Navigation Links
Gel Made of Patients Own Platelets may Speed Up Wound Healing

A preliminary study has suggested that topical application of a gel made from platelets in healthy individuals own blood may help wounds heal more quickly and completely .

Recent innovations have led to devices that can process blood into a concentrated plasma rich in platelets (particles important for blood clotting), and then to an autologous (from the patients own body) platelet gel, according to background information in the article. This gel is currently used in surgery to improve healing, but its clinical application remains controversial.

David B. Hom, M.D., then of the University of Minnesota School of Medicine and Hennepin County Medical Center, Minneapolis, and now at the University of Cincinnati College of Medicine, and colleagues assessed the effectiveness of autologous platelet gel in eight healthy men and women older than 21 years. Five 4-millimeter skin punch wounds were made 3 centimeters apart on both the right and left upper thighs in all eight individuals.

The autologous platelet gel was applied to the wounds on one leg, while the wounds on the other leg were treated with only an antibiotic ointment or a dressing. The wounds were monitored by the researchers and were digitally photographed for six months, and additional biopsies (removal of skin) were performed on each leg.

During the six-month follow-up, none of the participants developed infections and no serious adverse events were reported. "Over a 42-day period, the autologous platelet geltreated sites had statistically increased wound closure compared with controls by visual clinical assessment and by digital planimetry [boundary-tracing] photographic measurements," the authors write.

"On day 17, the percentage of closure was 81.1 percent for the autologous platelet geltreated sites and 57.2 percent for the control sites," they added.

Examination of biopsy specimens revealed that the histologic features of th e skin (such as cellular characteristics and microscopic signs of healing) at the treated wound sites looked similar to the skin at the control wounds. However, when the count of platelets in the gel was more than six times the count of platelets in the individuals blood vessels, new tissue appeared three days earlier in the treated wounds than in the control wounds.

"In this pilot study, autologous platelet gel appeared to enhance wound closure in acute full-thickness dermal wounds in healthy subjects," the authors conclude.

"Further investigations are needed to confirm the consistency of these results. If further studies support these findings, autologous platelet gel treatment during surgery could have a useful impact on the enhancement of postoperative dermal wound healing in surgical patients, the authors added.

The study is published in the in the May/June issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.


'"/>




Related medicine news :

1. One in Three Heart Attack Patients Have No Chest Pains
2. Amphetamines Help Recovery of Stroke Patients
3. Painkillers Do Not Shorten Dying Patients Lives
4. Patients With Filariasis More Prone To HIV Infection
5. Glivec - New Hope For CMC Patients
6. Patients often assume wrongly that they are allergic to penicillin
7. New FDA Approved Drug NATRECOR For Heart Failure Patients
8. Hemochromatosis Patients Blood is Safe
9. Patients Pressure Would Result In Overprescription
10. Risk Of Decongestants In Hypertensive Patients
11. Interference helps Heart Patients
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... Maryland (PRWEB) , ... June 24, 2016 , ... ... Angels is actively feeding the Frederick area economy by obtaining investment capital for ... over the past 2½ years that have already resulted in more than a ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- One of Australia,s successful biotechnology scientists, ... new biotechnology company, Noxopharm Limited [ABN 50 608 966 123] ("Noxopharm"). ... list on the ASX. Noxopharm is a clinic-ready company ... Phase 1 clinical study later this year. ... biggest problems facing cancer patients - the ability of cancers to ...
(Date:6/26/2016)... June 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as ... Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) ... Daylight Time). As previously announced on May ... definitive merger agreement under which Jazz Pharmaceuticals has commenced ...
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
Breaking Medicine Technology: