Navigation Links
Even Normal Doses Of Tylenol Could Damage Liver

People who repeatedly take acetaminophen for their aches and pains could be at an increased risk for liver damage, according to the findings of a new study// .

Researchers said that patients who repeatedly approached the maximum recommended daily dose of acetaminophen showed abnormalities in blood tests, which could indicate liver damage. They added that initially they had come across liver damage in patients who took opioid hydrocodone plus acetaminophen. Previous assumption had been that it was hydrocodone that was the culprit for liver damage, but they were surprised to find that the damage was caused by acetaminophen.

"This clearly showed, much to our jaw-dropping surprise, that it had nothing to do with the opiate," said Dr. Paul Watkins, lead author of the study. "It was a previously unrecognized but pretty remarkable effect of acetaminophen alone when taken as directed for four days."

He added that acetaminophen, which is commonly available as Tylenol, has an established safety record, so the findings were unexpected. "No one should ever take a drug they don't need," he said. "But this study is not a reason to stop taking acetaminophen if you need it."

The findings of the study are published in the July 5 issue of the Journal of the American Medical Association. 145 healthy adults were given either a placebo or one of three acetaminophen/opioid combinations, or acetaminophen alone for two weeks.

The researchers found that 31 percent to 44 percent of patients in the treatment groups had a maximum ALT measurement equal to thrice the normal value. ALT is blood aminotransferase, which indicted liver disease.

"It was so unbelievable that I am conducting an ongoing study with 50 people," Watkins said. "That's not in the JAMA paper, but we're finding that it verifies the findings. Since we have decades of experience and know the safety of acetaminophen, are the tests as good as we thought they w ere? Maybe they're not good predictors as to which drugs are going to have liver problems."
'"/>




Related medicine news :

1. Anti-Cancer Drug Restores Normal Cell Growth
2. Normal Blood Pressure Could Add Over 5 Years To Your Life
3. Language Delays May Not Be Normal In Children
4. Normal Delivery Is Better Than Caesarean Birth
5. Clinic Helps Women Lead Normal Lives
6. Premature Babies Can Lead Normal Lives
7. Health Services Returning To Normal
8. Rahul Mahajans Condition Improving; Vital Parametres Normal
9. Normalcy Returns To AIIMS; Venugopal Attends Office
10. Fiber And Fruit Key To Normal Weight
11. Craniofacial Surgery Gives Tijuana Teen Chance to be Normal Kid
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/10/2018)... , ... December 10, 2018 , ... ... the "100 hospitals and health systems with great heart programs." , The hospitals ... in their cardiology and cardiovascular surgery programs. Many institutions pioneered groundbreaking procedures and ...
(Date:12/10/2018)... ... 10, 2018 , ... Florida Hospital, soon to be AdventHealth, ... recently received the 2018 Press Ganey Guardian of Excellence Award® for achieving and ... and inpatient services is measured through random, voluntary patient surveys and the scores ...
(Date:12/8/2018)... ... December 07, 2018 , ... Caring.com, the nation’s most visited website for senior ... alert systems, to its list of top medical alert systems for 2019. The medical ... Guardian was one of fourteen companies that qualified for the list based on its ...
(Date:12/6/2018)... ... December 06, 2018 , ... We all know stress ... alternative solutions. M.D.-formulated Relaxium Calm is a dietary supplement developed to promote relaxation ... an extract of the ashwagandha root. Ashwagandha is a powerful herb that has ...
(Date:12/5/2018)... , ... December 05, 2018 , ... ... SkinPen Precision device is setting a new standard as the premier FDA-cleared microneedling ... , Each year this award is presented at the renowned Aesthetics Awards to ...
Breaking Medicine News(10 mins):
(Date:11/29/2018)... ... 29, 2018 , ... More than 205,000 individuals have signed the 4th Annual ... significantly increase funding for type 1 diabetes cure research after spending on such initiatives ... An estimated two million Americans are affected by type 1 diabetes, and about half ...
(Date:11/28/2018)... , ... November 28, 2018 , ... ... is pleased to announce a new partnership with CME Master, a division of ... Middle East, with expansion into South East Asia expected soon. This new collaboration ...
(Date:11/28/2018)... CITY (PRWEB) , ... November 28, 2018 , ... nJoy ... high levels of myopia and astigmatism in one easy procedure following FDA approval of ... the Toric ICL, is scheduled at nJoy Vision OKC on November 29th by Edward ...
Breaking Medicine Technology: