Navigation Links
Fingerprinting prostate cancer

Two new genes which are active in prostate cancer have been identified by US researchers. At a molecular level, cancer tissue differs markedly from normal healthy tissue in its pattern of gene activity. Researchers have now developed the tools that can visualise analyse these 'molecular fingerprints' that characterise the cancerous cell. Using microarray technology, it's now possible to analyse thousands of genes in one experiments.//

Doctors at the University of Michigan have now produced the first ever molecular fingerprint of prostate cancer. They examined more than 700 prostate tissue samples from more than 50 men - covering normal tissue, tissue with benign change, and also tissues from both localised and aggressive prostate cancer. They found that more than 200 genes were expressed differently between normal and cancer tissue. Of these, some are already known to be involved in cancer, while others were completely new.

Of particular interest were two genes - hepsin and pim-1. The highest levels of hepsin were found in pre-cancerous tissue just before cancer develops, and the lowest in benign prostate tissue. Hepsin play a main role in tumour development. Pim-1, a known cancer-causing gene, was also highly expressed in prostate cancer tissue. Levels of hepsin and Pim-1 were significantly linked to prognosis, when the men's clinical histories were checked.

The researchers say that the discovery of prostate cancer's molecular fingerprint could lead to many new diagnostic tests. These could offer more to the patient than the current PSA (prostate specific antigen) test and can be used as a useful diagnostic tool.


'"/>




Page: 1

Related medicine news :

1. Better prostate cancer detection
2. Protective effects of tomatoes in prostate cancer
3. Early detection of prostate cancer
4. No link between blood groups and prostate cancer
5. Cure for osteoporosis in prostate cancer patients
6. Novel biopsy technique for prostate cancer
7. New diagnostic marker for prostate cancer
8. Inadequate proof to justify routine prostate screen
9. Combination regime may work against prostate cancer
10. Lifestyle linked to prostate cancer risk
11. Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many of ... beholder, according to experts who offered insights and commentary in the current issue of ... full issue, click here . , For the American Society of Clinical Oncology ...
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
(Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
(Date:6/23/2016)... Tenn. , June 23, 2016 /PRNewswire/ ... automating, integrating and transforming the patient payment ... of several innovative new products and services ... of its revenue cycle offerings. These award-winning ... more efficient workflows, remain compliant in an ...
Breaking Medicine Technology: