Navigation Links
Enriching Environment Stimulates Neurons: Hope For Fragile X Syndrome

A new finding by a team of researchers, led by Huibert Mansvelder reveals that a stimulating environment can restore the malfunctioning neuronal machinery of Fragile X syndrome . The findings have been published in the May 24, 2007 issue of the journal Neuron, published by Cell Press.

A type of inherited mental retardation; Fragile X syndrome affects 1 in 3600 males and 1 in 4000 to 6000 females. The researchers carried out studies on mice that were genetically altered to match the defects in humans with this mental disorder. The scientists performed a detailed analysis of the electrophysiological properties of neurons in the prefrontal cortex, a region responsible for higher cognitive functions, including learning and memory, that are affected in humans with the disorder.

The scientists analysis revealed that the neurons in the mice showed reduction of a particular form of a process called "long-term potentiation" that is central to the formation of new circuit pathways in learning and memory. The researchers experiments showed that this reduction was due to abnormalities in the pore-like channels that regulate the flow of calcium into neurons.

Importantly, they found that increased stimulation of neurons in the mice, which enhanced calcium signaling, could restore normal long-term potentiation and neuronal plasticity.

There have been reports that Fragile X patients can still learn and memorize information but need more repetition and stimulation. Also, studies by other researchers had shown that exposing Fragile X knockout mice to a stimulating environment ameliorated behavioral and neuronal abnormalities.

So, Mansvelder and colleagues tested whether exposure of the knockout mice to an enriched environment caused higher stimulation that would restore normal neuronal plasticity. They gave such mice a variety of cage toys, and also gave them time in play cages that contained running wheels, tunnel
'"/>




Page: 1 2

Related medicine news :

1. GlaxoSmithKline To Cultivate Non-Smoking Environment
2. Alcoholism Influenced By Both Genetics & Family Environment
3. Environment and Diet Found To Precipitate Asthma
4. Environmental Factors Found To Have An Impact On The Sex of A Child
5. Environmental Factors Found To Have An Impact On The Sex of A Child
6. Environmental estrogens can cause breast cancer
7. Athletes Are More Prone To Environmental Pollutants Due To Choice Of Diet
8. Industrial and Environmental pollutants increase diabetes risk
9. Environment a major factor in occurrence of Type 2 Diabetes
10. Environmental Abuse Causes Health Hazards
11. Urban Built Environment May Play a Vital Role in Influencing the Body Size
Post Your Comments:
(Date:8/27/2015)... ... August 27, 2015 , ... In ... legal marijuana industry with the launch of its Doobster platform, a HIPAA-compliant mobile ... order products from their smart phones and tablets. Well, Doobster, “The App ...
(Date:8/27/2015)... ... August 27, 2015 , ... The Naderi Center is proud to announce that ... noninvasive procedure to improve submental fat. The first and only Food and Drug ... Dr. Kulak is the only Board Certified surgeon in the D.C., Maryland, Virginia ...
(Date:8/27/2015)... ... August 27, 2015 , ... Zensah®, the ... professional Tennis player for Israel in the Women’s Tennis Association (WTA). Glushko competes ... training and recovery. , With a focus on technology and comfort, Zensah® has ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... company and leading biopharmaceutical contract development manufacturing company (CDMO), announced today that it ... (“Hepalink”) for $205.68M in cash. , The addition of Cytovance Biologics ...
(Date:8/27/2015)... Coppell, TX (PRWEB) , ... August 27, 2015 , ... ... a cutting edge procedure to relieve vaginal discomfort due to pre- and post-menopause, chemotherapy, ... treatment using a CO2 laser, which delivers controlled energy to the vaginal tissue, revitalizing ...
Breaking Medicine News(10 mins):Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 3Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 4Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 5Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 2Health News:Noninvasive Double Chin Elimination Now Available in Herndon and Chevy Chase 3Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 2Health News:Zensah® Compression Announces Partnership with WTA Tennis Professional Athlete, Julia Glushko 3Health News:Great Point Partners, LLC Announces that Hepalink USA Inc. Agrees to Acquire Cytovance Biologics, Inc. 2Health News:Great Point Partners, LLC Announces that Hepalink USA Inc. Agrees to Acquire Cytovance Biologics, Inc. 3Health News:Great Point Partners, LLC Announces that Hepalink USA Inc. Agrees to Acquire Cytovance Biologics, Inc. 4Health News:LifeStream Health Centre & MedSpa Announces New Treatment for Vaginal Discomfort 2Health News:LifeStream Health Centre & MedSpa Announces New Treatment for Vaginal Discomfort 3
... beef bought from stores caused E.Coli outbreak. Seven persons took ... they recovered. Severe stomach cramps and diarrhea are the known ... believed to be responsible for supplying tainted stuff, withdrew nearly ... ,The US Department of Agriculture confirmed that PM ...
... widespread disgust and outrage expressed over the housing together of ... Wheeler, 43, and his boyfriend Victor Leslie Urquhart, 46, ... ,The two men were convicted last ... for 20 days, before he was rescued. The pair had ...
... have had a stroke are almost twice as likely as the ... That risk can be even higher depending on the race and ... study looked at the risk of stroke for 807 siblings of ... the strokes were either an ischemic stroke in which a vessel ...
... due to sunstroke in the past two months across Orissa, ... been reported from the southern district of Ganjam, one death ... Kendrapada, Nuapada and Sundergarh, D.N. Sahu, an official of the ... complaints of about 53 deaths due to sunstroke from various ...
... have been victims of sex abuse, bullying or other threats, ... conducted by National Society for the Prevention of Cruelty to ... protection and the prevention of cruelty to children, revealed that ... ,The survey is a part of NSPCCs Dont ...
... doctors against exposing patients to CT scans unnecessarily because the ... ,They suggest that the amount of radiation ... some cases be equivalent to that received by some survivors ... ,According to some estimates, the radiation exposure a patient receives ...
Cached Medicine News:Health News:Beef Firm in US Withdraws Its Products from Markets After E. Coli Outbreak. 2Health News:Outrage Against Gay PartnersInCrime Kept Together 2Health News:Stroke Risk Nearly Doubles for Siblings of People Who Have Had a Stroke 2
(Date:8/27/2015)... August 27, 2015 According to a new ... Toilet, Seating, Universal, Standing, Bariatric ), Material (Nylon, Padded, Canvas), Usage ... 2020", published by MarketsandMarkets, the Medical Lifting Sling Market is poised ... in 2015, at a CAGR of 11.4 % from 2015 to ... ma rket data T ables and 65 ...
(Date:8/27/2015)... Ala. , Aug. 27, 2015 /PRNewswire/ ... Outpatient Pharmacy Provider (IOPP™) is expanding its ... of a medication-focused transition of care program ... named "RxCare Management," provides hospitals with technology ... hospital performance measures that have been mandated ...
(Date:8/27/2015)... Aug. 27, 2015 NorthStar Anesthesia , one ... it has been selected by Mercy, based in ... four of their hospitals:  Mercy St. Vincent  Medical Center and ... , Mercy St. Charles  Hospital in Oregon ... Tiffin . "As we looked to ...
Breaking Medicine Technology:Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4Rx Care Management by Proxsys Rx - Transition of Care Technology Helps Prevent Hospital Medication Errors 2Four Mercy Hospitals in Northwest Ohio Select NorthStar Anesthesia 2
... 2011 The ophthalmic therapeutics company Xcovery Vision announced ... and Dr. Ken Mandell, President and COO, will be ... Ophthalmology (ARVO) Annual Meeting in Fort Lauderdale Florida, May ... Serial Entrepreneur recounts his repeated success as founder ...
... Pharmacal Company, LLC has become aware of a broad ... Pads, manufactured by H&P Industries Inc. and marketed under ... Prep Pads were included in the Atwater Carey First ... interest of consumer safety, Wisconsin Pharmacal wants to ensure ...
Cached Medicine Technology:Xcovery Vision Founders to Speak at ARVO 2011 2Important Information for Atwater Carey First Aid Kit Consumers Regarding Triad Group's Povidone Iodine Prep Pads 2
... instrument is a self-contained, compact, easy-to-use, bedside ... reagents, the Ichor system provides a hematology ... count plus platelet aggregation within five minutes. ... blood sample is added to both an ...
... Immedia PT System is an in vitro ... (PT) results, expressed in seconds and INR ... blood. It is intended for use by ... care to monitor patients who are on ...
... family, which includes the world's smallest ... most advanced pacemaker technology available, including ... first and only U.S. commercially approved ... (AF). The AF Suppression algorithm in ...
... IntelliVue Information Center combines the ... station with sophisticated clinical analysis tools. ... with Philips innovative portal technology so ... side by side with digital radiology ...
Medicine Products: