1199SEIU, Area Trades Council to Announce Historic New Accord to Improve Health Care for Community, Patients, Health Workers 2Health News:Caritas Christi, 1199SEIU, Area Trades Council to Announce Historic New Accord to Improve Health Care for Community, Patients, Health Workers 3Health News:Caritas Christi, 1199SEIU, Area Trades Council to Announce Historic New Accord to Improve Health Care for Community, Patients, Health Workers 4Health News:Caritas Christi, 1199SEIU, Area Trades Council to Announce Historic New Accord to Improve Health Care for Community, Patients, Health Workers 5Health News:Caritas Christi, 1199SEIU, Area Trades Council to Announce Historic New Accord to Improve Health Care for Community, Patients, Health Workers 6Health News:Ventura County Taxpayers' Group Files Suit to Stop State-of-the-Art Hospitals for Incarcerated Felons 2Health News:American Council on Exercise (ACE) Endorses Appointment of Dr. Sanjay Gupta as Surgeon General of the United States 2Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 2Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 3Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 4Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 5Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 6Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 7Health News:Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients 8Health News:Interleukin Genetics' Submits Plan to Regain Compliance with Continued Listing Standards 2Health News:Prime Companies Revenue Stream Begins; Dentists in Every City and Town Available on Company's New Web Site 2
(Date:9/2/2015)... -- Research and Markets ( ... "Pharmaceutical Regulatory Affairs in the Middle East, ... conference to their offering. An Essential ... Particularly relevant for Pharmacovigilance, Regulatory Affairs, Clinical ... Regulatory Authorities Topics to be covered ...
(Date:9/2/2015)... The acute coronary syndrome (ACS) therapeutics market consists of ... While generic ACS drugs currently lead in market revenues, ... to more than 60 percent of the total market ... products between 2015 and 2019. The US market for ... driven primarily by incidence rates of ACS and the ...
(Date:9/1/2015)... Sept. 1, 2015 On August 31, 2015, ... , issued a 123-page order in the first of ... Conserve metal-on-metal hip replacement devices are defective.[1]  ... as to Plaintiff Robyn Christiansen,s claims for defective design, ... flatly rejected Wright Medical,s claim that the Medical Device ...
Breaking Medicine Technology:Pharmaceutical Regulatory Affairs Course in the Middle East, Dubai (Dubai, UAE - October 18-19, 2015) 2Branded Acute Coronary Syndrome Therapies to Grab Market Share from Generic Drugs Globally 2Branded Acute Coronary Syndrome Therapies to Grab Market Share from Generic Drugs Globally 3Pope McGlamry: Omnibus order in Conserve Hips MDL-2329 sets stage for bellwether trial 2Pope McGlamry: Omnibus order in Conserve Hips MDL-2329 sets stage for bellwether trial 3
... Calif., Oct. 12, 2011 Ultra Clean Holdings, Inc. (Nasdaq: ... critical subsystems for the semiconductor capital equipment, flat panel, medical, ... third quarter  2011 on Monday, October 24, 2011 after markets ... to discuss third quarter 2011 results and management,s outlook at ...
... LA JOLLA, Calif., Oct. 12, 2011 A ground-breaking ... McEvoy, for the Alzheimer,s Disease Neuroimaging Initiative, 2011, Predicting ... Neurology, epub ahead of print) compared the ability of ... dementia: i) degree of memory impairment,  ii) degree of ...
Cached Medicine Technology:NeuroQuant®, CorTechs Labs' FDA-Cleared System for Quantifying Regional Brain Atrophy from MRIs, Used to Identify Patients at Highest Risk for Developing Dementia 2
Expressions lets you change your eye color with lenses that offer incredible comfort and outstanding vision quality. Expression color lenses use a technologically advanced tinting process to produce ...
Modern, innovative and quick Intense Pulsed Light system. The Flash 1 is light and very compact, thus easily portable. Available in two different colors....
... for the physician who wishes to offer ... of clinical applications. The innovative cooled Nd:YAG ... treaent of deeper lying veins. The IPL ... and pigmented lesions, including IPL Skin Treaents ...
Available in Purple, orange, dark blue, yellow, gray, royal blue, green and light blue colors....
Medicine Products: