Navigation Links
Fat Cell Protein Hits Type-2 Diabetes

According to researchers a protein found in human fat cells may become key to the development of future treatments for type-2 or adult onset diabetes. According to Dr. Lucino Roseveltte, professor of medicine at 0the Hopkins College of Medicine in New York , there are molecules produced by the fat cells, the adipose tissue//, circulating throughout the body and affecting the functions of different organs. Their research identifies one very significant protein, Acpr30, that is made in fat cells--- and made less abundantly in the fat cells of obese people and animals -- that significantly affects insulin action in the liver.

Type-2 diabetes affects between 2 million and 6 million Americans and is rising in epidemic proportions as obesity rates also rise. Type-2 diabetes accounts for 70 percent to 90 percent of all diabetes cases. The majority of people who have type-2 diabetes are obese, about 60 to 80 percent. According to him the idea has been developed that the adipose cell where the fat is stored is also producing very active molecules that are really functioning as hormones. He said his research team found a very clear mechanism by which an increase or decrease in fat cell size, as happens in obese humans, might cause severe hepatic (liver) insulin resistance because less of a hormone-like protein, Acrp30, is secreted by the fat cell.

The researchers used a genetic approach in cells to generate an exact copy of the Acrp30 protein. They injected mice with Acrp30 until they doubled the protein level. The question was that iIf we simply doubled the concentration of this adipose-derived hormone and then carefully measure the hepatic glucose production -- or action of insulin on the liver-- are we generating a significant effect?' The answer we found was a clear-cut'Yes, according to Roseveltte. What's really interesting about Acrp30 is that we know that it is missing or lower in obese people.

He said the study suggests just small in
'"/>




Page: 1 2

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fat Cell Protein Hits Type Diabetes

(Date:7/7/2015)... ... July 07, 2015 , ... Nationally-renowned attorneys ... their new website, the Invokana Ketoacidosis Lawsuit Center . The website provides ... a resource for persons wishing to learn more about Invokana lawsuits for kidney ...
(Date:7/7/2015)... ... July 07, 2015 , ... CSG Government ... been selected by the Department of Vermont Health Access to provide Quality Assurance ... System (MMIS) and Integrated Contact Center System project. , Vermont is implementing a ...
(Date:7/6/2015)... ... ... Respected southern California personal injury attorney Fernando D. Vargas has been honored ... has sharp legal skills as well as a superior commitment to client service. , ... a Top 10 Award from The National Academy of Personal Injury Attorneys (NAOPIA). , ...
(Date:7/6/2015)... ... July 06, 2015 , ... On June 22, 2015, Fox News in a report titled “ Female Hair Loss ... turn age 35 a quarter of all women in the U.S. will suffer from thinning ... stigmatized and rarely discussed. One woman, a former beauty queen, who was interviewed for the ...
(Date:7/6/2015)... (PRWEB) , ... July 06, 2015 , ... The Asian-Pacific ... in 2014. It is expected to grow at a CAGR of over 3.2 percent ... , The growth is likely to be mainly spurred by an anticipated launch of ...
Breaking Medicine News(10 mins):Health News:National Attorneys Launch Invokana Ketoacidosis Lawsuit Center 2Health News:National Attorneys Launch Invokana Ketoacidosis Lawsuit Center 3Health News:CSG Government Solutions Selected by the Department of Vermont Health Access to Provide Quality Assurance and Independent Verification and Validation Services 2Health News:Fernando D. Vargas Awarded Top Honors in Personal Injury Law for 2015 from Two Respected Independent Organizations 2Health News:Fernando D. Vargas Awarded Top Honors in Personal Injury Law for 2015 from Two Respected Independent Organizations 3Health News:The Stigma of Female Hair Loss and Hair Restoration Solutions 2Health News:APAC Rheumatoid Arthritis Therapeutics Market to Reach Value of USD 6.9 Billion by 2021, Says GBI Research in Its New Report Now Available at MarketPublishers.com 2
... , WASHINGTON, Aug. 26 Danaher Corporation ... Executive Officer, H. Lawrence Culp, Jr. will be presenting at ... on Wednesday, September 2, 2009 at 12:30 p.m. EDT. The ... the webcast will be available for one week following the ...
... , MCLEAN, Va., Aug. 26 MicroStrategy((R)) ... provider of business intelligence (BI) software, today announced that ... has selected MicroStrategy to improve its sales reporting and ... international pharmaceuticals company Boehringer Ingelheim. , , ...
... , MISSION, Kan., Aug. 26 Like ... new ways to operate cost-effectively and use tax dollars wisely. ... administration program. And effective October 2009, Kansas City-based COBRAGuard, Inc. ... , Of course, with every outsourcing situation, ...
... ... anti-aging . , ... -- Every morning women all across America wake up, head to the makeup mirror, and add ... is hailed by Allure magazine as one of the most influential beauty breakthroughs of the decade, ...
... , , NEW YORK, Aug. 26 ... applied to the government broadband stimulus fund to provide broadband access ... areas exist in all 50 states because they are not connected ... or too disperse and challenging to dig ditches and lay wires. ...
... , SOUTHAMPTON, Pa., Aug. 26 ... the "Company") BioMedical Systems Division, a product division in ... SRL for the delivery and installation of the first ... , Histria International is a "turn-key" ...
Cached Medicine News:Health News:Boehringer Ingelheim's Swiss Branch Improves Sales Reporting and Efficiency with MicroStrategy Software 2Health News:Boehringer Ingelheim's Swiss Branch Improves Sales Reporting and Efficiency with MicroStrategy Software 3Health News:State of Kansas Streamlines COBRA Administration With Innovative Web-Based Solution 2Health News:5 Simple Ways to Take 10 Years Off Your Face 2Health News:5 Simple Ways to Take 10 Years Off Your Face 3Health News:5 Simple Ways to Take 10 Years Off Your Face 4Health News:01 Data Center Applied to Provide Broadband Access to Healthcare Facilities in Unserved Areas 2Health News:Environmental Tectonics Corporation's BioMedical Systems Division Announces First BARA-MED(R) Monoplace Hyperbaric Chamber Sale in Romania 2Health News:Environmental Tectonics Corporation's BioMedical Systems Division Announces First BARA-MED(R) Monoplace Hyperbaric Chamber Sale in Romania 3Health News:Environmental Tectonics Corporation's BioMedical Systems Division Announces First BARA-MED(R) Monoplace Hyperbaric Chamber Sale in Romania 4
(Date:7/6/2015)... Ga. , July 6, 2015  EndoChoice Holdings, ... its second quarter 2015 financial results on Thursday, August ... EndoChoice will hold a conference call on Thursday, August ... results. The dial-in numbers are (866) 807-9684 for domestic ... webcast of the conference call will be available on ...
(Date:7/6/2015)... July 6, 2015  Nitin Tandon, M.D., UTHealth ... Memorial Hermann Mischer Neuroscience Institute at ... RNS® System technology into the skull of a ... of seizures – the first time this procedure ... "Epilepsy is a neurological condition that affects ...
(Date:7/6/2015)... 6, 2015 Mauna Kea ... multidisciplinary confocal laser endomicroscopy platform, announced today it ... Ministry of Health, Labor and Welfare (MHLW) ... the AQ-Flex 19 miniprobe.   Used ... miniprobe is comprised of a fiber-optic microscope that ...
Breaking Medicine Technology:EndoChoice to Report Second Quarter 2015 Financial Results on August 6, 2015 2Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 2Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 3Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 4Mauna Kea Technologies Receives Regulatory Approval for the AQ-Flex 19 Miniprobe in Japan 2Mauna Kea Technologies Receives Regulatory Approval for the AQ-Flex 19 Miniprobe in Japan 3
... REDWOOD CITY, Calif., Feb. 6, 2012 Cardica, Inc. (Nasdaq: ... fiscal second quarter ended December 31, 2011. Cardica,s management will ... to discuss the financial results and provide an update on ... progress on bringing our MicroCutter product line to the marketplace," ...
... 2012  A recent discovery by Van Andel Research Institute ... proposed drug therapies for glioblastoma – the most common ... The study, published in January in the ... , investigated glioblastoma models characterized by cell signaling activation ...
Cached Medicine Technology:Cardica Announces Fiscal 2012 Second Quarter Financial Results 2Cardica Announces Fiscal 2012 Second Quarter Financial Results 3Cardica Announces Fiscal 2012 Second Quarter Financial Results 4Cardica Announces Fiscal 2012 Second Quarter Financial Results 5Cardica Announces Fiscal 2012 Second Quarter Financial Results 6Discovery Predicts Patient Sensitivity to Important Drug Target in Deadly Brain Cancer 2
... TOPLOAD 620/0.01G, BX620S. Digital stability control, ... measure, piece counting and percent measure ... including date and time data from ... external weights (selectable from 200g to ...
Guaranteed leak-proof , Teflon coating is impervious to corrosive materials , Shock-resistant , NBS tolerances of accuracy , Thermometers are 225 mm long with an immersion length of 35 mm ...
The EK-H Series offer 10 selectable units of measure...
Guaranteed leak-proof , Teflon coating is impervious to corrosive materials , Shock-resistant , NBS tolerances of accuracy , Thermometers are 225 mm long with an immersion length of 35 mm ...
Medicine Products: