( ion and weight will be monitored and bl...)Garlic Hope in Infection Fight,Health

ion and weight will be monitored and blood tests carried out to ensure the garlic capsules are safe.

Dr Alan Smyth of the University's School of Human Development, who is leading the project, said: “The garlic components inhibit a bacterial communication system called quorum sensing (QS). This is responsible for the germ forming tenacious colonies in the lungs called 'biofilms'. The QS molecules also switch on bacterial weapons such as 'elastase', an enzyme that breaks down elastic tissue in the lung.

“The beauty of this approach is that we may be able to render the germ harmless without killing it. If we use a conventional antibiotic, which kills the Pseudomonas, there will always be some survivors, some of which may develop antibiotic resistance. The trick is not to allow Pseudomonas to use natural selection as a weapon against us.”

The Nottingham University Hospitals NHS Trust and The University of Nottingham funded the study; with garlic capsules supplied by the Nottingham-based company Boots.

Among Dr Smyth's collaborators on the project at The University of Nottingham are Dr David Barrett in the School of Pharmacy, Dr Alan Knox in the School of Medical and Surgical Sciences and Professor Paul Williams, Dr Miguel Camara and Dr Karima Righetti — an EU-funded Marie Curie fellow — in the School of Molecular Medical Sciences.

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