Navigation Links
Fathering Best Done In Early Years

Recent research has revealed that men reaching fatherhood late in life may not be such a good idea after all because of the genetic damage that increases with age//.

US scientists conducted a study of sperm from around 100 healthy, non-smoking men aged 22 to 80 and found a prevalence of certain genetic damage increasing with age. This in turn can be manifested as symptoms such as infertility, difficulty in their partners becoming pregnant miscarriages and an increased risk of the offspring inheriting genetic diseases such as dwarfism.

‘There is consequence to delaying fatherhood,’ said Andrew Wyrobek, lead researcher of the study and a biophysicist at the Lawrence Livermore National Laboratory in California. ‘The probability of infertility goes up, the risk of abnormal pregnancy goes up and the risk of dwarfism goes up, and perhaps other genetic diseases as well.’

The study revealed that with increased age there appeared to be increased DNA breakage in sperm, increased conditions that lead to infertility or miscarriages. In addition it was found that gene mutation causing dwarfism were also increased.

According to the researchers compared with men in their 20s, a 50-year-old has a 34 per cent higher risk of producing a child who is a dwarf, while an 80-year-old's risk is 85 per cent higher.

However, chromosome number related diseases like Down syndrome, Turner syndrome and triple X syndrome appeared to be unaffected by male age.

‘We know that women have a biological time clock with an increase in risk of miscarriage and producing children with trisomy (an extra chromosome) as women age, and with a seemingly abrupt end of fertility around perimenopause,’ said co-lead author Dr. Brenda Eskenazi of the School of Public Health at the University of California, Berkeley.

‘Our research suggests that men, too, have a biological time clock - only it is different,’ Eskenazi said in a statement. ‘Men seem t o have a gradual rather than an abrupt change in fertility and in the potential ability to produce viable healthy offspring.’

The study of paternal age is important considering the fact that paternal age has been rising steadily over the past few decades. Since 1980, there has been about a 40 per cent increase in 35-to 49-year-old men fathering children, and a 20 per cent decrease in fathers under 30. Studies have also shown that it takes longer for older men to conceive, even when the age of the mother is considered.

Commenting on the size of the study, Toronto urologist Dr. Kirk Lo said that with fewer than 100 subjects covering such a wide age range, the findings were open to interpretation.

‘In older men, they may have increased sperm DNA fragmentation and that could affect fertility,’ he said. ‘But is this due to environmental factors or is it intrinsic to aging? It's difficult to say.’

The results of the study have been published in the online edition of the Proceedings of the National Academy of Sciencs.


'"/>




Related medicine news :

1. Early detection of prostate cancer
2. Early detection of heart attack
3. Early puberty linked to nutrition
4. Early Clue to Down Syndrome
5. Early delivery can prevent cancer
6. Early puberty more resistance
7. Early menopause- The cause
8. Early menopause- The cause
9. Early Warning System For Breast Cancer
10. Early therapy aids eyesight
11. Early detection of colorectal cancer may be hindered by coloured toilet disinfectants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
(Date:10/12/2017)... ... 12, 2017 , ... On Saturday, October 21, the Health & Wellness Center ... to raise money for the American Heart Association Heart Walk. Teams of up to ... together to keep their treadmills moving for 5 hours. Treadmills will start at 7:00 ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... the latest in wound care advancements to physician colleagues, skilled nursing facility medical ... titled, "Navigating the Treacherous Waters of Wound Care." , "At many of these ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... , Oct. 6, 2017   Provista, a ... than $100 billion in purchasing power, today announced a ... information. The Newsroom is the online home ... trends, infographics, expert bios, news releases, slideshows and events. ... to a wealth of resources at their fingertips, viewers ...
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease Control ... of October . PhysicianOne Urgent Care is helping communities across ... NY , by offering no-cost* flu shots through the end of ... by certain health insurance regulations. ... best time to get a flu shot is by the end of ...
(Date:10/2/2017)...  Eli Lilly and Company (NYSE: LLY ... quarter of 2017 on Tuesday, October 24, 2017. Lilly ... with the investment community and media to further detail ... will begin at 9 a.m. Eastern time. Investors, media ... of the conference call through a link that will ...
Breaking Medicine Technology: