Navigation Links
EpiCept Accelerates Development of Phase I Clinical Study for Cancer

lan. We expect to be in a position to report the results of this important clinical trial later this year."

EPC2407 has shown promising vascular targeting activity with nanomolar potencies of anti-tumor activity in pre-clinical in vitro and in vivo studies. The molecule has been shown to induce tumor cell apoptosis and selectively inhibit growth of proliferating cell lines, including multi-drug resistant cell lines. Murine models of human tumor xenografts demonstrated EPC2407 inhibits growth of established tumors of a number of different cancer types more effectively than the other VDAs tested and was synergistic when used in combination with anticancer agents, such as Cisplatin. The combination of EPC2407 with other anticancer agents in a Phase 1b trial is planned to follow the current monotherapy trial. EPC2407 is one of two VDA compounds currently in clinical trials discovered through EpiCept's Anti-cancer Screening Apoptosis Program (ASAP). The second compound, Azixa(TM), is part of the EP90745 series of apoptosis inducers, which was licensed by EpiCept to Myriad Genetics, Inc. as part of an exclusive, worldwide development and commercialization agreement. Myriad recently announced that Azixa(TM) has a second mode of action due to vascular disruption activity (VDA). The compound is currently being evaluated in two Phase II human clinical trials, one in patients with primary brain cancer and the other in brain metastases due to melanoma. EpiCept's licensing agreement with Myriad for Azixa includes milestone payments, and sublicensing income as well as future royalties in the event Myriad's development of Azixa continues to progress successfully.
'"/>




Page: 1 2

Related medicine news :

1. Developmental, neurologic problems common in extremely preterm infants
2. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
3. Missing Protein In Cancer Development
4. Tomatoes Might Inhibit the Development Of Prostate Cancer
5. Pollution Found To Impair Lung Development
6. Treating Depression In Children Could Lead To Poor Bone Development
7. Developmental Origins of Polycystic Ovarian Syndrome
8. Sleep Not Critical For Early Brain Development Of Baby Dolphins
9. ‘Loud Noise’ Research may help in Development of Prosthetics for Eldery
10. Stop Watching TV: Toddler Development Affected
11. Vitamin Supplements During Pregnancy to Boost Fetal Development
Post Your Comments:
(Date:8/4/2015)... ... 04, 2015 , ... World Patent Marketing, a vertically integrated ... fitness invention that eliminates the need to have a partner or trainer when ... is worth $30 billion," says Scott Cooper, CEO and Creative Director of World ...
(Date:8/4/2015)... Birmingham, OH (PRWEB) , ... August 04, 2015 ... ... announce that it has joined the American Association of Tissue Banks (AATB) as ... AATB and its mission “to honor donors, and to save and improve lives ...
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... ... technology platform that uses Cloud innovation to consolidate oncology patient assistance programs. Through ... a single point of access. assistPoint is an enterprise level, cloud-based application and ...
(Date:8/4/2015)... ... August 04, 2015 , ... Atlantic Health System, one of the largest health ... among the top five in their list of the 20 Best Workplaces in Health ... Chilton Medical Centers, Goryeb Children’s Hospital and Atlantic Rehabilitation, is the highest-ranking company from ...
(Date:8/4/2015)... , ... August 04, 2015 , ... ... on sexual and reproductive health and rights in Indonesia for a select group ... a number of sites in Indonesia and attend the International Conference on Family ...
Breaking Medicine News(10 mins):Health News:As The Navy Changes Body-Fat Rules, the World Patent Marketing Review Team Announces the Development of the Assisted Dumbbell Bench Rack 2Health News:As The Navy Changes Body-Fat Rules, the World Patent Marketing Review Team Announces the Development of the Assisted Dumbbell Bench Rack 3Health News:As The Navy Changes Body-Fat Rules, the World Patent Marketing Review Team Announces the Development of the Assisted Dumbbell Bench Rack 4Health News:As The Navy Changes Body-Fat Rules, the World Patent Marketing Review Team Announces the Development of the Assisted Dumbbell Bench Rack 5Health News:As The Navy Changes Body-Fat Rules, the World Patent Marketing Review Team Announces the Development of the Assisted Dumbbell Bench Rack 6Health News:Exsurco Medical Joins AATB as Affiliate Member 2Health News:assistPoint.com Web Site Launched 2Health News:Atlantic Health System Named a 'Best Workplace in Health Care' by Fortune, Great Place to Work® 2Health News:Atlantic Health System Named a 'Best Workplace in Health Care' by Fortune, Great Place to Work® 3Health News:Atlantic Health System Named a 'Best Workplace in Health Care' by Fortune, Great Place to Work® 4Health News:UN Foundation Announces Press Fellowship to Indonesia with Focus on Women’s Health and Rights 2
... reward pathways as booze , TUESDAY, June 22 (HealthDay News) ... option for alcoholism, a new animal study suggests. , Alcoholism ... and eat), which leads to disrupted sleep patterns. As a ... attempt to fall asleep easier. But this often leads to ...
... 2 chances, study finds , TUESDAY, June 22 (HealthDay News) ... the waist, significantly increases your risk of type 2 diabetes, ... stable after age 50, people who gained the most weight ... of developing type 2 diabetes, according to the study in ...
... response to the H1N1 flu, most employees at U.S. businesses ... such as encouraging sick employees to stay home, according to ... Opinion Research Program at Harvard School of Public Health (HSPH). ... took other actions such as creating back-up systems for employees ...
... ... in the US to utilize Mayo Clinic Embody Health Program. , ... (PRWEB) June 22, 2010 -- St Gregory Centers, Inc. ... provide wellness programming for St Gregory clients and employees. The Mayo Clinic program will ...
... care of sick or disabled loved ones is widely recognized ... life, a new study led by University at Buffalo psychologist ... loved ones may promote the well being of helpers. "Does ... journal Psychology and Aging (2010, Vol. 25., No. ...
... risk of obesity, but a new study shows that a ... their parents helps the children reduce body fat and improve ... Society,s 92nd Annual Meeting in San Diego. Such interventions ... the study,s lead author Jardena Puder, MD, said. A senior ...
Cached Medicine News:Health News:Exercise May Combat Alcohol Cravings, Animal Study Suggests 2Health News:Gaining Weight Later in Life Ups Diabetes Risk 2Health News:Gaining Weight Later in Life Ups Diabetes Risk 3Health News:Employers took many measures to protect employees and avoid business impact of H1N1 flu outbreak 2Health News:Employers took many measures to protect employees and avoid business impact of H1N1 flu outbreak 3Health News:Employers took many measures to protect employees and avoid business impact of H1N1 flu outbreak 4Health News:St. Gregory Centers, Inc. Announces Integrating Mayo Clinic Health Wellness Program 2Health News:Study finds that caring for an elderly, sick spouse sometimes has positive elements 2Health News:Lifestyle intervention reduces preschoolers' body fat, improves fitness 2
(Date:8/4/2015)... HeartWare International, Inc . (NASDAQ: ... circulatory support technologies that are revolutionizing the treatment of ... Chief Executive Officer, Doug Godshall , is scheduled ... Conference at 8:30 a.m. EDT on Thursday, August 13, ... at the InterContinental Boston. A live webcast ...
(Date:8/4/2015)... , Aug. 04, 2015 ... has announced the addition of the "MRI ... Comfort and Operational Efficiency, with Growth Driven by ... "MRI Systems Market to 2020 - Focus ... Driven by Developing Economies" discusses the market, competitive ...
(Date:8/4/2015)...  Dr. Keesha Ewers of The ... of flibanserin, or what is being touted as ... decreased female sexual desire back several decades. Diminished ... addressing libido as a singular symptom with a ... Photo - http://photos.prnewswire.com/prnh/20150804/254705 ...
Breaking Medicine Technology:HeartWare Presentation At The Canaccord Genuity 35th Annual Growth Conference To Be Webcast 2Global MRI Systems Market Outlook to 2020 - Focus on Patient Comfort and Operational Efficiency, with Growth Driven by Developing Economies 2Potential FDA Approval of "Pink Viagra" Sends Wrong Message 2Potential FDA Approval of "Pink Viagra" Sends Wrong Message 3Potential FDA Approval of "Pink Viagra" Sends Wrong Message 4Potential FDA Approval of "Pink Viagra" Sends Wrong Message 5
... Open-Label Study Presented at Federation of,Clinical Immunology ... June 11, 2007 /PRNewswire-FirstCall/ --,Orchestra Therapeutics, Inc. ... from its completed Phase II open-label study ... peptide,vaccine for the treatment of relapsing-remitting multiple ...
... -- NovaCardia, Inc.,today presented preliminary results from a ... receptor antagonist in development for the,treatment of patients ... strong trend toward efficacy for the 30 milligram,dose. ... of,improvement in dyspnea, or shortness of breath, which ...
Cached Medicine Technology:Orchestra Therapeutics Announces New Phase II Clinical Data on,NeuroVax Demonstrating Marked Expansion of Regulatory T Cell,Populations in Patients With Multiple Sclerosis 2Orchestra Therapeutics Announces New Phase II Clinical Data on,NeuroVax Demonstrating Marked Expansion of Regulatory T Cell,Populations in Patients With Multiple Sclerosis 3Orchestra Therapeutics Announces New Phase II Clinical Data on,NeuroVax Demonstrating Marked Expansion of Regulatory T Cell,Populations in Patients With Multiple Sclerosis 4Orchestra Therapeutics Announces New Phase II Clinical Data on,NeuroVax Demonstrating Marked Expansion of Regulatory T Cell,Populations in Patients With Multiple Sclerosis 5Pilot Phase 3 Results of NovaCardia's KW-3902 for Acute Congestive,Heart Failure Presented at Late-Breaking Session of Heart Failure,Congress 2007 2Pilot Phase 3 Results of NovaCardia's KW-3902 for Acute Congestive,Heart Failure Presented at Late-Breaking Session of Heart Failure,Congress 2007 3Pilot Phase 3 Results of NovaCardia's KW-3902 for Acute Congestive,Heart Failure Presented at Late-Breaking Session of Heart Failure,Congress 2007 4
... 12 mm linear cutting stapler for resection, ... ,The stapler places two triple, staggered rows ... divides the tissue in between. The instrument ... single surgical procedure: it can be reloaded ...
Single Use Loading Units with Titanium Staples for use with Powered MULTIFIRE ENDO GIA™ 60 (15 mm Single Use Stapler with Titanium Staples)....
Single Use Loading Units (SULU's) with Titanium Staples for use with MULTIFIRE ENDO GIA™ 30 12 mm (Single Use Staplers with Titanium Staples)....
ENDO GIA ROTICULATOR™ Single Use Loading Units with Titanium Staples for use with the ENDO GIA™ Universal and GIA™ Universal Instrument (030403) Single Use Instrument (030449)....
Medicine Products: