Navigation Links
Even Normal Doses Of Tylenol Could Damage Liver

People who repeatedly take acetaminophen for their aches and pains could be at an increased risk for liver damage, according to the findings of a new study// .

Researchers said that patients who repeatedly approached the maximum recommended daily dose of acetaminophen showed abnormalities in blood tests, which could indicate liver damage. They added that initially they had come across liver damage in patients who took opioid hydrocodone plus acetaminophen. Previous assumption had been that it was hydrocodone that was the culprit for liver damage, but they were surprised to find that the damage was caused by acetaminophen.

"This clearly showed, much to our jaw-dropping surprise, that it had nothing to do with the opiate," said Dr. Paul Watkins, lead author of the study. "It was a previously unrecognized but pretty remarkable effect of acetaminophen alone when taken as directed for four days."

He added that acetaminophen, which is commonly available as Tylenol, has an established safety record, so the findings were unexpected. "No one should ever take a drug they don't need," he said. "But this study is not a reason to stop taking acetaminophen if you need it."

The findings of the study are published in the July 5 issue of the Journal of the American Medical Association. 145 healthy adults were given either a placebo or one of three acetaminophen/opioid combinations, or acetaminophen alone for two weeks.

The researchers found that 31 percent to 44 percent of patients in the treatment groups had a maximum ALT measurement equal to thrice the normal value. ALT is blood aminotransferase, which indicted liver disease.

"It was so unbelievable that I am conducting an ongoing study with 50 people," Watkins said. "That's not in the JAMA paper, but we're finding that it verifies the findings. Since we have decades of experience and know the safety of acetaminophen, are the tests as good as we thought they w ere? Maybe they're not good predictors as to which drugs are going to have liver problems."
'"/>




Related medicine news :

1. Anti-Cancer Drug Restores Normal Cell Growth
2. Normal Blood Pressure Could Add Over 5 Years To Your Life
3. Language Delays May Not Be Normal In Children
4. Normal Delivery Is Better Than Caesarean Birth
5. Clinic Helps Women Lead Normal Lives
6. Premature Babies Can Lead Normal Lives
7. Health Services Returning To Normal
8. Rahul Mahajans Condition Improving; Vital Parametres Normal
9. Normalcy Returns To AIIMS; Venugopal Attends Office
10. Fiber And Fruit Key To Normal Weight
11. Craniofacial Surgery Gives Tijuana Teen Chance to be Normal Kid
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/7/2016)... ... December 07, 2016 , ... The ... its fully redesigned website, which launched October 17, 2016, features comprehensive information regarding ... and easy-to-navigate layout. Visitors and patients can discover the latest clinical dermatology treatments ...
(Date:12/7/2016)... , ... December 07, 2016 , ... Delete® - Tattoo ... Time For The Holiday Party Season. Save Up To 33% Off Botox® and Juvederm® ... is providing the Phoenix Valley with Delightful Deals on Botox® and Juvederm® ...
(Date:12/7/2016)... , ... December 07, 2016 , ... ... 20 Marketing Campaign Winner in the Folio: Marketing Awards competition. Live From won ... year’s best in pioneering, inventive, and ultimately successful projects undertaken by the media ...
(Date:12/7/2016)... ... December 07, 2016 , ... "ProBrand Flip allows FCPX editors to create ... Austin - CEO of Pixel Film Studios. , ProBrand Flip includes 30 flip book ... Editors can select from a variety of flip book animations. In Addition, users can ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... its newest portable bioelectronic medicine device WellnessPro Plus for consumers and healthcare ... enhances the WellnessPro platform by expanding the treatment modalities available in a ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016  The Corporate Whistleblower Center ... call them anytime at 866-714-6466 if they possess proof ... more drugs. Aside from the innocent patients frequently being the ... because often-times these practices target Medicare recipients or the elderly. ... ...
(Date:12/7/2016)... READING, Mass. , Dec. 7, 2016 /PRNewswire/ ... and Trace Network for connecting the Life Sciences ... the global marketplace, today announced that Tjoapack has ... European pharmaceutical manufacturing customers comply with the rapidly ... Chain Security Act (DSCSA) in 2017 and the ...
(Date:12/7/2016)... 7, 2016 According to responses from U.S. oncologists ... (38%) of patients with non-small cell lung cancer (NSCLC), treatment ... (EGFR) genetic mutation status. The findings of the survey were ... #6067 #P3.02b ) at the 2016 World Conference on ... The survey results revealed an overall high rate ...
Breaking Medicine Technology: