( According to a leading paediatric exper...)Experts Need to Include Children in Research,Health

According to a leading paediatric expert,Scientists will only make real breakthroughs in childrens medicine if they include children in research programmes as well as adults .

Professor John Warner was speaking today at the opening of the Paediatric Research Unit, the UKs first unit solely devoted to paediatric clinical research.

The unit is run by researchers from Imperial College London and St Marys Hospital, and it is based next to the hospitals paediatric wards in Paddington.

Professor Warner, who is Chair in Paediatrics and Head of the Department of Paediatrics at Imperial College and consultant paediatrician at St Marys Hospital, explained that researchers should be designing therapies specifically for children and their problems, rather than scaling down treatments that were created for adults.

In many respects the makeup of children differs from that of adults: they have different metabolisms; their organs are not as mature as adults; and diseases can behave differently in childrens bodies.

To create the best therapies for children we need to include them in our research, said Professor Warner. A lot of paediatricians work doesnt have much of a scientific evidence base and we prescribe drugs by extrapolating from what we know about adult bodies.

We have a desperate need to understand precisely how childrens bodies work so that we can custom-design therapies for them and their problems.

Researchers in the new unit will be investigating many areas including paediatric allergies and how these can be prevented; sleep disturbance and how this affects health and behaviour; new treatments for acute and chronic chest disorders such as bronchiolitis and asthma.

They will also be looking at infectious diseases and immunisation; new treatments for neuromuscular diseases such as Duchenne muscular dystrophy; and prevention of the complications of sickle cel
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