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Esophageal Cancer Patients' Positive Responses to Chemotherapy Accurately Identified by PET

for other malignant diseaseslike lung, head and neck or ovarian cancerand providing information to alter treatment and patient management," he explained. "The results of our study delineate how response-guided treatment algorithms can be applied in clinical practice in the future," said Herrmann.

PET is a powerful medical imaging procedure that noninvasively demonstrates the function of organs and tissues. When PET is used to image cancer, a radiopharmaceutical (such as fluorodeoxyglucose or FDG, which which is a radioactive analog of sugar) is injected into the vein of a patient. Cancer cells metabolize sugar at higher rates than normal cells, and the radiopharmaceutical is taken up in higher concentrations to cancerous areas.

PET scans show where FDG is by tracking photons given off by the radioactive tracer. PET scanning provides information at a molecular levelnot available through other proceduresabout the body's chemistry, metabolic activity and body function.


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