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Efforts to Check Uncontrolled use of Antibiotics and Antibiotic Resistance

Researchers from the Indiana University School of Medicine, the Regenstrief Institute, Inc. and the Richard Roudebush Veterans //Administration Medical Center have noted in a research regarding guidelines that control antibiotics and antibiotic resistance in hospitals, that the hospitals which adhere to national guide lines which have been laid down to control the use of antibiotics report considerably lower rates of antibiotic resistance as well.

The researchers in their extensive work studied four different types of antibiotic resistance at 450 major hospitals and explored the methods employed by these hospitals to control the use of antibiotics and studied closely if the methods employed helped to bring down the rates of antibiotic resistance.

"We saw in this study, as in other work we have done, that antibiotic resistance is increasing rapidly. This increase is seen in all types of hospitals across the country - large and small, teaching and non-teaching, VA and non-VA," said Bradley N. Doebbeling, M.D., M.Sc., who led the study. He directs the IU Center for Health Services and Outcomes Research at the Regenstrief Institute and the IU School of Medicine. He also directs the VA Center for Implementing Evidence-Based Practice.

The study looked at measures to prevent development of antibiotic resistance as well as ways to stop its spread. The researchers reported that if hospitals implemented specific measures to control the use of antibiotics they were more likely to have succeeded in controlling antibiotic resistance.

Surprisingly, use of information technology didn't seem to have an impact. "We think that's because so few hospitals have the necessary technology available to support decisions related to prescribing antibiotics such as start and stop rules and how to use the best drug," said Dr. Doebbeling.

Prescription of antibiotics fall into three categories (1) preventive, often administered before
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