Navigation Links
Enzyme supply may improve Alzheimer’s condition.

A pioneering drug treatment has revealed that memory function can be restored in mice afflicted with Alzheimer’s disease.//

Dr. Michael Shelanski, director of the Alzheimer's Research Center at Columbia University and his colleagues carried out this study. They treated mice whose brains were already clogged with the amyloid plaques. These plaques are responsible for the irreversible brain damage characteristic of the disease. The same drug may, sometime in future, treat humans with late-stage Alzheimer’s.

Destruction of the plaques and prevention of new ones from forming, are the areas where already existing treatments and vaccines work. This recent treatment aims at a different part of the brain and is effective irrespective of the presence or absence of the plaques. The idea is to help brain cells remove unwanted or over-abundant proteins.

There's no way to know if the approach will work in humans, but researchers are hopeful. In essence, "we were able to restart -- or make more efficient -- the garbage disposal function of the cell," said Dr. Shelanski.

The amyloid beta plaque protein, which is abundant in people with Alzheimer’s, when comes in contact with healthy brain cells results in a decrease of the enzyme responsible for protein disposal called ubiquitin C-terminal hydrolase L1 (Uch-L1).

This results in disruption of protein disposal and hence, they got accumulated in the brain cells of the Alzheimer’s patient.

The team provided extra supplies of the missing enzyme to both brain tissues grown in the lab and to mice with the equivalent of Alzheimer’s disease and studied its effect.

Exposure of healthy brain cells to amyloid beta protein results in disruption of neurotransmission. This condition was reversed by the extra supply of the enzyme Uch-L1. This was tested on mice with the rodent equivalent of Alzheimer’s disease. When the enzyme was supplied to the mice through an injecti
'"/>




Page: 1 2

Related medicine news :

1. Enzyme may be target for obesity drugs
2. Researchers trick Alzheimers Enzyme
3. Enzyme stimulates growth of adult stem cells
4. Enzyme may aid hold back disease
5. Enzyme help destroy cancer cell
6. Enzyme Associated with Memory
7. Enzyme Associated With Memory
8. Brain Enzyme Found To Regulate Weight
9. New Enzyme Identified For Arthritis
10. Enzyme for treatment of arthritis
11. An Enzyme That Turns a One –time Experience into a long-time Memor
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Enzyme supply may improve Alzheimer condition

(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who ... are thrilled to have it lead the wedding dress industry ... of prom dresses for the global market. , “The CEO ... and he focuses on continuing the goal of operational excellence ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Blue Cross and ... Minnesotans who exemplify what it means to “Live Fearless.” ... for people to share their stories about how they or ... simply inspired others by living in the moment. By telling ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Juvent Sports ... at the 2015 PGA Merchandise Show to bestow a ... incredible female amateur golfer, Arlene McKitrick. The award commemorated ... amateur golf tournament win. She won her first amateur ...
(Date:1/22/2015)... 2015 Autocarinsurancebest.com has released a new blog ... auto insurance policy . , Auto insurance quotes help ... is no longer necessary to call an agent or visit ... online on a single website: http://autocarinsurancebest.com/ . , Every ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved ... upcoming 32nd Annual Miami Breast Cancer Conference ... LLC (PER®) , shares that “a fast-growing, virulent” cancer ... she had not followed up her clean mammogram with ...
Breaking Medicine News(10 mins):Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... 2009)Fox Chase Cancer Center researchers report that a combination ... inhibitor of the HER2 receptor (ErbB2) appears active in ... on previous trastuzumab based therapies. More than one-quarter ... their tumors shrink on the combination therapy. , ...
... Laboratories, Inc. (Nasdaq: IDXX ), announced today that ... Annual Growth Stock Conference. Jonathan Ayers, Chairman and CEO, is ... June 9, 2009 at 10:50 a.m. (Central Time), at the ... audio webcast of the presentation through a link on the ...
... Darwin National,Assurance Company, a member company of ... AWH ), today announced that Becky Cox has ... role, Ms. Cox will,be responsible for the continued ... alongside Fred Bautista, Vice,President, Business Development, Healthcare. , ...
... Monday, June 1, 20091:30 to 2:30 p.m. Rooftop garden offers patients quiet haven, conservatory features ... Aurora St. Luke,s Medical Center is dedicating the Vince, ... Funds Healing Garden and the Agnes and, ... Monday, June 1, 1:30 to 2:30 p.m., WHERE: ...
... Francisco-to-Los Angeles ride May 31SAN FRANCISCO and LOS ANGELES, ... states and 14 nations will stream out of San ... as participants in the colorful and emotional AIDS/LifeCycle, the ... to raise more than $10 million to support vital ...
... May 28 (HealthDay News) --Should it worry you that there ... , Not especially, when you consider that there are 44 ... , This information comes to you from scientists at the ... same techniques that enabled them to map the human genetic ...
Cached Medicine News:Health News:Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer 2Health News:Darwin Appoints Becky Cox Vice President, Business Development, Healthcare 2Health News:Darwin Appoints Becky Cox Vice President, Business Development, Healthcare 3Health News:AIDS/LifeCycle 8 to Raise $10+ Million to Fight AIDS 2Health News:AIDS/LifeCycle 8 to Raise $10+ Million to Fight AIDS 3Health News:Study Finds Multitude of Bacteria on Human Skin 2Health News:Study Finds Multitude of Bacteria on Human Skin 3
(Date:1/23/2015)... 2015  Today the U.S. Food and Drug Administration (FDA) ... of serogroup B meningococcal disease in individuals ... which received FDA approval in October, represent a significant ... "I have heard over and over from ...
(Date:1/23/2015)... , Jan. 23, 2015 A lot of discussion ... methods for treating  certain illnesses, injuries, or conditions. As medical ... previous treatment methods with ones that they consider to be ... there is not one textbook method of treatment that stands ...
(Date:1/23/2015)... DES MOINES, Iowa , Jan. 23, 2015  The Partnership to ... Iowa health care leaders and a new study ... prescription medications. The PFCD is a nationwide coalition working to educate ... The research released at the Capitol was focused on how the ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3
... ALISO VIEJO, Calif., May 1, 2012   Avanir Pharmaceuticals, Inc. ... for the quarter ended March 31, 2012 before market open ... conference call and an audio webcast at 9:00 am Eastern ... Conference Call Information: Domestic callers: 1 (866) 543-6411 ...
... today the addition of 8000 square feet to ... next to the company,s flagship showroom, will house ... launched lab equipment maintenance and repair department. ... In celebration of the expansion, and to show ...
Cached Medicine Technology:BioSurplus Expands, Debuts New 8000 Square Foot Warehouse and Service Facility 2
Rotating 360 degrees, 3 mm x 7 mm bite....
45 degree, forward 3 mm, 4 mm x 5 mm cup, length of shaft 140 mm, overall length 8.3 inches....
20 mm. Plastic, methylmethacrylate. Supplied sterile....
Small right. Teflon orbital plates....
Medicine Products: