Navigation Links
Four-way Dengue Vaccine a 'success', Say Scientists

Researchers in the United States have developed a method that could lead to a single vaccine against all four types of the dengue// virus.

The dengue virus causes dengue hemorrhagic fever, shock and encephalitis. The four types of virus are all sufficiently different that individuals vaccinated against one virus type are still vulnerable to infection by the others.

There is currently no commercially available vaccine for protection against all types of dengue virus.

But John Dong of the Medical University of South Carolina, United States, and colleagues have developed a method that could lead to a safe and effective vaccine for all four types of the virus.

They produced a pair of synthetic vaccines, each containing genes from two of the four virus types. These successfully mimicked natural infection in mice, inducing an immune response against each of the four virus types at once.

The research was published in the February issue of the journal Clinical and Vaccine Immunology.

According to Dong, the synthetic vaccine demonstrated "100 per cent efficacy" in protecting the mice against all four dengue viruses. He added that the vaccine had also demonstrated safety in preclinical toxicology studies.

Dong told SciDev,Net that a further study on non-human primates has been conducted and will soon be submitted to a scientific journal for publication by colleagues at the US-based Naval Medical Research Center.

Prida Malasit of the Medical Biotechnology Unit in Bangkok, Thailand, welcomed the development. "There is no doubt on the importance of having the vaccine" he said.

He added that controlling dengue viruses was becoming a "formidable task for every country, not only for developing countries" because of rapidly expanding urbanisation and international travel.

Source-Bio-Bio Technology

Page: 1

Related medicine news :

1. Dengue Outbreak in Kolkata, Four Dead
2. Dengue in Delhi – 26 Cases reported and 3 dea
3. Dengue fever in Delhi after the Monsoon
4. Dengue Claims 15 Lives In West Bengal
5. Dengue Epidemic in West Bengal: Over 1000 New Cases and 15 dead
6. 45 People die in West Bengal due to Dengue and suspected Japanese Encephalitis
7. Vaccine For Dengue Fever On Trial In Asia-Pacific
8. Dengue Fever Claims Five Lives In Pakistan
9. Fear Of Dengue Epidemic Looms Large: Fever Kills Five in Pakistan
10. Delhi Launches Special Drive to Check Dengue Spread
11. MCD Takes Steps To Prevent, Control Dengue
Post Your Comments:

(Date:11/30/2015)... ... 30, 2015 , ... Until now, the St. Louis Fetal Care Institute ... of Myelomeningocele Study) trial. One of these exclusion criteria was a BMI above 34.9. ... to 24.9 is considered normal, 25 - 29.9 is overweight and above 30 is ...
(Date:11/30/2015)... ... November 30, 2015 , ... Thermi™, a world ... announce that its ThermiRFR temperature controlled radiofrequency platform has received CE marking and ... platform which uses temperature as a clinical endpoint. The technology has been ...
(Date:11/30/2015)... ... November 30, 2015 , ... The world of hair transplants and restoration is ... These techniques and procedures have been in use for many years and are among ... Parsa Mohebi, M.D. has utilized many of these methods over the years, he also ...
(Date:11/30/2015)... ... November 30, 2015 , ... The presidential race normally ... styling. So why is it a national news story when Donald Trump makes disparaging ... M.D., because appearances count more than anyone wants to admit when it comes to ...
(Date:11/30/2015)... , ... November 30, 2015 , ... According to Los ... people to overeat are not necessarily caused by real hunger, but instead by ... needs food. He notes that, while many patients are aware that weight loss surgery ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... 2015   Royal Philips  (NYSE: PHG ... Radiology Solutions, a fully integrated, consultative approach to ... data-driven practice management approaches that combine imaging systems, ... improve care delivery and reduce costs. Making its ... North America Annual Meeting (RSNA) in ...
(Date:11/30/2015)... -- global cell culture market is expected to ... by 2022 at a CAGR of 7.1% therein. --> ... 2013 value of US$6.1 bn to US$11.3 bn by 2022 at ... has announced the release of a new market research study, detailing ... Culture Market - Global Industry Analysis, Size, Share, Growth, Trends and ...
(Date:11/30/2015)... , Nov. 30, 2015   Royal Philips ... Implant, the industry,s first MRI guided user interface and ... of patients with MR Conditional implants, such as knee ... 2015 Radiological Society of North America Annual Meeting ... and supports diagnostic confidence of this growing patient population. ...
Breaking Medicine Technology: