Navigation Links
Fungal toxins infected corn the reason for congenital defects

Fungal toxins in corn may be the reason for neural tube defects outbreak in the Rio Grande Valley during the early 1990's.

The study published in the on line journal Environmental Health Perspectives suggests that corn and its products //that have been infected by fungal toxins might give rise to neural tube defects (NTD), if consumed during the first trimester of pregnancy.

Talking about “Neural tube defects” these are embryonic defects of the brain and spinal cord resulting from failure of the neural tube to close.

The aim of the study was to investigate whether tortillas contaminated with fumonisin caused the neural tube defects outbreak (1990-1991) in Cameron County, Texas.

The human outbreak of neural tube defects occurred during the same crop year as epizootics, attributed to exposure to fumonisin, a mycotoxin produced by the molds Fusarium verticillioides that often contaminates corn, according to the article.

The type of the study was population-based case control study, in which the researchers estimated the exposure to fumonisins during the first trimester from a postpartum sphinganine:shingosine ratio (sa:so ratio), a marker for fumonisin exposure measured in maternal serum, and corn tortilla intake based on the maternal recall.

225 Mexican-American women with NTD-affected pregnancies and 378 Mexican-American women with healthy births were the study group. Among them, 184 NTD-affected women and 225 control women participated in an interview. Among the interviewed, 163 case women and 189 control women provided blood samples for the sa:so ratio test.

The results based on the study was that those who consumed 301 to 400 tortillas during the first trimester were more than twice likely to have NTD-affected pregnancies compared to those who consumed 100 or less. Additionally, 401-800 tortillas during the first trimester were associated with a slightly decreased risk o f NTD.

Based on the postpartum sa:so ratio, increased exposure to fumonisins was associated with an increased risk of NTD.

The results of the study suggest the risk of neural tube defects increases as exposure to fumonisins increases to a threshold, at which fetal death can be caused.

Stacey A. Missmer and colleagues at Harvard School of Public Health, Boston, MA, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, Texas Department of State Health Services, Austin, TX, and Boston University School of Public Health, Boston, MA, and the Medical Institute, Austin, TX were the researchers who took upon themselves the mantle if the study and proved a thought hypothesis. They established the link between corn consumption and NTD outbreak linking it to fungi toxins.


Related medicine news :

1. Cure For Persistent Oral Fungal Problem May Be Possible
2. Fungal Infections Effectively Controlled By Light Therapy
3. Fungal spores in the pillows can trigger an asthma attack
4. Immunosuppressive Action Of Fungal Metabolite - Gliotoxin
5. Contact Lenses Implicated in Fungal Infections
6. Spread Of Fungal Infections At Gym Could Be Avoided By Using Towel
7. Lens Wearers Alerted Over Dangerous Fungal Infection
8. Reports Characterize Fungal Eye Infections Among Soft Contact Lens Wearers
9. Noxafil Can Help Invasive Fungal Infections
10. Noxafil Drug Better in Fighting Deadly Fungal Infections
11. Risk Of Asthma Rises Due to Endotoxins
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud to ... Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored ... one of twelve colleges and universities in the state of California make the cut. ...
(Date:11/26/2015)... ... November 26, 2015 , ... Patients ... central Michigan, have come together on Thanksgiving Day to share the things that ... viewing on the Serenity Point YouTube channel, patients displayed what they wrote on ...
(Date:11/26/2015)... ... ... Jobs in hospital medical laboratories and in the imaging field lead the ... Aureus Medical Group . These fields, as well as travel nursing, ranked ... jobs through the company’s website, , The leading healthcare staffing agency ...
(Date:11/26/2015)... ... ... Indosoft Inc., developer and distributor of the world-class Asterisk based contact center ... reliability. , The new Q-Suite 6 platform is based on the latest Java Enterprise ... a specific piece of software for many key components of the suite. Much of ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... recognized once again for its stellar workplace culture with the company’s Cincinnati office ... , Medical Solutions’ Cincinnati office was named a finalist in Cincinnati Business Courier’s ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... "Self Administration of High Viscosity Drugs" report ... has announced the addition of the "Self ... their offering. --> Research and Markets ... the "Self Administration of High Viscosity Drugs" ...
(Date:11/26/2015)... November 26, 2015 ... the "Radioimmunoassay Market by Type (Reagents ... Industry, Academics, Clinical Diagnostic Labs), Application (Research, ... to 2020" report to their offering. ... the addition of the "Radioimmunoassay Market ...
(Date:11/25/2015)... 25, 2015 ... the "Global Brain Monitoring Devices Market ... --> ) has announced the ... Devices Market 2015-2019" report to their ... ( ) has announced the addition ...
Breaking Medicine Technology: