Navigation Links
Fragile X-Associated Tremor /Ataxia Syndrome Need Guidelines For Diagnostic Tests

Fragile X-associated tremor /ataxia syndrome (FXTAS) needs guidelines to have diagnostic// tests designed for early detection, as it is difficult to diagnose.

According to a study published in the July 26 issue of Neurology, the scientific journal of the American Academy of Neurology, diagnosis of the disease early is required as the disease is often confused with other similar disorders.

A multi-center study found 56 people had received 98 prior diagnoses, including Parkinson?s and essential tremor, before FXTAS was concluded. The researchers believe this was partly due to the recent definition of FXTAS and a lack of familiarity with the disorder. The information about previous diagnoses encouraged them to develop guidelines for diagnostic testing for FXTAS.

Men age 50 and older who develop unexplained ataxia should undergo testing to check if they have the FMR1 gene, said co-author Maureen A. Leehey, MD, of the University of Colorado Health Sciences Center in Denver. ?Also men 50 and older who have tremor, Parkinson?s disease, or dementia, along with a family history of developmental delay, autism, mental retardation, or premature ovarian failure, should be tested for the gene.

These guidelines are reasonable but may change in the future as larger numbers of patients are detected, according to an editorial published in the same issue of Neurology.

A second study in Ireland examined a 70-year-old woman with mild ataxia and tremor that became severe after receiving chemotherapy to treat breast cancer. She had two sons with Fragile X syndrome. The researchers concluded she had FXTAS after a genetic test using DNA from a blood sample showed that she carried the FMR1 gene. Her symptoms became mild again after chemotherapy stopped.

About 1 in 259 women carry the FMR1 gene, but FXTAS is rarely reported in women, said co-author John P. O?Dwyer, MRCPI, of St. Vincent?s University Hospital in Dublin.

You might expect to see FXTAS more often, but it may only become evident when toxic effects from a procedure like chemotherapy push mild symptoms to the forefront.

Source: Newswise

Medindia on FXTAS : Further information

Fragile X-associated tremor /ataxia syndrome or FXTAS: This is a neurological disorder that affects men in the age of 50 yrs or more and causes tremor, problems in the balance and dementia and the condition becomes stronger with age. Often the disease is confused with Parkinson's disease or Alzheimer's disease. The cause of the disorder is a mutation of the fragile X gene that causes mental retardation.


Related medicine news :

1. Babies Brains Are more Fragile
2. Tremors connected to Body Mass Index
3. Botox Found To Be Effective for Voice Tremors
4. Early Clue to Down Syndrome
5. Hope For Stiff-Person Syndrome
6. Restless Legs Syndrome - Help at hand
7. Severe Acute respiratory Syndrome (SARS)
8. WHO Travel Advice to prevent spread of "Severe Acute Respiratory Syndrome (SARS)
9. Treatment for Syndrome X
10. “ Economy Class Syndrome
11. Dementia and Down Syndrome
Post Your Comments:

(Date:6/26/2016)... ... 27, 2016 , ... Quality metrics are proliferating in cancer care, and are ... the eye of the beholder, according to experts who offered insights and commentary in ... Managed Care. For the full issue, click here . , For the American ...
(Date:6/26/2016)... ... 2016 , ... PawPaws brand pet supplements owned by Whole Health ... the health of felines. The formula is all-natural and is made from Chinese herbs ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Bracket , a leading ... next generation clinical outcomes platform, Bracket eCOA (SM) 6.0, ... June 26 – 30, 2016 in Philadelphia ... Clinical Outcome Assessment product of its kind to fully integrate ... Bracket eCOA 6.0 is a flexible platform for electronic ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, 2016 ... Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, the ... announced today online at by the ... diabetes stand in the way of academic and community ... Foundation,s scholarship program since 2012, and continues to advocate ...
(Date:6/23/2016)... -- Revolutionary technology includes multi-speaker listening to ... leaders in advanced audiology and hearing aid technology, has ... the world,s first internet connected hearing aid that opens ...      (Photo: ) , ... firsts,: , TwinLink™ - the first dual ...
Breaking Medicine Technology: