( or during surgery; (2) empiric - prescr...)Efforts to Check Uncontrolled use of Antibiotics and Antibiotic Resistance,Health

or during surgery; (2) empiric - prescribed before the physician knows the specific nature of the bacteria; and (3) targeted - prescribed after bacterial culture results identify the bacteria actually causing the infection.

The study found that if a hospital had implemented measures to control the duration of administration of an empiric antibiotic, the institution had lower antibiotic resistance rates.

Having a restricted hospital formulary that limited the antibiotics available in the hospital was associated with a higher prevalence of antibiotic resistance, while simply limiting broad spectrum drugs helped prevent resistance.

"We think this may be because wrong decisions are made about which antibiotics are made available. Other studies have shown evidence that restricting formularies to previously effective antibiotics can actually help control antibiotic resistance," said Dr. Doebbeling.

"Antibiotic resistance is a growing problem for healthcare. Showing that recommended measures seem to prevent it in this nationally representative sample of hospitals is really encouraging," he said.

Source-Eurekalert
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