Navigation Links
Feeding channel created by malaria parasite - a new target for ,,malaria treatments

Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce.

The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Malaria kills more than one million people each year, most of them under age 5, and the disease is becoming resistant to many of the drugs used to treat it. This important finding provides a new target for potential new malara treatments. In addition to causing enormous human suffering, malaria impedes the economic development and stability of many developing countries. This discovery is an important step forward in our understanding of malaria and the search for new interventions to reduce the burden of this devastating disease.

P. falciparum is transmitted through the bite of mosquitoes infected with the parasite. After the malaria parasite infects a human red blood cell, it must get many nutrients-proteins, sugars and precursors for DNA-to survive and grow. While it obtains some of these by digesting the red blood cell's hemoglobin, it must get the rest from outside the cell. The parasite creates tiny channels in the red blood cell membrane, through which it can absorb nutrients. In fact, each infected red blood cell have a thousand or more such channels, which are not present on normal, uninfected red blood cells. For malaria, it is not clear whether the parasite creates the channels by changing a protein in the cell membrane or by trafficking a new protein made in the malaria parasite to the cell membrane for subsequent icorporation. With this information, researchers may be better able to develop drugs to cut off the parasite's nutrient supply. In addition, any new protein that the parasite adds to the red blood cell surface might be an attractive can didate for vaccine development.
'"/>




Related medicine news :

1. Breast Feeding prevents obesity later on in life
2. The Beneficial Effects Of Breast Feeding
3. Healthy Feeding Guidelines for Children Ages 0 to 24 Months Issued
4. Winning Formula For Mother and baby - Breast Feeding!
5. Breast-Feeding In Public – Will The Society Accept It
6. Breast Feeding Alone can Reduce Infant Mortality Rates
7. Breast Feeding Alone Can Reduce Infant Mortality Rates: Govt
8. Liberated British Mothers Want No Restriction on Breast Feeding In Public
9. Breast Feeding - The Key in Fighting Child Mortality in Africa
10. Breast-Feeding May Reduce Childhood Obesity
11. Babies with Cleft Conditions, Pierre Robin Sequence May Need Extended Treatment for Poor Feeding Skills
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
(Date:6/24/2016)... Plano, TX (PRWEB) , ... June 24, 2016 , ... ... taking part in Genome magazine’s Code Talker Award, an essay contest in which patients ... for an award to be presented at the 2016 National Society of Genetic Counselors ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016  American ... function testing company, is now able to perform sophisticated lung assessments ... ndd Medical Technologies , Inc. Patients are no ...  Thanks to ndd,s EasyOne PRO ® , ARL patients like Jeanne ... needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
Breaking Medicine Technology: