Navigation Links
Enriching Environment Stimulates Neurons: Hope For Fragile X Syndrome

A new finding by a team of researchers, led by Huibert Mansvelder reveals that a stimulating environment can restore the malfunctioning neuronal machinery of Fragile X syndrome . The findings have been published in the May 24, 2007 issue of the journal Neuron, published by Cell Press.

A type of inherited mental retardation; Fragile X syndrome affects 1 in 3600 males and 1 in 4000 to 6000 females. The researchers carried out studies on mice that were genetically altered to match the defects in humans with this mental disorder. The scientists performed a detailed analysis of the electrophysiological properties of neurons in the prefrontal cortex, a region responsible for higher cognitive functions, including learning and memory, that are affected in humans with the disorder.

The scientists analysis revealed that the neurons in the mice showed reduction of a particular form of a process called "long-term potentiation" that is central to the formation of new circuit pathways in learning and memory. The researchers experiments showed that this reduction was due to abnormalities in the pore-like channels that regulate the flow of calcium into neurons.

Importantly, they found that increased stimulation of neurons in the mice, which enhanced calcium signaling, could restore normal long-term potentiation and neuronal plasticity.

There have been reports that Fragile X patients can still learn and memorize information but need more repetition and stimulation. Also, studies by other researchers had shown that exposing Fragile X knockout mice to a stimulating environment ameliorated behavioral and neuronal abnormalities.

So, Mansvelder and colleagues tested whether exposure of the knockout mice to an enriched environment caused higher stimulation that would restore normal neuronal plasticity. They gave such mice a variety of cage toys, and also gave them time in play cages that contained running wheels, tunnel
'"/>




Page: 1 2

Related medicine news :

1. GlaxoSmithKline To Cultivate Non-Smoking Environment
2. Alcoholism Influenced By Both Genetics & Family Environment
3. Environment and Diet Found To Precipitate Asthma
4. Environmental Factors Found To Have An Impact On The Sex of A Child
5. Environmental Factors Found To Have An Impact On The Sex of A Child
6. Environmental estrogens can cause breast cancer
7. Athletes Are More Prone To Environmental Pollutants Due To Choice Of Diet
8. Industrial and Environmental pollutants increase diabetes risk
9. Environment a major factor in occurrence of Type 2 Diabetes
10. Environmental Abuse Causes Health Hazards
11. Urban Built Environment May Play a Vital Role in Influencing the Body Size
Post Your Comments:
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... the US consumer product safety commission. This number is far ... are mainly related to the children as they are the ... in an increase in the emergency room visit. ... the sidewalk, through crowded malls and playgrounds. , ...
... cause of concern as most of them are related to ... health problems due to which people abstained from work. ... and Development (CIPD) on about 30,000 workers revealed that mental ... to muscle related problems like bad back. ,The ...
... of Alzheimer's disease nationwide, both the New York State ... a resolution aimed at raising awareness of the importance ... brain disorder. ,The resolution declared November 2007 ... as Memory Screening Day in New York State. ...
... Advanced Bio-Surfaces, Inc., (ABS) an orthopedic implant developer and ... been completed in the United States using the OrthoGlide ... implant designed to relieve chronic, disabling pain, due to ... ,"There has been a significant increase in ...
... products and medicines has the potential to reach Rs.120 billion ... of exclusive export promotion zones (EPZ) across India, says ... accelerated with the setting up of EPZs in about 12 ... over 25 percent in countries like the US, Britain, Spain, ...
... also known as marijuana or ganja, can help in ... occur when body tissues are attacked by its own ... at the University of Bonn, used tetrahydrocannabinol (THC), the ... and found that it reduced skin allergies. ...
Cached Medicine News:Health News:1,600 Roller Shoe Injuries Reported 2Health News:Mental Illness Foremost Reason for Absenteeism 2Health News:New York Legislature Highlights for Awareness of Alzheimer's Disease 2Health News:New York Legislature Highlights for Awareness of Alzheimer's Disease 3Health News:Export of Herbal Products to Reach Rs.120 Billion by 2012: Study 2
(Date:12/24/2014)...  The American Diabetes Association is recommending a ... with diabetes and that all people with diabetes ... in keeping with recent changes to guidelines for ... of Cardiology (ACC) and American Heart Association (AHA). ... changes to the Association,s annual revised Standards of ...
(Date:12/22/2014)... , Dec. 22, 2014  CytoSorbents Corporation ... its CytoSorb® blood purification technology to help fight ... in 28 countries worldwide, today announced the appointment ... MD, FACS, as its Senior Vice President of ... Dr. Di Russo is an ...
(Date:12/22/2014)... 2014 Research and Markets ( ... "Investment Analysis of the US Medical Device ... http://photos.prnewswire.com/prnh/20130307/600769 ... device sector identifies the key trends and rationale ... and mergers and acquisitions. The study ...
Breaking Medicine Technology:New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5Investment Analysis of the US Medical Device Sector 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: