Navigation Links
Ethnic Variations in Hormone Levels May Cause Differences in Breast Cancer Risk

Researchers have known that a woman’s natural hormone levels can affect her risk of developing breast cancer. A new study from the University of Southern California// (USC)// has found that the natural levels of estrogens in post-menopausal women varies by ethnicity and race, and may explain the differences in the groups’ breast cancer rates. The study appears in the October issue of Cancer Epidemiology, Biomarkers & Prevention.

Using data from the Multiethnic Cohort Study, V. Wendy Setiawan, Ph.D., assistant professor of preventive medicine at the Keck School of Medicine of USC, and her colleagues determined that of the five primary ethnicities/races in the cohort, native Hawaiians have the highest risk of breast cancer—65 percent greater than whites. They also had some of the highest levels of circulating estrogens.

“We had observed that some groups, such as native Hawaiians have higher breast cancer rates compared to white women. We knew hormones are a factor, so we decided to test them,” says Setiawan. “The research seems to support that idea.”

The researchers also found that Japanese-American women have comparatively high estrogen levels and the second highest breast cancer risk of the five groups. “This is interesting because breast cancer rates have been increasing steadily in Japanese women who live in the United States, as well as in women who live in Japan,” Setiawan says. “We think it could be caused by lifestyle changes that impact age at first menstruation or other factors.”

Latinas had similar hormone profiles to whites, while women who had recently immigrated had slightly lower levels, but which were not statistically significant, the researchers found. However, Latinas’ risk of breast cancer is the lowest of the groups studied.

One of the most interesting findings was that African-American women have a slightly lower post-menopausal breast cancer risk than whites, despite having comparativel y higher post-menopausal hormone levels.

“It is known that before menopause, African-American women have a higher breast cancer risk than whites, as well as higher estrogen levels,” Setiawan says. “It would be interesting to find out why their elevated rates do not persist after menopause, despite having comparatively higher estrogen levels.”

The researchers analyzed the hormone levels in 739 postmenopausal women in the cohort who were not on hormone replacement therapy. After adjusting the hormone levels for age, body mass index, and other lifestyle factors, they then compared the levels to their ethnic/racial groups’ breast cancer incidences. The study is the largest analysis of hormone levels by ethnic group, and the first large study of native Hawaiians and Latinas.

“Clearly, more work is needed to identify factors that contribute to racial and ethnic differences in hormone levels,” Setiawan says.


Related medicine news :

1. Ethnic discrepancy in ovarian cancer
2. Death Wishes Influenced By Ethnicity and Racial Background
3. Plastic Surgery Is Primetime among Ethnic Groups
4. Specialist Services Can Help Ethnic Groups To Tackle Alcohol Misuse
5. Distinct Support Services Needed, To Resurrect Ethnic Groups from Alcohol Abuse
6. Comfort Level, Maximum in Ethnically Diverse Schools
7. Singapore Manufacturer to Bring Ethnic Foods to the World
8. Ethnic Differences in Healthcare
9. Highly Potent TB Strain Plays Favorites Targeting Specific Ethnic Groups
10. Attitude Towards Ethnic Identity Impacts Stress Levels
11. Suicide Rate Among NYs Ethnic Women is Alarming
Post Your Comments:

(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... , ... Comfort Keepers® of San Diego, CA is excited to announce they ... to drive cancer patients to and from their cancer treatments. Comfort Keepers provides ... life and ongoing independence. Getting to and from medical treatments is one of ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a ... second affiliate in Latin America . ... ... ... ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Volumes: Global Analysis (United States, China, Japan, Brazil, United ... to their offering. ... healthcare business planners, provides surgical procedure volume data in ... with an in-depth analysis of growth drivers and inhibitors, ...
Breaking Medicine Technology: