Navigation Links
Fresh approach to TB treatment

A NOVEL approach to the treatment of tuberculosis (TB) has been investigated by a team of molecular geneticists in the United Kingdom, following the direction of a new gene in mycobacteria, one type of which causes the disease.//The presence of the gene opens up opportunities for the use of azole drugs which are already available for ht etreatment of fungal infections.

These treatments such as in Canestan and Diflucan are central to antifungal treatments of patinets suffering infections such as Canadida albicans but also increasingly in internal fungal infections.New azole drugs are being developed against fungi as the incidence of infection has increased dramatically in recent years.The potential value of these drugs against mycobacteria had not received attention because were not thought to contain this drug target which is associated with the sterol bio-synthesis pathway.

Laboratory tests have already shown that some of these drugs work on various mycobacteria, including the BCG strain that is used for inoculations and Mycobacterium Smegmatis, generally an opportunistic pathogen.The equivalent of the target of the drugs in fungi has been detected in several mycobacterial pathogens including that causing TB and the protein in the BCG strain is identical to that in M. Tuberculosis causing TB.

These results suggest that the drugs are also likely ot be active against the strains that cause infection.Further tests will confirm which of the family of azole drugs could be candidates for fast-tracking the drug discovery programme.Professor Steven Kelley, of the Institute of Biological Sciences at University of Wales Aberystwyth, said:“The sterol biosynthesis pathways are commonly found in fungi, animals and plants but this was the first that this gene had been found in bacteria. We now see the gene in several of the databases containing the genetic blueprints of different mycobacteria.

“It gives us the prospect of using exis
'"/>




Page: 1 2

Related medicine news :

1. Fresh warnings to doctors regarding abortion pill
2. Fresh Cases of Bird-Flu Prepares the Ground for More Chicken Martyrs
3. Fresh Bird Flu Cases Spotted In Southern Russia
4. Pakistan Scared By Fresh Bird Flu Case
5. Fresh Polio Cases Reported In Uttar Pradesh
6. Nothing Can Equate Fresh Vegetables and Fruits
7. Fresh Outbreak Of Bird Flu In Nigeria
8. Foreign Fresher Students Offered Scholarship By Fudan
9. Fresh bird flu vaccines made in China
10. Freshness Dating? Researchers Express Doubts
11. WHO Issues Fresh Guidelines To Long Distance Air Travelers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fresh approach treatment

(Date:12/21/2014)... (PRWEB) December 21, 2014 The number ... in a consolidated litigation underway in New Jersey, Bernstein ... total of 1,375 claims involving the birth control IUD ... These lawsuits were filed by women who allege spontaneous ... led to uterine perforations and other complications they were ...
(Date:12/21/2014)... (PRWEB) December 21, 2014 SCI ... of the issues and systemic barriers for disabled athletes ... Paratriathlon Champion. Scheidies has a condition called juvenile macular ... He describes how he adapted his athletic ambitions to ... his success in triathlon to pioneer the way for ...
(Date:12/21/2014)... Concept Plus, LLC. a SDB and 8(a) certified ... today announced it has been recognized by Washington Technology ... the fastest growing government contracting small businesses by calculating their ... is the first year that Concept Plus, LLC., participated in ... 95.92% compound annual growth rate. “For Concept Plus to be ...
(Date:12/20/2014)... York, NY (PRWEB) December 20, 2014 ... the healthcare sector have benefited the Massage Services ... the discretionary characteristics of industry products, the anticipated 1.0% ... five-year period has provided consumers with the means to ... that have received a massage in a given year ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress wholesaler and retailer, ... for 2015. Great discounts are now offered on all ... get a discount, up to 80% off, when they ... 30, 2015. , VogueQueen.com has recently released its new ... promotion. Many customers worldwide like VogueQueen’s special designs which ...
Breaking Medicine News(10 mins):Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2
... ... ... ... ...
... BUFFALO, N.Y. -- Hypnosis can help alleviate the pain and ... to a study by a University at Buffalo School of ... suffering, frequency of pain and degree of constant pain among ... Butler, associate professor in UB,s School of Social Work, a ...
... Drug already approved for arthritis looks promising in lab ... -- Most pancreatic cancer patients die soon after diagnosis, ... be a promising new treatment target. , Even more ... already approved to treat rheumatoid arthritis and are undergoing ...
... years ago, researchers say, , FRIDAY, Feb. 26 (HealthDay News) ... more than 12,000 years ago, new research suggests. , The ... is a major determinant of small size in dogs. The ... of the Middle Eastern gray wolf, according to the study, ...
... , ... ... ... ...
... , ... ... , , , ... ...
Cached Medicine News:Health News:High Representative Ashton and Commissioner Georgieva to Visit Haiti 2Health News:High Representative Ashton and Commissioner Georgieva to Visit Haiti 3Health News:High Representative Ashton and Commissioner Georgieva to Visit Haiti 4Health News:Hypnosis can help control pain among women with metastatic breast cancer, UB Researcher finds 2Health News:New Treatment Eyed for Deadly Pancreatic Cancer 2Health News:New Treatment Eyed for Deadly Pancreatic Cancer 3Health News:Hope Phones, IntraHealth and FrontlineSMS:Medic Collaborate on Phone Donation Campaign to Support Health Workers in Africa 2Health News:Hope Phones, IntraHealth and FrontlineSMS:Medic Collaborate on Phone Donation Campaign to Support Health Workers in Africa 3Health News:Hope Phones, IntraHealth and FrontlineSMS:Medic Collaborate on Phone Donation Campaign to Support Health Workers in Africa 4Health News:Hope Phones, IntraHealth and FrontlineSMS:Medic Collaborate on Phone Donation Campaign to Support Health Workers in Africa 5Health News:Brain Cancer Survivor Will Cycle 4,170 Miles Across USA to 'Outsmart' Disease 2Health News:Brain Cancer Survivor Will Cycle 4,170 Miles Across USA to 'Outsmart' Disease 3Health News:Brain Cancer Survivor Will Cycle 4,170 Miles Across USA to 'Outsmart' Disease 4
(Date:12/17/2014)... , Dec. 17, 2014  Northstar Global Business ... Trust Company (DTC) has made their final decision ... on the Company,s stock effective December 15, 2014, ... stock for depository and book entry transfer services. All ... is now once again fully "DTC Eligible", and ...
(Date:12/17/2014)... LOS ANGELES , Dec. 17, 2014 /PRNewswire/ ... that the US Patent and Trademark Office (USPTO) ... candidate ICT-107, a dendritic cell-based immunotherapeutic vaccine targeting ... glioblastoma. The claims of US Patent No. 8,871,211, ... treating neural cancer by administering a dendritic cell ...
(Date:12/17/2014)... , Dec. 17, 2014 PCCA ... Approved ( http://bit.ly/1382OkS ) program seal for ... community. The program highlights medical practices, materials and ... "autism-community friendly." Children affected by autism ... can be exacerbated by ingredients found in food ...
Breaking Medicine Technology:Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: