Navigation Links
Enriching Environment Stimulates Neurons: Hope For Fragile X Syndrome

A new finding by a team of researchers, led by Huibert Mansvelder reveals that a stimulating environment can restore the malfunctioning neuronal machinery of Fragile X syndrome . The findings have been published in the May 24, 2007 issue of the journal Neuron, published by Cell Press.

A type of inherited mental retardation; Fragile X syndrome affects 1 in 3600 males and 1 in 4000 to 6000 females. The researchers carried out studies on mice that were genetically altered to match the defects in humans with this mental disorder. The scientists performed a detailed analysis of the electrophysiological properties of neurons in the prefrontal cortex, a region responsible for higher cognitive functions, including learning and memory, that are affected in humans with the disorder.

The scientists analysis revealed that the neurons in the mice showed reduction of a particular form of a process called "long-term potentiation" that is central to the formation of new circuit pathways in learning and memory. The researchers experiments showed that this reduction was due to abnormalities in the pore-like channels that regulate the flow of calcium into neurons.

Importantly, they found that increased stimulation of neurons in the mice, which enhanced calcium signaling, could restore normal long-term potentiation and neuronal plasticity.

There have been reports that Fragile X patients can still learn and memorize information but need more repetition and stimulation. Also, studies by other researchers had shown that exposing Fragile X knockout mice to a stimulating environment ameliorated behavioral and neuronal abnormalities.

So, Mansvelder and colleagues tested whether exposure of the knockout mice to an enriched environment caused higher stimulation that would restore normal neuronal plasticity. They gave such mice a variety of cage toys, and also gave them time in play cages that contained running wheels, tunnel
'"/>




Page: 1 2

Related medicine news :

1. GlaxoSmithKline To Cultivate Non-Smoking Environment
2. Alcoholism Influenced By Both Genetics & Family Environment
3. Environment and Diet Found To Precipitate Asthma
4. Environmental Factors Found To Have An Impact On The Sex of A Child
5. Environmental Factors Found To Have An Impact On The Sex of A Child
6. Environmental estrogens can cause breast cancer
7. Athletes Are More Prone To Environmental Pollutants Due To Choice Of Diet
8. Industrial and Environmental pollutants increase diabetes risk
9. Environment a major factor in occurrence of Type 2 Diabetes
10. Environmental Abuse Causes Health Hazards
11. Urban Built Environment May Play a Vital Role in Influencing the Body Size
Post Your Comments:
(Date:7/22/2014)... 22, 2014 Cumberland Pediatric Dentistry ... dental experience that values anxiety-free dental care for children, ... for a child's dental care. , The orthodontic ... care to infants, adolescents, adults and those with special ... physical disability, or require unique care, such as cleft ...
(Date:7/22/2014)... 2014 NOVAtime Technology, Inc. ( ... and Attendance / Workforce Management solutions, announced today ... customer since 2007, has upgraded to NOVAtime ... state-of-the-art, web-based time and attendance / workforce management ... is a human services agency that provides support ...
(Date:7/22/2014)... Colorado (PRWEB) July 22, 2014 CareTouch ... called CareTouch in the Community . CareTouch employees ... year, and provide hands-on support in line with their ... improve their health. The program’s first cause is Hike ... Hospice. , On Sunday, September 14, the CareTouch ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 The ... Group are now offering robotic assisted laser therapy ... best solutions for men and women suffering from ... procedure they now offer Follicular Unit Extraction (FUE) ... medical robot. With this new technology, their doctors ...
(Date:7/22/2014)... 22, 2014 The physical demands of ... plyometrics, powerlifting, gymnastics, kettleball lifting, calisthenics, and strongman exercises ... Jason Sobzcak, co-owner of CrossFit East Cobb, ... because extreme workouts like these require high quality supplementation. ... I need to take in about 160 grams of ...
Breaking Medicine News(10 mins):Health News:Cumberland Pediatric Dentistry and Orthodontics of Clarksville Welcomes Dr. Peter Wojtkiewicz, Pediatric Orthodontist 2Health News:Cumberland Pediatric Dentistry and Orthodontics of Clarksville Welcomes Dr. Peter Wojtkiewicz, Pediatric Orthodontist 3Health News:Lutheran Services in Iowa Upgrades to NOVAtime 4000 Time and Attendance / Workforce Management Solution; Benefits from Labor Costing Functionality 2Health News:Lutheran Services in Iowa Upgrades to NOVAtime 4000 Time and Attendance / Workforce Management Solution; Benefits from Labor Costing Functionality 3Health News:CareTouch is a Peak Sponsor for the 9th Annual Hike for Hospice in Morrison, Colorado 2Health News:WeGrowHair.com/PAI Medical Group Introduces Robotic Assisted Laser Therapy to Treat Hair Loss 2Health News:CrossFit East Cobb Fuels Their Intense Workouts with All-Natural EnergyFirst Supplements 2Health News:CrossFit East Cobb Fuels Their Intense Workouts with All-Natural EnergyFirst Supplements 3
... to be a major complication of diabetes, despite the ... amputations are currently performed among the diabetic population. ... in the retinas of about 900 diabetic patients who ... All were followed for 20 years to assess how ...
... new study shows hydrotherapy, or water exercise, may improve strength ... Australia studied more than 100 patients with osteoarthritis who were ... The first group exercised three times a week in a ... third did not exercise at all. Both the water and ...
... Chronic lung disease is a primary long-term complication among ... are at greater risk for pulmonary hypertension and impaired ... risk of developing neurological problems. ,A new ... benefit from treatment with inhaled nitric oxide. ,Researchers ...
... pain, pelvic pressure, frequent urination or abnormal periods, uterine ... found in the uterus and can// range in size ... or larger. Now, there’s an improvement to uterine fibroid ... choice for many women. ,Sabrina Figueroa considers herself ...
... back pain is when symptoms have lasted for less ... program that includes group classes, exercise sheet// handouts, and ... their back pain. ,Researchers from Indiana University ... low back pain. The program focuses on boosting confidence ...
... years, Keith Black, M.D., from Cedars-Sinai Medical Center in Los ... cancer. While his research moves forward, he’s helping patients ... tumor vaccine. Dr. Black says brain tumors ... the immune system could use to recognize the tumor. By ...
Cached Medicine News:Health News:Uterine Fibroid Embolization Gaining Popularity 2Health News:New vaccine for brain cancer 2
(Date:7/21/2014)... PLEASANTON, Calif. , July 21, 2014 ... leader in device-based mechanical circulatory support therapies to save, ... will report its operating results for the second quarter ... The company will hold a conference call to ... all interested parties, at 1:30 p.m., Pacific Daylight Time ...
(Date:7/21/2014)... PORTLAND, Oregon , July 21, 2014 /PRNewswire/ ... by Allied Market Research titled, "Global biosimilars/follow-on-biologics market ... Trends, Company Profiles, Demand, Insights, Analysis, Research, Report, ... that the global biosimilars market would reach $35 ... in 2013. Deeper penetration with clearer regulatory pathways ...
(Date:7/21/2014)... By order of the U.S. Bankruptcy Court, Tiger Group,s Remarketing ... optical equipment, designer eyeglass frames, and other assets of ... LLC. Online bidding opens July 21 at ... style, on July 28 beginning at 10:30 a.m. (ET). Previews ... 25 th and 26 th at 12 locations ...
Breaking Medicine Technology:Thoratec Schedules Second Quarter Conference Call, Webcast 2Biosimilars/Follow-on-Biologics Market is Expected to Reach $35 Billion, Globally, by 2020 2Biosimilars/Follow-on-Biologics Market is Expected to Reach $35 Billion, Globally, by 2020 3Biosimilars/Follow-on-Biologics Market is Expected to Reach $35 Billion, Globally, by 2020 4Auction Set For Assets Of National Optical Services Company 2
... Manufacturing - Has Potential to Address Gaps in Global ... World Health Organization Meeting on Evaluation of Pandemic Influenza ... NVAX ) announced favorable results from the second ... its pandemic influenza virus-like particle (VLP) vaccine candidate. ...
... Scientists announced today the,publication of a landmark peer-reviewed ... Stem Cell Journal which outlines the long term ... neural stem cells for the,treatment of Parkinson,s disease. ... FACS, "We have documented the first successful adult,neural ...
Cached Medicine Technology:Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference 2Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference 3Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference 4Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference 5Groundbreaking Paper Publishes Long Term Results of a Successful Phase I Clinical Trial Using Autologous Neural Stem Cells to Treat Parkinson's Disease 2Groundbreaking Paper Publishes Long Term Results of a Successful Phase I Clinical Trial Using Autologous Neural Stem Cells to Treat Parkinson's Disease 3
Compact, bench-top analyser with minimal water volume requirements and easy waste management....
Compact benchtop clinical chemistry system...
... 350 Chemistry System offers easy operation, maintenance, and ... STAT, or back-up to the powerful VITROS 5,1 ... the job done right the first time. Its ... are efficient, dependable, and easy-to-use. The VITROS 350 ...
Meet Galileo, the best reason to move to automation; the best way to upgrade your capabilities....
Medicine Products: