Navigation Links
Focused Treatment For Childhood Cancer

A poorly understood type of childhood brain cancer has a unique molecule signature that may point to which therapies could best fight it.// Armed with targeted molecular treatments, doctors may be able to fight the disease without risking the side effects of prolonged and powerful radiation and chemotherapy at an early age.

The latest research is a collaborative effort looking at a type of childhood tumour known as medulloblastoma, the most common childhood tumour of the CNS. The cancer usually strikes between the ages of 5 and 10. Medulloblastomas are highly malignant, and can spread to the spine and other parts of the body. But over the past few decades, refined treatments have increased survival rates until approximately 80 percent of children survive for five to 10 years after diagnosis.

But the therapies aren't perfect. Radiation and chemotherapy for up to a year at such a young age can lead to hearing loss, cataracts and severe learning disabilities that can leave children unable to live independently in later life.

Led by Dr. Scott Pomeroy, an associate professor of neurology at Children's Hospital in Boston, the researchers found that increased activity of Sonic Hedgehog (SHH), a signaling molecule crucial to brain development, is linked to one type of medulloblastoma. "As compared to chemotherapy, which is non-specific and damages all cells … these very focused treatments will only work on those tumors that have that particular molecular pathway active," says Pomeroy.

Recently developed compounds that can block the uncontrolled SHH signaling found in the tumors could potentially be used as a therapy in children with medulloblastoma. Researchers also found that the clinical outcome of an individual child's struggle with medulloblastoma could be accurately predicted by examining the patterns of gene expression in the cancer at the time of diagnosis.
'"/>




Page: 1

Related medicine news :

1. Advances in Treatment of Cataracts
2. Recommendations for Treatment of Blood Pressue
3. Treatment for Menieres disease
4. Treatment for pre-menstrual syndrome is ineffective
5. Better Treatment for obesity
6. Gene Treatment for Heart Disease
7. More People Seeking Treatment for Depression
8. Inadequate Drug Treatment For Youth
9. FDA Approves New surgery Treatment for Farsightedness
10. Treatment of antibiotics ineffectual in bronchitis
11. Oxygen Treatment may be injurious
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/16/2019)... ... 15, 2019 , ... At their 36th Annual Awards Gala on November 12th ... for programs and services benefiting Calvary patients and their families. Ryan Field, WABC-TV Sports ... The Chiffons, and Shirley Alston Reeves, original lead singer of The Shirelles. ...
(Date:11/16/2019)... ... November 15, 2019 , ... ... the United States, access to cannabis via well-managed dispensaries becomes more and more ... Business Plans, industry-leading online provider of state-of-the-art, online, custom cannabis business plans is ...
(Date:11/15/2019)... ... 2019 , ... Anxiety is sweeping the country in epidemic ... current figures of adults who suffer at 40 million, yet only 36.9% of ... different ways, including Post Traumatic Stress Disorder (PTSD), phobias, Generalized Anxiety Disorder (GAD), ...
(Date:11/15/2019)... ... November 15, 2019 , ... Spectrum Vision Partners claimed 13th ... Workplaces for 2019. The recently announced rankings honor those organizations where employees feel ... partnership with Energage to conduct surveys into organizational health and identify Long Island ...
(Date:11/14/2019)... ... November 14, 2019 , ... ... Loma Linda University International Heart Institute have performed a pioneering coronary intervention ... the axillary artery in the shoulder. The new procedure offers surgeons another option ...
Breaking Medicine News(10 mins):
(Date:11/19/2019)... (PRWEB) , ... November 19, 2019 , ... ... management of hemophilia, which aims to ensure that members receive hemophilia drugs from ... that increases costs. Beginning in January of 2020, Highmark members will receive hemophilia ...
(Date:11/19/2019)... (PRWEB) , ... November 19, 2019 , ... Dr. David ... Surgery in Los Angeles. Carla's expertise in nonsurgical and body contouring procedures is ... CoolSculpting®. , " Carla is among an exclusive group of experts in ...
(Date:11/19/2019)... (PRWEB) , ... November 18, 2019 , ... “Comprehensive Vital ... Cell-lines”” by Alan J. Balmer has been named No. 1 International Best Seller on ... No. 1 Hot New Release in Cell Biology, Nosology, and Reference. , The ...
Breaking Medicine Technology: