Navigation Links
Focused Treatment For Childhood Cancer

A poorly understood type of childhood brain cancer has a unique molecule signature that may point to which therapies could best fight it.// Armed with targeted molecular treatments, doctors may be able to fight the disease without risking the side effects of prolonged and powerful radiation and chemotherapy at an early age.

The latest research is a collaborative effort looking at a type of childhood tumour known as medulloblastoma, the most common childhood tumour of the CNS. The cancer usually strikes between the ages of 5 and 10. Medulloblastomas are highly malignant, and can spread to the spine and other parts of the body. But over the past few decades, refined treatments have increased survival rates until approximately 80 percent of children survive for five to 10 years after diagnosis.

But the therapies aren't perfect. Radiation and chemotherapy for up to a year at such a young age can lead to hearing loss, cataracts and severe learning disabilities that can leave children unable to live independently in later life.

Led by Dr. Scott Pomeroy, an associate professor of neurology at Children's Hospital in Boston, the researchers found that increased activity of Sonic Hedgehog (SHH), a signaling molecule crucial to brain development, is linked to one type of medulloblastoma. "As compared to chemotherapy, which is non-specific and damages all cells … these very focused treatments will only work on those tumors that have that particular molecular pathway active," says Pomeroy.

Recently developed compounds that can block the uncontrolled SHH signaling found in the tumors could potentially be used as a therapy in children with medulloblastoma. Researchers also found that the clinical outcome of an individual child's struggle with medulloblastoma could be accurately predicted by examining the patterns of gene expression in the cancer at the time of diagnosis.
'"/>




Page: 1

Related medicine news :

1. Advances in Treatment of Cataracts
2. Recommendations for Treatment of Blood Pressue
3. Treatment for Menieres disease
4. Treatment for pre-menstrual syndrome is ineffective
5. Better Treatment for obesity
6. Gene Treatment for Heart Disease
7. More People Seeking Treatment for Depression
8. Inadequate Drug Treatment For Youth
9. FDA Approves New surgery Treatment for Farsightedness
10. Treatment of antibiotics ineffectual in bronchitis
11. Oxygen Treatment may be injurious
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... ... April 25, 2017 , ... ... and HR decision-makers are preparing for how his administration could impact the employee ... insight into what changes are most likely to make it through Congress. His ...
(Date:4/25/2017)... Las Vegas, NV (PRWEB) , ... April 25, ... ... teeth can now choose a modern procedure that achieves results in a fraction ... orthodontist in Las Vegas, NV, with Significance Dental Specialists, now offers this ...
(Date:4/25/2017)... ... April 25, 2017 , ... Buyers and sellers in the ... dispensaries and head shops –can’t help but be heartened by the industry’s current surge. ... odor aptly described as “skunk smell.” At last they can simply, safely and ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... There is ... Regional Hospital, according to a special report in the May issue of Consumer Reports ... its highest quality ranking for results achieved during and after coronary bypass and aortic ...
(Date:4/24/2017)... ... 2017 , ... LG CNS Healthcare Solutions debuted the next ... Telehealth 2.0, the American Telemedicine Association’s national conference. , BYOD has been added ... pre-programmed tablet in a remarkably easy-to-use kit for patients. “BYOD is the next ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Research and Markets has announced the addition of the ... Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2014 ... ... US$ 7,167.6 Mn in 2015, and is expected to reach ... 5.6% from 2016 to 2024. The global ...
(Date:4/19/2017)... April 19, 2017 /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) ... & Co. Healthcare Investor Conference 2017 at the Sheraton Hotel in ... , Chief Executive Officer of the Company is scheduled to present ... Richard Bear and the Chairman of the Board, Tony ... ...
(Date:4/19/2017)... NEW YORK , April 19, 2017 ... Surgical drainage devices are tubes used to remove excess ... include, blood, serum, pus, urine, bile or lymph. Surgical ... types of surgery such as orthopedics surgery, cardiovascular surgery, ... device is prophylactic post-surgery to prevent accumulation of fluid ...
Breaking Medicine Technology: