Navigation Links
First Gene Chip Discovered by Cincinnati Researchers

Researchers at Cincinnati Children's Hospital Medical Center have developed the first gene chip, termed as “Jaundice Chip” that may lead to early diagnosis of at// least five hereditary liver diseases. The chip may also be used to detect genetic causes of jaundice in children and adults, and potentially to lead to personalized treatment options.

The Cincinnati Children's study results were published in the January issue of the journal Gastroenterology. According to the study, the chip is nearly 100 percent effective in the detection of the most common mutations in children with inherited causes of jaundice.

"Other chips have been developed to assess drug metabolism," said Jorge Bezerra, MD, a pediatric gastroenterologist at Cincinnati Children's and the study's lead investigator. "This is the first chip in the world that has been customized to diagnose genetic mutations in patients with inherited types of liver diseases."

The chip uses a new technology that rapidly and accurately discloses the composition of several genes known to cause liver disease in children and adults. "The jaundice chip may also help us to discover whether subtle changes in these five genes that can cause devastating diseases in children may also modify the clinical course of other common liver diseases in adults,"said Mitchell Cohen, M.D., director of the division of gastroenterology hepatology and nutrition at Cincinnati Children's.

Jaundice is a yellowing of the eyes and skin caused by impairment in bile flow from the liver to the intestine. Impaired bile flow, or cholestasis, commonly known as jaundice, can lead to severe liver disease. In children, jaundice and cirrhosis are responsible for more than half of the need for liver transplantation.

Previous research on humans identified five genes responsible for inherited forms of jaundice, until now, the broad array of causes of cholestasis including genetic, metabolic, inflammatory and dru
'"/>




Page: 1 2 3

Related medicine news :

1. First Vaccine Designed for Africa Cleared for Testing in Humans
2. Ajanta Launches Worlds First Once-A-Day Nimesulide Oral Formulation
3. First human clone is near
4. First Artificial Heart patient has Major setback
5. First head-to-head trials of once weekly Fosamax and Actonel therapies
6. WHO Declares Vietnam First Country to Control SARS
7. Russia Reports First SARS Case
8. Hope for First New Melanoma Treatment in Decades
9. First global SARS meet opens
10. Stanford Medical Center Implements The First Virtual Cardiac Ultrasound
11. Hyderabad To Have Asia’s First Catheter Making Uni
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: First Gene Chip Discovered Cincinnati Researchers

(Date:10/19/2014)... U.S. Government has initiated a major effort to ... However, a workgroup of nearly 40 Alzheimer,s researchers ... U.S. Government,s National Plan to Address Alzheimer,s Disease ... and adequately funded in order to successfully achieve ... workgroup to enlarge and strengthen the Plan are ...
(Date:10/19/2014)... October 19, 2014 When patients and their ... Hospital and turn the corner to face the Hummingbird Gift ... hospital volunteers to sell there. There’s unique home décor. Cooking ... so obvious, though, is the importance this small gift shop ... Tappahannock and Northern Neck community of the future. , ...
(Date:10/18/2014)... NY (PRWEB) October 19, 2014 Bon ... specializing in long-term and rehabilitation care in the Riverdale ... G. Beato, chief executive officer, was honored by New ... the CHA Corporate Alumni award at their 30th Annual ... degree in healthcare administration from New Jersey City University ...
(Date:10/18/2014)... 2014 Asbestos Likely More Widespread Than ... more widespread than previously thought, with newly discovered sources ... asbestos-rich areas are in locations not previously considered to ... be presented at the Annual Meeting of the Geological ... 20 October. , “These minerals were found where one ...
(Date:10/18/2014)... October 18, 2014 Ticket Down is a reputable ... eased considerably for this year's World Series. , The ... World Series this year. This determined team has not made ... Francisco Giants have had better luck in terms of participating in ... 1933, 1922, 1921 and 1905. This team had a ...
Breaking Medicine News(10 mins):Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6Health News:Riverside Tappahannock Hospital Capital Campaign Gets Boost From Community Through Gift Shop 2Health News:Riverside Tappahannock Hospital Capital Campaign Gets Boost From Community Through Gift Shop 3Health News:Carlos G. Beato Honored by New Jersey City University’s Council on Hispanic Affairs (CHA) 2Health News:Carlos G. Beato Honored by New Jersey City University’s Council on Hispanic Affairs (CHA) 3Health News:Asbestos Likely More Widespread Than Previously Thought 2Health News:Asbestos Likely More Widespread Than Previously Thought 3Health News:2014 World Series Tickets: Giants vs. Royals World Series Ticket Prices Have Eased Substantially 2
... S.C. accident could help other communities take necessary steps , , ... in 2005, a freight train with three tanker cars -- ... a parked locomotive in the center of Graniteville, S.C., a ... , One tank ruptured during the 2 a.m. collision, releasing ...
... The Healthcare Communication &,Marketing Association (HCMA) today ... will take place at the new Westin Hotel ... the first time, the event will focus on ... Leaders from,medical device, pharmaceutical, biotechnology, diagnostics and ...
... (Nasdaq: GHDX ) today announced the appointment ... president and chief operating officer,Popovits is now the president ... Cole has been appointed as chief operating officer and ... reporting to Popovits. , "Kim,s ...
... 8 Bill Germanakos, the 4th-season winner in the ... will be the special guest at two weight management ... Mansfield Medical Centers. The workshops, hosted by Methodist Weight ... people who want to make a healthy change through ...
... Organ Donors and Provide the Gift of LifeNEW YORK, ... pop band 98 Degrees, kicked off 2009 with a ... sign up today to become organ donors offering the ... the celebrity spokesperson for the newly formed Heather Trew ...
... Professionals are asked to do more with less than ever before. But ... to do? Learn how to put together a rock solid business case ... technology can pay for itself (and then some) in the first year. ... ...
Cached Medicine News:Health News:Preparing for a Chlorine Gas Disaster 2Health News:Preparing for a Chlorine Gas Disaster 3Health News:The Healthcare Communication & Marketing Association Announces June 2009 Conference and IN-AWE and Delta Awards Ceremony 2Health News:Genomic Health Announces Management Changes and New Responsibilities 2Health News:Genomic Health Announces Management Changes and New Responsibilities 3Health News:Genomic Health Announces Management Changes and New Responsibilities 4Health News:Methodist Weight Management Institute Brings NBC's 'Biggest Loser' to Dallas and Mansfield 2Health News:Methodist Weight Management Institute Brings NBC's 'Biggest Loser' to Dallas and Mansfield 3Health News:Jeff Timmons and the Heather Trew Foundation Join Forces to Promote Organ Donations 2Health News:Now, More Than Ever, Automating Compensation Planning Is A Good Financial Decision 2Health News:Now, More Than Ever, Automating Compensation Planning Is A Good Financial Decision 3
(Date:10/16/2014)... -- Eight finalists, all representing outstanding innovation in pediatric ... for a chance to compete for one of two ... Second Annual Pediatric Surgical Innovation Symposium hosted by ... 24, 2014. Selected from a competitive field ... internationally, the finalists are: , Creative ...
(Date:10/16/2014)... , Oct. 16, 2014   NuVascular ... process to create new medical devices that help ... Inc., the company uses cutting-edge nanotechnology that would ... kidney diseases.  The platform technology ... result of $6.6 million in funding obtained from ...
(Date:10/16/2014)... 2014 Ninety percent of children and adults ... times or failed to respond to standard therapies went ... CTL019, developed at the Perelman School of Medicine at ... The New England Journal of Medicine ... preliminary findings presented at the American Society of Hematology,s ...
Breaking Medicine Technology:Finalists for Children's National Health System pediatric medical device competition announced 2Finalists for Children's National Health System pediatric medical device competition announced 3Finalists for Children's National Health System pediatric medical device competition announced 4Nanotechnology Venture Targets Arterial, Heart and Kidney Diseases 2Nanotechnology Venture Targets Arterial, Heart and Kidney Diseases 3Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 2Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 3Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 4Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 5Personalized Cellular Therapy Achieves Complete Remission in 90 Percent of Acute Lymphoblastic Leukemia Patients Studied 6
... Inc. (Nasdaq: BNVI ), a pharmaceutical company focused ... for women,s health and cancer, today announced the pricing of ... 30,031,200 units at a price per unit of $1.00 for ... of one share of common stock and a warrant to ...
... Information Systems ("SIS"), a leader in perioperative ... successfully completed the healthcare industry,s week-long interoperability ... Connectathon. (Logo: http://photos.prnewswire.com/prnh/20080722/SISLOGO) ... industry,s largest interoperability testing event designed to ...
Cached Medicine Technology:Bionovo Announces Pricing of Follow-on Offering of Common Stock and Warrants 2Bionovo Announces Pricing of Follow-on Offering of Common Stock and Warrants 3Surgical Information Systems Completes IHE North American Connectathon 2
The Soft-Touch Timeter® Flowmeter is durable, long-lasting and easy to maintain. Timeter ® by Allied Flowmeters: Quality Plus Value....
The Soft-Touch Timeter® Flowmeter is durable, long-lasting and easy to maintain. Timeter ® by Allied Flowmeters: Quality Plus Value....
... line of flowmeters, available in oxygen, ... They are all available in a ... your application. With color coded labels ... in use, the Amvex Flowmeter is ...
... Amvex offers a complete line ... heliox and CO 2 . They ... of calibrations to best suit your ... dials specific to the gas in ...
Medicine Products: