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Effectiveness of Hormone Therapy During Menopause

whether a natural, human form of estrogen, administered via an arm patch, has more benefit and less negative effect than the commonly used oral form of estrogen that is synthesized in the laboratory from animal sources. Researchers also hope to find that with younger women, the natural form of estrogen therapy can be administered for a much shorter period, with positive gains in cognition later in life.

The study also hopes to determine the best way to counteract the adverse effects of estrogen on the lining of the uterus, which hormone therapy regimen best mimics the menstrual cycle, and the relationship, if any, between estrogen-induced changes in markers of atherosclerosis, heart disease, inflammation, and blood hypercoagulability.


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