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Eyelid Spasm can Be Prevented by Coffee Drinking

According to a study published online ahead of print in the Journal of Neurology Neurosurgery and Psychiatry, People who drink coffee are less likely to develop an involuntary eye spasm called primary late onset blepharospasm, which makes them blink uncontrollably and can leave them effectively blind.

The effect was proportional to the amount of coffee drank and one to two cups per day were needed for the protective effect to be seen. The age of onset of the spasm was also found to be later in patient who drank more coffee 1.7 years for each additional cup per day.Previous studies have suggested that smoking protects against development of blepharospasm, but this Italian study did not show a significant protective effect.

Late onset blepharospasm is a dystonia in which the eyelid muscles contract uncontrollably; this starts as involuntary blinking but in extreme cases sufferers are rendered functionally blind despite normal vision because they are unable to prevent their eyes from clamping shut.

The study involved 166 patients with primary late onset blepharospasm, 228 patients with hemifacial spasm (a similar muscle spasm that usually begins in the eyelid muscles but then spreads to involve other muscles of the face) and 187 people who were relatives of patients. The second two groups acted as controls.

The participants were recruited through five hospitals in Italy and asked whether they had ever drank coffee or smoked and for how many years. They were also asked to estimate how many cups of coffee they drank and/or packs of cigarettes they smoked per day. The age of onset of muscle spasms was recorded for patients who experienced them and a reference age was calculated for each of the patients relatives based on the duration of the spasms in the other group.

Regression analysis was used to observe the relationship between coffee drinking and smoking on the development of blepharospasm.The authors say: Our f
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