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Fatigue After Liver Transplantation Does Not Lessen With Time

Patients who undergoing Liver transplant reportedly experience physical fatigue and reduced activity rather than mental fatigue and reduced motivation//. In a new study on this fatigue experienced by patients after liver transplantation, it was found that to be a major problem that does not seem to improve with the passage of time. The results of this study was published in the June 2006 issue of Liver Transplantation that is the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS). John Wiley & Sons, Inc. publishes the journal for the societies. The same is also available online through Wiley InterScience at 'http://www.interscience.wiley.com/journal/livertransplantation.'

Although fatigue is common in end-stage liver disease and can even contribute to the need for a liver transplant, few studies have been conducted on fatigue after liver transplants take place. In the current study, researchers led by Rita van den Berg-Emons, Ph.D. of the Department of Rehabilitation Medicine at the Erasmus Medical Center in Rotterdam, The Netherlands, assessed 96 liver transplant patients who visited the hospital's outpatient clinic between February and June 2003. The patients were given a series of self-administered questionnaires: the Fatigue Severity Scale (FSS) measured fatigue severity; the Multidimensional Fatigue Inventory (MFI-20) measured the nature of fatigue; two additional questionnaires measured the patients' disability level and their health-related quality of life (HRQoL). In addition, the researchers assessed patients' age, gender, reason for having the transplant, time since the transplant took place, and the number of immunosuppressive agents they were taking.

The results showed that 66 percent of the patients were fatigued, 44 percent were severely fatigued, and there was no indication that fatigue lessened over time. 'This is the first study to
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