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Extra hormone found to cut appetite by a third

g fat from being absorbed.

The British researchers recruited 24 people: 12 obese and 12 lean. Their food consumption was monitored twice, once after an intravenous dose of synthetic PYY and once after getting a harmless saline solution. Two hours later, they were given a large buffet lunch.

After the PYY dose, the obese ate 30 percent fewer calories than they did after the dummy solution. The lean people ate 31 percent less. The PYY continued to curb their appetites for 12 hours, with the obese eating 26 percent less and the lean eating about 34 percent less, based on food diaries they kept.

The PYY did not affect food consumption from 12 hours to 24 hours after the infusion. Without the extra dose, PYY levels were lower in the obese participants than in the lean, but the researchers said it is not known whether that is a cause of obesity or a consequence.

If it's a consequence of obesity, it would explain why once people become overweight, it is very difficult for them to reverse it. They don't feel as feel as full after food as normal people do as a result of their obesity.
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