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Fat Cells Can Trigger Heart Diseases

Lead researcher Dr Lynn Stoll said, that the fat cells surrounding coronary arteries might ultimately prove to be an important link between obesity, type II diabetes, and coronary artery disease, which are all increasing at an epidemic rate. He suggested that on trying to understand better as to how the epicardial adipocytes sense and respond to inflammation and ischemia could lead to new, rational design for therapies on heart disease.

Stating that it is an interesting piece of research, Professor Jeremy Pearson, associate medical director of the British Heart Foundation, said that though it had been recognised for several years that fat cells stored up around the body secrete hormones that affect blood vessel function, this is the first time that researchers have paid careful attention to fat cells lying close to blood vessels in the heart.

He said that Dr Stoll's results strongly suggest that the probability of these cells being important regulators of blood vessel growth and repair might have previously gone unrecognised. He suggested that they should in future investigate some more to try and get a better understanding on the role the cells play in the development of coronary heart disease.


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