Navigation Links
Ethnic Variations in Hormone Levels May Cause Differences in Breast Cancer Risk

Researchers have known that a woman’s natural hormone levels can affect her risk of developing breast cancer. A new study from the University of Southern California// (USC)// has found that the natural levels of estrogens in post-menopausal women varies by ethnicity and race, and may explain the differences in the groups’ breast cancer rates. The study appears in the October issue of Cancer Epidemiology, Biomarkers & Prevention.

Using data from the Multiethnic Cohort Study, V. Wendy Setiawan, Ph.D., assistant professor of preventive medicine at the Keck School of Medicine of USC, and her colleagues determined that of the five primary ethnicities/races in the cohort, native Hawaiians have the highest risk of breast cancer—65 percent greater than whites. They also had some of the highest levels of circulating estrogens.

“We had observed that some groups, such as native Hawaiians have higher breast cancer rates compared to white women. We knew hormones are a factor, so we decided to test them,” says Setiawan. “The research seems to support that idea.”

The researchers also found that Japanese-American women have comparatively high estrogen levels and the second highest breast cancer risk of the five groups. “This is interesting because breast cancer rates have been increasing steadily in Japanese women who live in the United States, as well as in women who live in Japan,” Setiawan says. “We think it could be caused by lifestyle changes that impact age at first menstruation or other factors.”

Latinas had similar hormone profiles to whites, while women who had recently immigrated had slightly lower levels, but which were not statistically significant, the researchers found. However, Latinas’ risk of breast cancer is the lowest of the groups studied.

One of the most interesting findings was that African-American women have a slightly lower post-menopausal breast cancer risk than whites, despite having comparativel y higher post-menopausal hormone levels.

“It is known that before menopause, African-American women have a higher breast cancer risk than whites, as well as higher estrogen levels,” Setiawan says. “It would be interesting to find out why their elevated rates do not persist after menopause, despite having comparatively higher estrogen levels.”

The researchers analyzed the hormone levels in 739 postmenopausal women in the cohort who were not on hormone replacement therapy. After adjusting the hormone levels for age, body mass index, and other lifestyle factors, they then compared the levels to their ethnic/racial groups’ breast cancer incidences. The study is the largest analysis of hormone levels by ethnic group, and the first large study of native Hawaiians and Latinas.

“Clearly, more work is needed to identify factors that contribute to racial and ethnic differences in hormone levels,” Setiawan says.

Soure-Newswise
SRM
'"/>




Related medicine news :

1. Ethnic discrepancy in ovarian cancer
2. Death Wishes Influenced By Ethnicity and Racial Background
3. Plastic Surgery Is Primetime among Ethnic Groups
4. Specialist Services Can Help Ethnic Groups To Tackle Alcohol Misuse
5. Distinct Support Services Needed, To Resurrect Ethnic Groups from Alcohol Abuse
6. Comfort Level, Maximum in Ethnically Diverse Schools
7. Singapore Manufacturer to Bring Ethnic Foods to the World
8. Ethnic Differences in Healthcare
9. Highly Potent TB Strain Plays Favorites Targeting Specific Ethnic Groups
10. Attitude Towards Ethnic Identity Impacts Stress Levels
11. Suicide Rate Among NYs Ethnic Women is Alarming
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... ... 23, 2017 , ... In 2016 the World Health Organization declared the Zika ... million Zika-related cases in the Americas within the next year. Lyme disease is one ... year skyrocketing to an estimated 329,000. Yet, Zika, Lyme and other insect borne illnesses ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating ... communities, 16 more public health departments have been awarded national accreditation through the ... million people into the expanding network of communities across the nation whose health ...
(Date:3/23/2017)... Minneapolis, MN (PRWEB) , ... March 23, 2017 , ... ... with internet and WiFi connectivity are making a huge impact on businesses and individual ... Global Institute estimates the IoT will have a value anywhere from $4 trillion to ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... families and businesses of the Norwalk and Vermillion areas, celebrates the newest ... (N.O.R.A.) is a nonprofit, community-based substance abuse prevention and peer recovery support ...
(Date:3/23/2017)... PA (PRWEB) , ... March 23, 2017 , ... ... Patient Oriented Disease Management Accreditation from the NCQA. The accreditation covers StayWell’s asthma, ... , Accredited status is granted to organizations that have excellent programs for ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... March 23, 2017 Ascendis Pharma A/S (Nasdaq: ... technology to address significant unmet medical needs in rare ... conference call and webcast on Monday, April 3 during ... in Orlando, Florida , to discuss ... (TransCon Growth Hormone, TransCon PTH and TransCon CNP). ...
(Date:3/23/2017)... 2017 /PRNewswire/ - INVICTUS MD STRATEGIES CORP. ("Invictus MD" ... MD announces that AB Laboratories Inc. ("AB Labs") has ... facility under the Access to Cannabis for Medical Purposes ... . The facility, which was licensed ... currently operating at half capacity, with full production capacity ...
(Date:3/23/2017)... 2017 The global reprocessed ... the top five players accounting for nearly 94% ... are Stryker Sustainability Solutions, Ethicon (Johnson & Johnson), ... VANGUARD AG. Despite the high level of consolidation, ... the prevalence of fierce competition among the key ...
Breaking Medicine Technology: