Navigation Links
Faulty gene increases risk of breast cancer in relatives of patients

A report published in The Lancet has implicated a defective gene called Chek2 in the development of breast cancer in women who have relatives with the same condition. It is generally accepted among researchers that the faulty gene increases the risk of developing breast cancer// twice over. But the new research says that a variant of the gene could be responsible for placing relatives at risk as well. In the current study, researchers at the London School of Hygiene and Tropical Medicine tracked 469 patients with bilateral breast cancer for the Chek2 gene variant. They then monitored the risk in first-degree relatives of carriers and non-carriers.

They found that relatives of the women who had bilateral breast cancer and a normal Chek2 gene had a 23.8 percent risk of developing cancer as compared to the accepted risk of 7.9 percent. However, women who had relatives with bilateral breast cancer plus had the defective Chek2 gene had a risk of 58.8 percent by the time they reached 80 years of age. The variant or the mutant form of the Chek2 gene has been called Chek2*1100delC. 'Roughly 2,000 bilateral breast cancer cases are diagnosed in the UK every year, of whom 2% are carriers of Chek2*1100delC. Testing for Chek2*1100delC in women with a family history of breast cancer, especially those with a bilaterally affected first-degree relative, could be clinically useful for predicting personal risks,' said Olivia Fletcher, a member of the team of researchers which was lead by Professor Julian Peto.
'"/>




Page: 1

Related medicine news :

1. Rare Bone Disease Traced To Faulty FOP Gene
2. Cellular System Causing Destruction Of Faulty Proteins In Cystic Fibrosis Identified
3. Human gene number increases
4. Stress response increases suicide risk
5. Sleep apnoea increases post-operative risks
6. Vaginosis increases risk of miscarriage
7. Serotonin increases stroke risk
8. Depression increases heart attacks
9. Excess vitamin A increases fracture risk
10. High vitamin A increases risk of hip fractures
11. Less sleep increases mortality rates
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... , ... May 27, 2016 , ... This campaign aims ... stroke, which we as a society can control and change. , As nearly 795,000 ... every 40 seconds within the United States. Plus, with an estimated 129,000 of these ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses ... human interest stories, courtesy of leaders in the nursing and health care industry. ... from leading advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett ...
(Date:5/26/2016)... ... ... last week’s media reports hinting at a June rate hike after the Federal Reserve’s ... interest rate increase, according to Rajeev Dhawan of the Economic Forecasting Center at Georgia ... (FOMC) dot charts are of interest to the press for their noise potential,” Dhawan ...
(Date:5/26/2016)... ... May 26, 2016 , ... Intalere, the healthcare industry ... for its inaugural Member Conference at the Paris Hotel in Las Vegas, Nev., ... health of America’s healthcare providers. , The conference was highlighted by the announcement ...
(Date:5/26/2016)... ... , ... The Woodlands at John Knox Village , Florida’s first Life ... living and healing, celebrated its grand opening, today. The Woodlands at John Knox Village ... Empowered Staff. , “This is an incredibly fulfilling time for John Knox Village as ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... Texas , May 25, 2016 ... the issuance to it by the US Patent ... The company,s technology includes proprietary processes for electronic ... for health and wellness programs, HIPAA compliance and ... "Our technology ...
(Date:5/24/2016)... AMSTERDAM , May 24, 2016 ... aplicación médica para ayudar a los médicos a compartir ... los pacientes a escala mundial. Profesionales médicos de Europa, ... ya se han apuntado a la aplicación, que combina ... en un entorno totalmente seguro. Educación   ...
(Date:5/24/2016)... LAWRENCE, Mass. , May 24, 2016  NxStage ... medical technology company focused on advancing renal care, today ... Officer, plans to participate in the following schedule of ... will be made available at http://ir.nxstage.com/ . ... Jefferies Healthcare Conference NY, NY           Friday, ...
Breaking Medicine Technology: