Navigation Links
Fragile X-Associated Tremor /Ataxia Syndrome Need Guidelines For Diagnostic Tests

Fragile X-associated tremor /ataxia syndrome (FXTAS) needs guidelines to have diagnostic// tests designed for early detection, as it is difficult to diagnose.

According to a study published in the July 26 issue of Neurology, the scientific journal of the American Academy of Neurology, diagnosis of the disease early is required as the disease is often confused with other similar disorders.

A multi-center study found 56 people had received 98 prior diagnoses, including Parkinson?s and essential tremor, before FXTAS was concluded. The researchers believe this was partly due to the recent definition of FXTAS and a lack of familiarity with the disorder. The information about previous diagnoses encouraged them to develop guidelines for diagnostic testing for FXTAS.

Men age 50 and older who develop unexplained ataxia should undergo testing to check if they have the FMR1 gene, said co-author Maureen A. Leehey, MD, of the University of Colorado Health Sciences Center in Denver. ?Also men 50 and older who have tremor, Parkinson?s disease, or dementia, along with a family history of developmental delay, autism, mental retardation, or premature ovarian failure, should be tested for the gene.

These guidelines are reasonable but may change in the future as larger numbers of patients are detected, according to an editorial published in the same issue of Neurology.

A second study in Ireland examined a 70-year-old woman with mild ataxia and tremor that became severe after receiving chemotherapy to treat breast cancer. She had two sons with Fragile X syndrome. The researchers concluded she had FXTAS after a genetic test using DNA from a blood sample showed that she carried the FMR1 gene. Her symptoms became mild again after chemotherapy stopped.

About 1 in 259 women carry the FMR1 gene, but FXTAS is rarely reported in women, said co-author John P. O?Dwyer, MRCPI, of St. Vincent?s University Hospital in Dublin.

You might expect to see FXTAS more often, but it may only become evident when toxic effects from a procedure like chemotherapy push mild symptoms to the forefront.

Source: Newswise

Medindia on FXTAS : Further information

Fragile X-associated tremor /ataxia syndrome or FXTAS: This is a neurological disorder that affects men in the age of 50 yrs or more and causes tremor, problems in the balance and dementia and the condition becomes stronger with age. Often the disease is confused with Parkinson's disease or Alzheimer's disease. The cause of the disorder is a mutation of the fragile X gene that causes mental retardation.

'"/>




Related medicine news :

1. Babies Brains Are more Fragile
2. Tremors connected to Body Mass Index
3. Botox Found To Be Effective for Voice Tremors
4. Early Clue to Down Syndrome
5. Hope For Stiff-Person Syndrome
6. Restless Legs Syndrome - Help at hand
7. Severe Acute respiratory Syndrome (SARS)
8. WHO Travel Advice to prevent spread of "Severe Acute Respiratory Syndrome (SARS)
9. Treatment for Syndrome X
10. “ Economy Class Syndrome
11. Dementia and Down Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... TopConsumerReviews.com ... by Native Remedies that helps promote pancreatic health and regulate blood sugar ... some prescription-based approaches can have negative side effects, and with the changes in ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... “Letters From ... all people, even the lost, have value to God. “Letters From Home” is the ... and a member of the President’s Cabinet of Jerry Savelle Ministries International, who has ...
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... 38-Year-Old Plastic ... Surgery Center in Naples, Florida is pleased to announce that Plastic Surgeon Kiranjeet Gill ... 40 Under 40 is an annual award that was started in 2003 ...
(Date:9/21/2017)... ... 2017 , ... Hair restoration surgery is having a moment, ... International Society of Hair Restoration Surgery (ISHRS). The worldwide volume of ... 635,189 procedures performed in 2016. , "Like other forms of cosmetic surgery ...
(Date:9/21/2017)... ... ... The New England Center for Children® (NECC®), a global leader in education ... the Board of Directors. , “The New England Center for Children is honored ... addition to our team,” said Vincent Strully, Jr., President and CEO of The New ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... YORK , Sept. 8, 2017 Dealmed ... largest independent supplier of medical equipment, supplies, drugs, vaccines, ... it has entered into an agreement to acquire Vantage ... equipment based in Holtsville, New York ... specializes in supplying new and emerging medical practices, will ...
(Date:9/7/2017)... Caris Life Sciences, a leading innovator ... of precision medicine, today announced results from two ... molecular profiling approach in guiding therapeutic strategies in ... (CGP+) with Caris Molecular Intelligence ® to ... level, leading to more therapeutic options and improved ...
(Date:9/6/2017)... , Sept. 6, 2017  Robert G. Szewc, ... Pinnacle Professional Member in recognition of his contributions to ... serves as a Nephrologist at the practice of Kidney ... medicine, kidney care and hypertension solutions. He has worked ... years of career experience, as well as expertise in ...
Breaking Medicine Technology: