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For Kids With High BP, Surgery Can Help When Medicines Fail

High blood pressure may seem like something that only adults get, after years of smoking, overeating and little exercise. But children can develop// it too -- and just as in adults, uncontrolled high blood pressure can pose serious risks to children’s hearts, brains and lives.

While medications may help some children with high blood pressure, surgery is the best option for those with renal artery obstructions, causing a rare but especially dangerous form of hypertension. That’s the conclusion of a new study published in the Journal of Vascular Surgery by a University of Michigan Cardiovascular Center team that is among the world’s most experienced at treating such children.

Called pediatric renovascular hypertension, the disease is caused by narrowings, or stenoses, in the blood vessels that lead to the kidneys.

It’s often diagnosed only after children don’t respond to blood pressure medications, or after they experience symptoms such as failing to gain weight at a normal pace or having unexplained fatigue. For some kids, the diagnosis comes only after a stroke.

The condition, which is the third most common cause of serious hypertension in children, often develops as a result of developmental narrowings in the renal arteries, the name for vessels that bring blood to the kidneys. In some children, the nearby section of the aorta — the largest blood vessel in the body — also has narrowings. Children who have a genetic disease called neurofibromatosis are especially at risk.

The kidneys play a major role in regulating blood pressure, by filtering waste from the blood and releasing hormones. But if the blood vessels that feed them become narrowed or partially blocked, the kidneys retain fluids and send out a hormone called renin that causes blood vessels throughout the body to constrict, thereby increasing blood pressure. Fortunately, the new study shows that 97 percent of children who have surgery for renovascular hyp
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