Navigation Links
Excess Cdk5 Enzyme Can Harm Brain

A research conducted by the Howard Hughes Medical Institute, the National Institute of Mental Health and the Harvard Medical School has revealed that a brain enzyme plays a prominent role// in maintaining and developing learning and memory. If the enzyme is present in high levels, then it can have adverse effects on the brain. The tests were conducted on mice. The Cdk5 enzyme also plays an important role in the death of neurons in disorders like the Alzheimer's disease.

According to the researchers' studies, increased levels of Cdk5, as well as increased levels of a regulatory protein called p25 that is known to hyper-activate Cdk5, had been found in the brains of patients suffering from Alzheimer’s. In the study, the researchers used mice in which they could switch on p25 at will in the brain's learning and memory center, the hippocampus. It was found that while in the mice in which p25 was switched on for only two weeks, actually enhanced learning and memory, in contrast, mice in which p25 had been switched on for six weeks showed impaired learning and memory in certain tasks.

The researchers said that this indicated that elevated levels of p25 impaired learning and memory. This indicates that transient p25 production facilitated learning, whereas the ability to form new memories was impaired by prolonged p25 expression, according to the researchers said. The study showed that it was possible that chronic exposure to Alzheimer’s risk factors would increase the p25 to a level that would contribute to neural loss.

The researchers said that the increase in p25 levels might be a mechanism to compensate for the damage from such diseases like Alzheimer’s. This may cause the enzyme, whose work it was to stop degeneration, actually quicken the process. The evidence that is provided by the study is that the p25 generation might be a compensatory phenomenon to enhance neuroplasticity. These mice may also serve as a model whereby a facto
'"/>




Page: 1 2

Related medicine news :

1. Excessive use of antibiotics for sore throat
2. Excess vitamin A increases fracture risk
3. Excess Weight Can Affect Individuals as They Age
4. Excess physical activity can induce stress fracture in adolescent girls
5. Good News For Those Suffering From Excessive Sweating
6. Excessive Day time sleep may be linked to depression or diabetes
7. Excess Intake of Alcohol Results in Permanent DNA Damage.
8. Excess of anything, even Vitamin D found to be harmful
9. Excessive Belly Fat Could Increase Risk Of Gallstones In Women
10. Doctors Drained Excess Fluids From Sharons Abdominal Cavity
11. Oral Medicine Found To Remove Excess Iron in the Body
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Excess Cdk5 Enzyme Can Harm Brain

(Date:7/29/2014)... 2014 The Law Offices of Michael Cordova ... Hope, a non-profit organization providing grief camps for kids, teens, ... and suffering our clients experience from the death of a ... an organization like Stepping Stones of Hope, as they provide ... Stones of Hope also includes a monthly support group and ...
(Date:7/29/2014)... record the severity and regularity of their pain is ... , A new approach to the treatment of headaches, ... and is being led by Professor Paul Martin from ... He has developed an approach designed to enable people ... Learning to Cope with Triggers (LCT). , Using a ...
(Date:7/29/2014)... of cancer is to surgically remove the tumor. The ... surgeon may fail to extract the entire tumor, leading ... researchers at the University of Pennsylvania have established a ... in the patient, increasing the likelihood of a positive ... accumulates in cancerous tissues much more so than normal ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 A new ... during the 2014 Society for Cardiovascular Angiography and Interventions ... released this week. The videos review the benefits of ... services for the cardiac catheterization laboratory from the perspective ... the first video, Jane Kiah, MS, RN, Director of ...
(Date:7/29/2014)... boys with fragile X syndrome tend to decline ... of the inherited disorder to date has found. ... social and practical skills, including communication, socialization, and ... dressed. In this study, socialization emerged as a ... that it did not decline as much as ...
Breaking Medicine News(10 mins):Health News:The Law Offices of Michael Cordova is Sponsoring Stepping Stones of Hope, a Non-Profit Organization Providing Grief Camps for Kids, Teens, Adults, and Families 2Health News:Penn team makes cancer glow to improve surgical outcomes 2Health News:Penn team makes cancer glow to improve surgical outcomes 3Health News:Accreditation for Cardiovascular Excellence (ACE) Launches 3-Part Video Series: The Cost/Benefit of ACE Accreditation; ProMedica Toledo Hospital Achieves Accreditation 2Health News:Accreditation for Cardiovascular Excellence (ACE) Launches 3-Part Video Series: The Cost/Benefit of ACE Accreditation; ProMedica Toledo Hospital Achieves Accreditation 3Health News:Socialization relative strength in fragile X longitudinal study 2
... up with a remarkable discovery. Scientists there, have found ... have added benefits. Sildenafil and other drugs that help to ... chemical messenger seem to help in unveiling cancer cells. ... by that the immune system. , The ...
... Dr. Reddy's Laboratories will launch a first-of-its-kind pill to ... it was announced Thursday. // ,The company ... New Zealand, for trials of the groundbreaking 'polypill' that ... to treat heart ailments. , ,India records nearly ...
... multi vitamin supplements have a healthier diet and lifestyle ... ,Researchers led by Lindsay Reaves of the University of ... weight, diet and health behaviour of over 2,500 US ... , ,The study, which appeared in the December ...
... areas as part of a government plan to reach healthcare ... government has released initial funds to the tune of Rs. ... in rural areas. ,According to a health ministry ... Health Mission (NRHM) scheme for 2006-07. ,The ...
... is admissible to Orthopaedically Handicapped/Paraplegic persons, Completely Blind, ... (both afflictions together in the same person). Except ... all classes to other categories. Deaf & Dumb ... and First Class. Concession is granted in all ...
... The American Dental association announced on the 9th of November, ... preparation of infant formulation. // ,The dentists are concerned ... might be disastrous as instead of protecting teeth it might ... lead to weakened bones and even bone cancer boys. ...
Cached Medicine News:Health News:Impotency Drugs Help to Unmask Cancer Cells 2Health News:Dr. Reddy's To Launch 'Polypill' For Treating Heart Disease 2
(Date:7/29/2014)... N.J. , July 29, 2014 Regado ... company focused on the Phase 3 clinical development of ... controllable antithrombotic drug system, today announced that it will ... Tuesday, Aug. 12, 2014, at 8:30 a.m. EDT to ... highlights. Interested participants and investors may access ...
(Date:7/29/2014)... 2014 Edwards Lifesciences Corporation (NYSE: EW ... and hemodynamic monitoring, today reported net income for the quarter ... diluted share, and non-GAAP net income of $94.0 million, or ... a year earlier was $93.3 million, or $0.81 per diluted ... per diluted share.  Net sales for the ...
(Date:7/29/2014)... New technology in the form of a ... see and assess brain tissue more clearly while treating ... who released their findings today at the Society of ... Colorado Springs, CO. ... a specialty that facilitates stroke treatment by navigating a ...
Breaking Medicine Technology:Regado Biosciences to Provide Second Quarter 2014 Financial Results and Corporate Highlights 2Regado Biosciences to Provide Second Quarter 2014 Financial Results and Corporate Highlights 3Edwards Lifesciences Reports Strong Second Quarter Results 2Edwards Lifesciences Reports Strong Second Quarter Results 3Edwards Lifesciences Reports Strong Second Quarter Results 4Edwards Lifesciences Reports Strong Second Quarter Results 5Edwards Lifesciences Reports Strong Second Quarter Results 6Edwards Lifesciences Reports Strong Second Quarter Results 7Edwards Lifesciences Reports Strong Second Quarter Results 8Edwards Lifesciences Reports Strong Second Quarter Results 9Edwards Lifesciences Reports Strong Second Quarter Results 10Edwards Lifesciences Reports Strong Second Quarter Results 11Edwards Lifesciences Reports Strong Second Quarter Results 12Edwards Lifesciences Reports Strong Second Quarter Results 13Edwards Lifesciences Reports Strong Second Quarter Results 14Edwards Lifesciences Reports Strong Second Quarter Results 15Edwards Lifesciences Reports Strong Second Quarter Results 16Edwards Lifesciences Reports Strong Second Quarter Results 17Edwards Lifesciences Reports Strong Second Quarter Results 18Edwards Lifesciences Reports Strong Second Quarter Results 19Edwards Lifesciences Reports Strong Second Quarter Results 20Edwards Lifesciences Reports Strong Second Quarter Results 21Edwards Lifesciences Reports Strong Second Quarter Results 22Edwards Lifesciences Reports Strong Second Quarter Results 23Edwards Lifesciences Reports Strong Second Quarter Results 24Edwards Lifesciences Reports Strong Second Quarter Results 25New Technology May Improve Visualization Of The Brain During Stroke Treatment 2New Technology May Improve Visualization Of The Brain During Stroke Treatment 3
... CHICAGO, June 29, 2011 UBM Canon,s publishing group,s leading ... ), Medical Device and Diagnostic Industry ( ... Developments in Materials for Medical Applications " on May 24, ... virtual conference and trade show offered the opportunity to learn ...
... AUSTIN, Texas, June 29, 2011 Ascension Orthopedics, Inc., the ... the PyroTITAN™ Humeral Resurfacing Implant in Geelong, Australia by Richard ... "The patient was a 57-year-old, active male with ... by a fall from a mountain bike and not improved ...
Cached Medicine Technology:UBM Canon's Virtual Event Dedicated to Developments in Materials for Medical Applications 2UBM Canon's Virtual Event Dedicated to Developments in Materials for Medical Applications 3Ascension Orthopedics Implants PyroTITAN™ in Geelong, Australia 2
... The Hancock® II bioprosthesis from ... years of proven clinical experience. ... the freedom from structural valve ... and mitral bioprostheses is substantially ...
... bioprosthesis from Medtronic has more ... clinical experience. Worldwide clinical studies ... structural valve deterioration with Hancock® ... is substantially better than results ...
Attain Venogram Balloon Catheter....
... cardioverter defibrillators (ICDs) are designed to treat ... (SCD) due to arrhythmia. The size and ... is designed to facilitate ease of insertion ... 2 system incorporates Guidant's proprietary RHYTHM ID ...
Medicine Products: