Navigation Links
Epstein - Barr virus Protein Implicated in Blood Cancer

Researchers at the University Of Pennsylvania School Of Medicine had identified a link between an Epstein - Barr virus (EBV) protein and a vital cancer pathway earlier this year//. They have now proceeded further in this research and have found that the viral protein, named EBNA3C is responsible for breaking down a retinoblastoma protein.

This protein is very necessary in controlling cell proliferation. In the absence of this control, cells can begin to proliferate very rapidly and become transformed in cancer cells. The researchers have published their findings in the Proceedings of the National Academy of Sciences. Epstein-Barr virus is already implicated in diseases such as AIDS, Burkitt's lymphoma, Hodgkin's lymphoma, and nasopharyngeal carcinoma. It also causes infectious mononucleosis or kissing disease. Erle S. Robertson, PhD, an Associate Professor of Microbiology who leads the Tumor Virology Program at Penn's Abramson Cancer Center, and MD/PhD student Jason Knight are the authors of this particular paper.

Researchers feel that blocking the molecular signals caused by EBNA3C could potentially lead to development of new drugs against the virus. "Stopping this step in the life cycle of EBV could be a major potential target for the development of therapeutics for treating EBV-related B cell lymphomas," Robertson said. "This is especially important because a large percentage of patients are non-responsive to the current frontline drug for treating B cell lymphoma, a CD20 monoclonal antibody." The researchers surmise that the first use of future therapies from these studies could be in lymphoproliferative disease in transplant and immunocompromised patients."

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
'"/>




Page: 1

Related medicine news :

1. Epstein-Barr Virus May Be May Be A Cause For Multiple Sclerosis
2. Minor mutations in HIV virus
3. Infertility in relation with virus
4. Birds breed viruses
5. Hidden influenza virus protein found
6. Hepatitis E virus made impotent
7. Mutating viruses helps produce antibodies
8. Flesh-eating virus
9. Implication of virus in colon cancer
10. Colon cancer linked with common virus
11. Chances are high for Avian Influenza virus altering its form
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... ... May 03, 2016 , ... Registration is now open for the 31st annual ... at the Hatch Memorial Shell on the Esplanade. The event regularly draws thousands of participants, ... is a competitive, timed event fully sanctioned by the USA Track & Field Association. ...
(Date:5/3/2016)... ... ... Elizabeth Murray has always loved walking one to two miles a day. ... and one on her arm. But she got to the point where she could ... , The valves of the heart wouldn’t close properly resulting in mitral regurgitation, where ...
(Date:5/3/2016)... ... 03, 2016 , ... Empyrean Benefit Solutions, Inc., the Hi-Touch ... center in La Vergne, Tennessee, near Nashville. The new center will complement Empyrean’s ... client services. , “Our Nashville-area center allows us to achieve several goals,” said ...
(Date:5/3/2016)... , ... May 03, 2016 , ... Ogawa World USA ... its user friendly Samsung tablet and exclusive Smart Application. The Smart 3D combines the ... each massage with a customized user profile and specialized massage program, each user has ...
(Date:5/3/2016)... ... May 03, 2016 , ... Dr. Poneh Ghasri, cosmetic dentist in West ... new and existing patients. Cosmetic dentistry allows patients to improve the aesthetics of their ... with some minor or more serious cosmetic flaws. These specials allow patients to achieve ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... May 3, 2016  Forté Elements, LLC (Forté) is excited to announce the launch ... address the nutritional needs of recovery for a variety of clinical conditions. Founded in ... Photo - http://photos.prnewswire.com/prnh/20160502/362548 Logo -  http://photos.prnewswire.com/prnh/20160502/362547LOGO ... ... ...
(Date:5/2/2016)... , May 2, 2016 Kalorama Information ... (Electronic Medical Records) market in a recent white paper.  ... switches, Increased physician usage, a growing market are among ... noted in Kalorama,s report EMR 2016: The ... marks Kalorama,s seventh complete study of the EMR industry, ...
(Date:5/2/2016)... , May 2, 2016  While nearly three-quarters ... osteoporosis can have on their health, only about half ... according to the results of a new survey announced ... mark the start of National Osteoporosis Month, Hologic is ... which affects nearly 56 million Americans. Osteoporosis ...
Breaking Medicine Technology: